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Director’s Blog

The Ignorance Project

At the recent World Economic Forum, brain research was a hot topic; Dr. Insel reports on statistics presented at the conference that inspire optimism that progress can be made on difficult problems, including mental disorders.

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Funding Science

Relative to other countries, U.S. funding of science has declined in recent years; Dr. Insel talks about the need for research and development related to mental illness.

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What Caused This to Happen?

Dr. Insel discusses the idea that chance may have as much to do with the development of mental illness as do genetic and environmental factors.

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Best of 2014

Dr. Insel offers an overview of his top ten mental health stories for 2014.

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Lost in Translation

Drug testing in mice has been a poor guide to effectiveness in humans; Dr. Insel talks about the need for research approaches that can more reliably guide medication development.

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Can We Prevent Psychosis?

In his blog, Dr. Insel discusses the need for early and accurate prediction of psychosis risk and for effective preventive treatments.

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P-Hacking

In his blog, Dr. Insel talks about the reasons for problems with reproducibility in research, among them flawed use of statistical analysis.

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Depression, Daughters, and Cellular Aging

An early sign of depression risk may provide not only a biomarker for depression but a clue to the relationship between depression and risk for medical illnesses; Dr. Insel blogs.

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Atonement

In his blog for Mental Illness Awareness Week, Dr. Insel talks about the complexity of mental disorders and the need for scientists, clinicians, patients, and families to work together in searching for better treatment.

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Ketamine

Ongoing research is investigating the long-term efficacy and safety of the anesthetic drug ketamine, which studies have shown can rapidly lift depressive symptoms; Dr. Insel talks about the status of ketamine in his blog.

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