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Director’s Blog

Mortality and Mental Disorders

A recent paper reports findings on the reduction in life expectancy among people with mental illness relative to the general population; Dr. Insel discusses the magnitude and reasons for this excess mortality.

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Immune to Stress?

We tend to assume that the secrets to understanding individual differences in resilience to stress must be sought in the brain. Now, findings in mice suggest that the peripheral immune system might play a pivotal role.

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Precision Medicine for Mental Disorders

In his latest blog, Dr. Insel discusses precision medicine, which is the new hot topic in research and what it means for mental health.

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The Ignorance Project

At the recent World Economic Forum, brain research was a hot topic; Dr. Insel reports on statistics presented at the conference that inspire optimism that progress can be made on difficult problems, including mental disorders.

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Funding Science

Relative to other countries, U.S. funding of science has declined in recent years; Dr. Insel talks about the need for research and development related to mental illness.

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What Caused This to Happen?

Dr. Insel discusses the idea that chance may have as much to do with the development of mental illness as do genetic and environmental factors.

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Best of 2014

Dr. Insel offers an overview of his top ten mental health stories for 2014.

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Lost in Translation

Drug testing in mice has been a poor guide to effectiveness in humans; Dr. Insel talks about the need for research approaches that can more reliably guide medication development.

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Can We Prevent Psychosis?

In his blog, Dr. Insel discusses the need for early and accurate prediction of psychosis risk and for effective preventive treatments.

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P-Hacking

In his blog, Dr. Insel talks about the reasons for problems with reproducibility in research, among them flawed use of statistical analysis.

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