News and Multimedia from 2006 Featuring DNBBS

Experience Sculpts Brain Circuitry to Build Resiliency to Stress

Press Release • December 21, 2006

It’s long been known that experiencing control over a stressor immunizes a rat from developing a depression-like syndrome when it later encounters stressors that it can’t control.

Receptor Helps Neurons Grow in Right Direction

Science Update • December 12, 2006

Researchers have discovered a receptor for a key protein that helps guide certain nerve cells into the correct position as the nervous system develops — a vital part of a process that enables the brain to receive sensory input from the environment and to send messages to the rest of the body via the spinal cord.

Mouse Model May Reveal Anxiety Gene, Marker for Antidepressant Failure

Science Update • November 09, 2006

Studies of a new mouse model suggest that a specific gene variation plays a role in the development of anxiety disorders and in resistance to common medications for anxiety and depression.

Gene Linked to Autism in Families with More Than One Affected Child

Press Release • October 17, 2006

A version of a gene has been linked to autism in families that have more than one child with the disorder. Inheriting two copies of this version more than doubled a child’s risk of developing an autism spectrum disorder, scientists supported by NIMH and NICHD have discovered.

Receptor Knockout Yields an Adventurous Mouse

Press Release • August 01, 2006

Mice altered to lack a particular type of receptor in the brain’s executive hub are more prone to go where normal mice fear to tread, NIMH funded scientists have discovered.

Males with Autism Have Fewer Cells in Brain’s Emotional Memory Hub

Science Update • July 26, 2006

Males with autism have fewer cells in a part of the brain that has a key role in emotion and memory, according to NIMH-funded researchers at the University of California, Davis.

New Tool Can Boost or Block the Body’s Protective Inner Barriers

Press Release • July 13, 2006

A team of experts funded by NIH has developed a chemical tool that allows scientists to manipulate control of the passage of substances through the barriers between blood and the tissues of every organ — from the brain, lungs, and heart to the organs of the immune system.

Properly Timed Light, Melatonin Lift Winter Depression by Syncing Rhythms

Science Update • May 01, 2006

Most Seasonal Affective Disorder (SAD) symptoms stem from daily body rhythms that have gone out-of-sync with the sun, a NIMH-funded study has found.

Gene Influences Antidepressant Response

Press Release • March 15, 2006

Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at NIH has discovered. Having two copies of one version of a gene that codes for a component of the brain’s mood―regulating system increased the odds of a favorable response to an antidepressant by up to 18 percent, compared to having two copies of the other, more common version.

Depression Model Leaves Mice with Molecular Scar

Press Release • February 27, 2006

In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring “molecular scar” in its brain that could help to explain why depression is so difficult to cure, suggest researchers funded by NIMH.

Lithium Blocks Enzyme To Help Cells’ Clocks Keep On Tickin’

Science Update • February 17, 2006

NIMH-funded researchers have discovered how lithium likely fixes body clocks gone awry, stabilizing sleep-wake cycles and other daily rhythms disturbed along with mood in bipolar disorder.

Nobelist Discovers Antidepressant Protein in Mouse Brain

Press Release • January 06, 2006

A protein that seems to be pivotal in lifting depression has been discovered by a Nobel Laureate researcher funded by NIMH.

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