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News and Multimedia from 2006 Featuring DNBBS

Experience Sculpts Brain Circuitry to Build Resiliency to Stress

Press Release

It’s long been known that experiencing control over a stressor immunizes a rat from developing a depression-like syndrome when it later encounters stressors that it can’t control.

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Receptor Helps Neurons Grow in Right Direction

Science Update

Researchers have discovered a receptor for a key protein that helps guide certain nerve cells into the correct position as the nervous system develops — a vital part of a process that enables the brain to receive sensory input from the environment and to send messages to the rest of the body via the spinal cord.

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Mouse Model May Reveal Anxiety Gene, Marker for Antidepressant Failure

Science Update

Studies of a new mouse model suggest that a specific gene variation plays a role in the development of anxiety disorders and in resistance to common medications for anxiety and depression.

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Gene Linked to Autism in Families with More Than One Affected Child

Press Release

A version of a gene has been linked to autism in families that have more than one child with the disorder. Inheriting two copies of this version more than doubled a child’s risk of developing an autism spectrum disorder, scientists supported by NIMH and NICHD have discovered.

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Receptor Knockout Yields an Adventurous Mouse

Press Release

Mice altered to lack a particular type of receptor in the brain’s executive hub are more prone to go where normal mice fear to tread, NIMH funded scientists have discovered.

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Males with Autism Have Fewer Cells in Brain’s Emotional Memory Hub

Science Update

Males with autism have fewer cells in a part of the brain that has a key role in emotion and memory, according to NIMH-funded researchers at the University of California, Davis.

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New Tool Can Boost or Block the Body’s Protective Inner Barriers

Press Release

A team of experts funded by NIH has developed a chemical tool that allows scientists to manipulate control of the passage of substances through the barriers between blood and the tissues of every organ — from the brain, lungs, and heart to the organs of the immune system.

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Properly Timed Light, Melatonin Lift Winter Depression by Syncing Rhythms

Science Update

Most Seasonal Affective Disorder (SAD) symptoms stem from daily body rhythms that have gone out-of-sync with the sun, a NIMH-funded study has found.

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Gene Influences Antidepressant Response

Press Release

Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at NIH has discovered. Having two copies of one version of a gene that codes for a component of the brain’s mood―regulating system increased the odds of a favorable response to an antidepressant by up to 18 percent, compared to having two copies of the other, more common version.

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Depression Model Leaves Mice with Molecular Scar

Press Release

In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring “molecular scar” in its brain that could help to explain why depression is so difficult to cure, suggest researchers funded by NIMH.

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Lithium Blocks Enzyme To Help Cells’ Clocks Keep On Tickin’

Science Update

NIMH-funded researchers have discovered how lithium likely fixes body clocks gone awry, stabilizing sleep-wake cycles and other daily rhythms disturbed along with mood in bipolar disorder.

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Nobelist Discovers Antidepressant Protein in Mouse Brain

Press Release

A protein that seems to be pivotal in lifting depression has been discovered by a Nobel Laureate researcher funded by NIMH.

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