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Recent News and Multimedia Featuring DNBBS

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Powered-Up Probe ID’s Schizophrenia Genes That Stunt Brain Development

Science Update

Scientists have pinpointed several schizophrenia-related gene variants that alter expression of other genes in illness-implicated circuitry of the human brain.

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Circuitry for Fearful Feelings, Behavior Untangled in Anxiety Disorders

Science Update

Untangling the brain circuitry of fearful feelings from that underlying defensive behaviors is key to improving treatments for anxiety disorders, argue two leading experts.

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Designer Agent Blocks Pain in Mice Without Morphine’s Side Effects

Science Update

Scientists have synthesized a molecule with a unique profile of highly specific pain-relieving properties and demonstrated its efficacy in mice.

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How “Quickly Forgotten” Early Life Experiences Mature the Brain

Science Update

Brain memory circuitry’s keen sensitivity to experience during an early critical period enables long-term memory ability to develop through practice.

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Tapping Crowd-Sourced Data Unearths a Trove of Depression Genes

Press Release

Scientists have discovered 15 genome sites – the first ever – linked to depression in people of European ancestry. But – in a twist – the researchers didn’t have to sequence anyone’s genes! Instead, they analyzed data already shared by people who had purchased their own genetic profiles via an online service and elected to participate in its research option.

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Ketamine Lifts Depression via a Byproduct of its Metabolism

Press Release

A chemical byproduct, or metabolite, created as the body breaks down likely holds the secret to its rapid antidepressant action .

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Circuit for Experience-Informed Decision-Making ID’d in Rats

Press Release

Scientists have discovered secrets of how the brain recalls experiences of being in a particular location in making informed choices.

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Schizophrenia’s Strongest Known Genetic Risk Deconstructed

Press Release

Versions of a gene linked to schizophrenia may trigger runaway pruning of the teenage brain’s still-maturing communications infrastructure.The gene switched on more in people with the suspect versions, who faced a higher risk of developing the disorder.

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Blog, Video Spotlight NIMH Neuroscience Trainee

Science Update

A recent NIH Director’s Blog and Lab TV video feature a young neuroscientist whose discoveries as a graduate student – about a key maternal behavior – were supported, in part, by a NIMH training grant.

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Our Brain’s Secrets to Success?

Press Release

We owe our success -- both as a species and as individuals – to uniquely human brain wiring that is just now beginning to be understood, thanks to the BRAIN Initiative and the Human Connectome Project.

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