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Recent News and Multimedia Featuring DNBBS

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Circuit for Experience-Informed Decision-Making ID’d in Rats

Press Release

Brain circuitry and decision making for rats - thumbnail

Scientists have discovered secrets of how the brain recalls experiences of being in a particular location in making informed choices.

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Schizophrenia’s Strongest Known Genetic Risk Deconstructed

Press Release

C4 tower in genomic skyline thumb

Versions of a gene linked to schizophrenia may trigger runaway pruning of the teenage brain’s still-maturing communications infrastructure.The gene switched on more in people with the suspect versions, who faced a higher risk of developing the disorder.

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Blog, Video Spotlight NIMH Neuroscience Trainee

Science Update

Marlin - Lab TV video - thumb

A recent NIH Director’s Blog and Lab TV video feature a young neuroscientist whose discoveries as a graduate student – about a key maternal behavior – were supported, in part, by a NIMH training grant.

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Our Brain’s Secrets to Success?

Press Release

Smarts, life satisfaction, income and education levels – and other measures of success – were correlated with increased connectivity between certain areas of the brain while at rest.  These parts of the brain (yellow, red, brown) talked with each other more while higher-scoring participants weren’t doing anything in particular. Picture shows composite data from functional magnetic resonance imaging scans.

We owe our success -- both as a species and as individuals – to uniquely human brain wiring that is just now beginning to be understood, thanks to the BRAIN Initiative and the Human Connectome Project.

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A Patient’s Budding Cortex -- in a Dish?

Press Release

Neurons and supporting cells in the spheroids form layers and organize themselves according to the architecture of the developing human brain and network with each other.  Source: Sergiu Pasca, M.D., Stanford University

Scientists have perfected mini cultured 3-D structures that grow and function much like the outer mantle – the key working tissue, or cortex – of the brain of the person from whom they were derived.

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GTEx Findings Reveal New Insights into how DNA Differences Influence Gene Activity, Disease Susceptibility

Press Release

Genotype-Tissue Expression Project chart shows locations for liver, heart and brain tissue within the human body

Data resource begins to reveal how genetic variability influences key tissues in health and disease.

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Brain Circuitry for Positive vs Negative Memories Discovered in Mice

Press Release

Neuronal projections encoding negative (red) and positive (green) associations

Neuroscientists have discovered brain circuitry for encoding positive and negative learned associations in mice.

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NIH Announces Follow that Cell Challenge Finalists

Press Release

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NIH has selected 5 prize winners and 11 finalists in Phase 1 of its Follow that Cell Challenge, which aims to develop new ways to predict the behavior and function of a single cell in complex tissue over time.

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Disorders Share Risk Gene Pathways for Immune, Epigenetic Regulation

Science Update

double helix

Risk genes for different mental disorders work through same pathways

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Brain Recalls Old Memories via New Pathways

Press Release

Memory circuit shift

Brain retrieval circuitry shifts as fear memory ages

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