News and Multimedia Featuring DNBBS
- Ketamine Cousin Rapidly Lifts Depression Without Side Effects
- Science Update • May 23, 2013
NMDA or glutamate receptor modulators as antidepressants have come of age. Human clinical studies demonstrated that ketamine can ward off depressive symptoms within 2 hours of administration and last for several days. Yet serious side effects are attached to this drug, including excessive sleepiness, hallucinations, and substance abuse behavior.
- Taming Suspect Gene Reverses Schizophrenia-like Abnormalities in Mice
- Press Release • May 22, 2013
Scientists have reversed behavioral and brain abnormalities in adult mice that resemble some features of schizophrenia, by restoring normal expression to the gene Neuregulin1, which makes a protein important for brain development.
- Suppressing Protein May Stem Alzheimer’s Disease Process
- Press Release • April 25, 2013
Scientists funded by the National Institutes of Health have discovered a potential strategy for developing treatments to stem the disease process in Alzheimer’s disease, by blocking activity of a little-known regulator protein called CD33.
- Dr. Michelle Freund, NIMH Project Officer on the significance of CLARITY
- Video • April 11, 2013
Project officer Michelle Freund, Ph.D., of the NIMH Division of Neuroscience and Basic Behavioral Science, explains the significance of CLARITY, a breakthrough method for analyzing the brain. - Fat-free See-through Brain Bares All
- Press Release • April 10, 2013
Scientists can now study the brain’s finer workings, while preserving its 3-D structure and integrity of its circuitry using a breakthrough method, called CLARITY, that substitutes a clear gel for fat that normally holds the brain’s working components in place, making its normally opaque and impenetrable tissue see-through and permeable.
- Developing Male Brain Exposed to Less Stress-Protective Protein
- Science Update • March 12, 2013
Why are rates of schizophrenia and autism higher in males? New evidence implicates an enzyme expressed in the placenta that helps protect the developing fetal brain from adverse effects of maternal stress early in pregnancy.
- NIMH’s Dr. Aleksandra Vicentic: Sleep Brain Wave Key to Conquering Fear Memories
- Science Update • March 08, 2013
An NIMH-funded research study in rats identifies a specific group of cells in the brainstem whose activation during rapid eye movement (REM) sleep helped in eradicating unwanted memories, paving the way for future therapeutics for these disorders.
- Five Major Mental Disorders Share Genetic Roots
- Science Update • March 01, 2013
Five major mental disorders share some of the same genetic risk factors, the largest genome-wide study of its kind has found.
- Different Genes, Same Risk Pathway in Schizophrenia
- Science Update • January 02, 2013
Work by NIMH-supported scientists illustrates the variability of the genes and biology underlying illnesses like schizophrenia.
- Stress-Resilience/Susceptibility Traced to Neurons in Reward Circuit
- Press Release • December 12, 2012
Researchers, for the first time, have instantly switched depression-like states on-and-off in mice by tweaking the firing pattern of neurons in the brain’s reward circuit.
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