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News and Multimedia Featuring DNBBS

NIH Announces First Wave of Funding for BRAIN Initiative Research

Science Update

BRAIN Initiative

Calling it “the beginning of an ambitious journey”, the National Institutes of Health announced its first wave of grants in support of the BRAIN Initiative.

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BRAIN Initiative as Moonshot

Video.

NIH director Francis Collins, M.D., discusses some of the 58 projects funded in the first wave of grants awarded by the NIH under the BRAIN Initiative. He spoke at a press conference announcing the awards, September 30, 2014.

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Much more extraordinary than anything we can imagine

Video.

NIMH director Thomas Insel, M.D., discussed the promise of brain science over the next decade at a NIH press conference announcing the launch of 58 projects under the BRAIN Initiative, September 30, 2014.

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Magnetic Stimulation Boosts Human Memory, Network Connectivity

Science Update

fMRI memory circuits

Scientists have improved memory for associations between faces and words by electromagnetically stimulating neural connections in a brain network.

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Suspect Gene Corrupts Neural Connections

Press Release

Synapses in mature iPSC cortex neuron Hongjun Song iPSC

Researchers have shown in patients’ cells how a rare mutation in a suspect gene disrupts the expression of dozens of other genes underlying neural connections.

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Follow that Cell

Press Release

SCAP Challenge graphic thumbnail

The National Institutes of Health is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time.

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Schizophrenia’s Genetic “Skyline” Rising

Press Release

Schizophrenia genetics Manhattan plots, 2011, 2014

The largest genomic dragnet of any psychiatric disorder to date has unmasked 108 chromosomal sites harboring inherited variations in the genetic code linked to schizophrenia, 83 of which had not been previously reported.

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Common Gene Variants Account for Most Genetic Risk for Autism

Press Release

Buxbaum Autism Architecture Chart

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

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Shining a Light on Memory

Press Release

Malinow Engineering Memory Rat

Using a flash of light, scientists have inactivated and then reactivated a memory in genetically engineered rats. The findings – the first cause-and-effect evidence that strengthened connections between neurons are the stuff of memory – add to mounting evidence that the brain represents a memory by forming assemblies of neurons with strengthened connections.

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Jump-starting Natural Resilience Reverses Stress Susceptibility

Press Release

Antidepressant effects

Scientists have traced vulnerability to depression-like behaviors to out-of-balance neuronal electrical activity and made mice resilient by reversing it.

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