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News and Multimedia Featuring DNBBS

A Patient’s Budding Cortex -- in a Dish?

Press Release

Neurons and supporting cells in the spheroids form layers and organize themselves according to the architecture of the developing human brain and network with each other.  Source: Sergiu Pasca, M.D., Stanford University

Scientists have perfected mini cultured 3-D structures that grow and function much like the outer mantle – the key working tissue, or cortex – of the brain of the person from whom they were derived.

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GTEx Findings Reveal New Insights into how DNA Differences Influence Gene Activity, Disease Susceptibility

Press Release

Genotype-Tissue Expression Project chart shows locations for liver, heart and brain tissue within the human body

Data resource begins to reveal how genetic variability influences key tissues in health and disease.

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Brain Circuitry for Positive vs Negative Memories Discovered in Mice

Press Release

Neuronal projections encoding negative (red) and positive (green) associations

Neuroscientists have discovered brain circuitry for encoding positive and negative learned associations in mice.

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NIH Announces Follow that Cell Challenge Finalists

Press Release

SCAP Challenge graphic thumbnail

NIH has selected 5 prize winners and 11 finalists in Phase 1 of its Follow that Cell Challenge, which aims to develop new ways to predict the behavior and function of a single cell in complex tissue over time.

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Disorders Share Risk Gene Pathways for Immune, Epigenetic Regulation

Science Update

double helix

Risk genes for different mental disorders work through same pathways

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Brain Recalls Old Memories via New Pathways

Press Release

Memory circuit shift

Brain retrieval circuitry shifts as fear memory ages

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Largest Autism Gene Dragnet Fingers 33 Prime Suspects

Science Update

Joseph Buxbaum, Ph.D.

Many patients with psychosis develop health risks associated with premature death early in the course of their mental illness, researchers have found.

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NIH Announces First Wave of Funding for BRAIN Initiative Research

Science Update

BRAIN Initiative

Calling it “the beginning of an ambitious journey”, the National Institutes of Health announced its first wave of grants in support of the BRAIN Initiative.

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BRAIN Initiative as Moonshot

Video.

NIH director Francis Collins, M.D., discusses some of the 58 projects funded in the first wave of grants awarded by the NIH under the BRAIN Initiative. He spoke at a press conference announcing the awards, September 30, 2014.

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Much more extraordinary than anything we can imagine

Video.

NIMH director Thomas Insel, M.D., discussed the promise of brain science over the next decade at a NIH press conference announcing the launch of 58 projects under the BRAIN Initiative, September 30, 2014.

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