This program supports interdisciplinary neuroscience research aimed at identifying molecular and cellular mechanisms underlying the behavioral actions of psychotherapeutic drugs in model systems. The program focuses on identifying novel targets (genes, molecules) for therapeutic intervention in mental disorders using appropriate models and measures relevant to neuropsychiatric disorders. Areas of interest include:
- Elucidating molecular and cellular mechanisms responsible for the differential behavioral effects of acute and chronic drugs by genes, sex, age, and environment.
- Identifying the neural circuitry mediating the behavioral effects of psychotherapeutic drugs.
- Developing preclinical models and measures of fundamental processes altered in emotional and cognitive disorders.
- Developing genetic approaches and imaging techniques to reveal critical molecules and signaling cascades responsible for the behavioral effects of drugs.
Applicants are strongly encouraged to discuss their proposals with the institute contact listed below prior to the submission of their applications to ascertain that their proposed work is aligned with NIMH funding priorities.
Lois Winsky, Ph.D.
6001 Executive Boulevard, Room 7185, MSC 9641