News and Multimedia from 2009 Featuring DSIR

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Substance Use Associated with Low Response to Depression Treatment Among Teens
Science Update • December 09, 2009
teen boy asleep with book

Depressed teens who report low levels of impairment related to drug or alcohol use tended to respond better to depression treatment than depressed teens with higher levels substance-related impairment, according to an analysis of data from the NIMH-funded Treatment of SSRI-Resistant Depression in Adolescents (TORDIA) study. However, it is unclear whether less substance-related impairment allowed for better response to depression treatment, or if better treatment response led to less substance-related impairment. The study was published in the December 2009 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

Parent Training Complements Medication for Treating Behavioral Problems in Children with Pervasive Developmental Disorders
Press Release • November 20, 2009
mother and son hugging

Treatment that includes medication plus a structured training program for parents reduces serious behavioral problems in children with autism and related conditions, according to a study funded by the National Institute of Mental Health (NIMH). The study, which was part of the NIMH Research Units on Pediatric Psychopharmacology (RUPP) Autism Network, was published in the December 2009 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

Long-term Depression Treatment Leads to Sustained Recovery for Most Teens
Science Update • November 18, 2009
man and teen talking

Long-term treatment of adolescents with major depression is associated with continuous and persistent improvement of depression symptoms in most cases, according to the most recent analysis of follow-up data from the NIMH-funded Treatment of Adolescents with Depression Study (TADS). The report, along with a commentary compiling the take-home messages of the study, was published in the October 2009 issue of the American Journal of Psychiatry.

NIH Encourages Depressed Moms to Seek Treatment for Themselves
Science Update • November 13, 2009
woman holding child while sitting on a chair

Numerous studies have suggested that depression runs in families. Children of depressed parents are 2–3 times as likely to develop depression as compared to children who do not have a family history of the disorder. Other studies have shown that remission of depression in mothers is associated with improvements in psychiatric symptoms in their children. Despite all signs encouraging mothers to prioritize their own mental health, many suffer from untreated depression while managing treatment for their children’s emotional or behavioral problems.

Significant Weight Gain, Metabolic Changes Associated with Antipsychotic Use in Children
Science Update • October 27, 2009
medication

Many children and adolescents who receive antipsychotic medications gain a significant amount of weight and experience metabolic changes, according to NIMH-funded research published October 28, 2009, in the Journal of the American Medical Association.

Telephone-based Depression Treatment Program Effective While Cost Efficient
Science Update • October 16, 2009
telephone

Patients who receive structured, telephone-based support to manage their depression gain significant benefits with only moderate increases in health care costs compared to those who receive usual care, according to an NIMH-funded analysis published in the October 2009 issue of the Archives of General Psychiatry.

PTSD Treatment Efforts for Returning War Veterans to be Evaluated
Science Update • September 30, 2009
man and woman in individual therapy

Joan Cook, Ph.D., of Yale University and colleagues have been awarded funds from the American Recovery and Reinvestment Act of 2009 to evaluate the implementation of two evidence-based psychotherapies for treating post traumatic stress disorder (PTSD) among veterans. The grant addresses the NIH Challenge Grant topic “Strategies to Support Uptake of Interventions within Clinical Community and Settings.”

New Approach to Reducing Suicide Attempts Among Depressed Teens
Science Update • September 29, 2009
young man looking out window

A novel treatment approach that includes medication plus a newly developed type of psychotherapy that targets suicidal thinking and behavior shows promise in treating depressed adolescents who had recently attempted suicide, according to a treatment development and pilot study funded by the National Institute of Mental Health (NIMH). The study, described in three articles, was published in the October 2009 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

Economic Analysis Estimates Cost of Providing Comprehensive Mental Health Care Following Disasters
Science Update • August 11, 2009
adult hugging child in lake

Making evidence-based mental health services accessible to everyone in a disaster-stricken area would have substantial public health benefits, according to a statistical model developed by NIMH-funded researchers.

Combination Treatment for Psychotic Depression Holds Promise
Science Update • August 07, 2009

A combination of an atypical antipsychotic medication and an antidepressant known as a selective serotonin reuptake inhibitor (SSRI) may be more effective in treating psychotic depression than an atypical antipsychotic alone, according to results from an NIMH-funded clinical study.

Youth with Autism Coming of Age: New NIMH Study Will Focus on Transitions in Service Use and Coverage
Science Update • August 07, 2009
young man looking out window

The transition from teen to young adult involves many highly anticipated rites of passage. However, for youths with developmental disorders, coming of age may signal the sudden end of coverage for education and training programs, health insurance, and youth-oriented services.

Major NIMH Research Project to Test Approaches to Altering the Course of Schizophrenia
Press Release • July 21, 2009

The National Institute of Mental Health (NIMH) is launching a large-scale research project to explore whether using early and aggressive treatment, individually targeted and integrating a variety of different therapeutic approaches, will reduce the symptoms and prevent the gradual deterioration of functioning that is characteristic of chronic schizophrenia.

Evidence-Based Prevention is Goal of Largest Ever Study of Suicide in the Military
Press Release • July 16, 2009

The National Institute of Mental Health (NIMH) has announced that an interdisciplinary team of four research institutions will carry out the largest study of suicide and mental health among military personnel ever undertaken, with $50 million in funding from the U.S. Army. Study investigators aim to move quickly to identify risk and protective factors for suicide among soldiers and provide a science base for effective and practical interventions to reduce suicide rates and address associated mental health problems.

Re-shaping Negative Thoughts Shields At-Risk Teens from Depression
Science Update • June 09, 2009
teen boy with his head down

At-risk teens exposed to a program that teaches them to counteract their unrealistic and overly negative thoughts experienced significantly less depression than their peers who received usual care, NIMH-funded researchers have found. However, the cognitive behavioral prevention program failed to similarly help adolescents prone to the mood disorder if their parents were currently depressed.

Searching for Risk Factors of Suicidal Events During Antidepressant Treatment
Science Update • May 29, 2009

A new set of analyses of the NIMH-funded Treatment for Adolescents with Depression Study (TADS) were conducted to better understand what may predict the development of suicidal events during treatment. The analyses, which were published in the May 2009 issue of the Journal of Clinical Psychiatry, showed that youths with suicidal thoughts and more severe depression prior to treatment were at higher risk for suicidal events while undergoing treatment.

Recovery Funds Will Support Evaluation of Suicide Prevention Training
Press Release • May 22, 2009

The National Institute of Mental Health (NIMH) is using funds from the American Recovery and Reinvestment Act to provide grant support for the completion of a project under way to evaluate the effectiveness of a new training program for telephone crisis counselors at suicide hotline centers.

ADHD Medication Treatment Associated with Higher Academic Performance in Elementary School
Science Update • April 27, 2009
Doctor with young boy

Children with attention deficit hyperactivity disorder (ADHD) who take medication to treat the condition tend to do better in math and reading compared to their peers who also have ADHD but do not take medication, according to data from a national survey. The NIMH-funded study was published in the May 2009 issue of Pediatrics.

Use of Antipsychotics in Alzheimer’s Patients May Lead to Detrimental Metabolic Changes
Science Update • April 15, 2009
Woman looking out a window (photograph).

Atypical antipsychotic medications are associated with weight gain and other metabolic changes among patients with Alzheimer’s disease, according to a recent analysis of data from the NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness—Alzheimer’s Disease (CATIE-AD) study. The study was published online ahead of print April 15, 2009, in the American Journal of Psychiatry.

Short-term Intensive Treatment Not Likely to Improve Long-term Outcomes for Children with ADHD
Science Update • March 26, 2009

Short-term Intensive Treatment Not Likely to Improve Long-term Outcomes for Children with ADHD

Premature Birth Risk Higher for Pregnant Women Taking SSRIs or Suffering from Untreated Depression
Science Update • March 19, 2009

Untreated major depression, as well as the use of antidepressant medications, may increase the risk for premature (preterm) birth, but the risk of other problems in fetuses such as breathing, gastrointestinal, or motor problems, may not be increased, according to a study of pregnant women published online ahead of print March 15, 2009, in the American Journal of Psychiatry.

Suicidal Thinking May Be Predicted Among Certain Teens with Depression
Science Update • February 17, 2009

Certain circumstances may predict suicidal thinking or behavior among teens with treatment-resistant major depression who are undergoing second-step treatment, according to an analysis of data from an NIMH-funded study. The study was published online ahead of print February 17, 2009, in the American Journal of Psychiatry.

Health Care Costs Much Higher for Older Adults with Depression Plus Other Medical Conditions
Science Update • February 13, 2009

Medicare participants who have diabetes or congestive heart failure as well as depression have significantly higher health care costs than their counterparts who do not have co-existing depression, according to a recent NIMH-funded analysis published online ahead of print January 16, 2009, in the Journal of the American Geriatric Society.

Getting Closer to Personalized Treatment for Teens with Treatment-resistant Depression
Science Update • February 11, 2009

Some teens with treatment-resistant depression are more likely than others to get well during a second treatment attempt of combination therapy, but various factors can hamper their recovery, according to an NIMH-funded study published online ahead of print February 4, 2009, in the Journal of the American Academy of Child and Adolescent Psychiatry.

Adolescents with Depression Not Harmed in Studies Using Placebo
Science Update • January 15, 2009

Teens with depression who initially are randomly assigned to placebo treatment (inactive pill) during a trial are no more likely to experience harm or have a diminished response to subsequent active treatments than teens who are initially randomized to active treatment, according to an analysis of data from the NIMH-funded Treatment for Adolescents with Depression Study (TADS).


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