Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study
The NIMH-funded Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study was conducted to determine the effectiveness of different treatments for people with major depression who have not responded to initial treatment with an antidepressant. This is the largest and longest study ever conducted to evaluate depression treatment. This page provides information about the study.
Questions and Answers
News about the STAR*D Study
- Science Update (June 7, 2007): Gene Variants Linked to Suicidal Thoughts in Some Men Starting Antidepressant Treatment
- Science Update (May 1, 2007): In Second Try to Treat Depression, Cognitive Therapy Generally as Effective as Medication
- Other studies conducted by clinical investigators from the STAR*D study team include: