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Anxiety Disorders

Featured Studies

Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.

  • PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX.
    Evaluation study. Objective: Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors that respond to glutamate by activating proteins inside nerve cells that affect cell metabolism, thereby fine-tuning the signals sent between cells to maintain balance in neuronal activity. Ages 18-55. Location in Bethesda, MD.
  • A Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults.
    Evaluation study. Background: - An interview called the Schedule for Affective Disorders and Schizophrenia for School Age Children Present and Lifetime version (K-SADS-PL) is used to identify mental health problems among children and younger teens. Ages 18-80. Location in Bethesda, MD.
  • Anxiety and Recurrent Abdominal Pain in Children.
    Interventional study. This study aims to determine whether citalopram is a useful, well-tolerated, and safe treatment for children and adolescents ages 7 to 18 years with functional abdominal pain. Ages 7-18. Location in Columbus, OH.
  • Preventing Anxiety Disorders in Youth.
    Interventional study. This study will determine the effectiveness of a cognitive behavioral therapy program in preventing anxiety disorders in at-risk children. Ages 8-12. Location in Baltimore, MD.
  • The Psychobiology of Childhood Temperament.
    Evaluation study. The purpose of this study is to use brain imaging technology to examine brain changes that occur in children when they are exposed to various kinds of emotional tasks and to determine if these changes are related to the child's temperament. Ages 7-25. Locations in Bethesda, MD; College Park, MD.
  • Child and Adolescent Anxiety Disorders (CAMS).
    Interventional study. This 9-month study will compare the effectiveness of the medication sertraline (Zoloft®), cognitive-behavioral therapy, the combination of these treatments, and placebo for youth with anxiety disorders. Ages 7-17.
  • Brain Changes in Fear.
    Evaluation study. The purpose of this study is to use brain imaging technology to investigate brain changes in people exposed to predictable versus unpredictable unpleasant stimuli. Ages 18-50. Location in Bethesda, MD.
  • Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers.
    Evaluation study. The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Mood and Anxiety Disorders Program (MAP) at the National Institute of Mental Health (NIMH) and for the collection of natural history data. Ages 3 and over. Location in Bethesda, MD.
  • Brain Tissue Collection for Neuropathological Studies.
    Evaluation study. The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Locations in Bethesda, MD; Washington, DC; Fairfax, VA.

Search ClinicalTrials.gov for other NIH studies on Anxiety Disorders.