Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Near Infrared Spectroscopy in Children With Autism and ADHD.
Evaluation study. Background: - Near-infrared spectroscopy (NIRS) is a functional imaging technique that can be uses light to study brain function while allowing for movement. Ages 4-8. Location in Bethesda, MD.
- Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study).
Interventional study. This study will determine the advantages and disadvantages of adding one of two different types of drugs to stimulant treatment for reducing aggressive behavior in children with attention deficit with hyperactivity disorder (ADHD). Ages 6-12. Locations in Glen Oaks, NY; Stony Brook, NY; San Antonio, TX.
- A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation.
Interventional study. Severe mood dysregulation (SMD) is a very common syndrome in children. Ages 7-17. Location in Bethesda, MD.
- Effectiveness of School- and Home-Based Mental Health Services in Improving Learning and Behavior in Children in Urban Schools.
Interventional study. This study will evaluate the effectiveness of school- and home-based mental health services and training modules in supporting learning and behavior in financially disadvantaged children who live in urban areas. Ages 5-12. Location in Chicago, IL.
- Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will evaluate the effectiveness of a single drug versus a combination of drugs in treating attention deficit hyperactivity disorder in children. Ages 7-14. Location in Los Angeles, CA.
- Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children.
Interventional study. This study will determine the effectiveness of stimulant and nonstimulant medication in treating the symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents. Ages 6-17. Locations in Chicago, IL; New York City, NY.
- A Clinic-Based Prevention Program for Families of Depressed Mothers.
Interventional study. This study will assess the effectiveness of the "Keeping Families Strong" program (KFS) in avoiding or delaying the onset of psychiatric disorders among children with depressed mothers. Ages 8 and over. Location in Baltimore, MD.
- Brain Changes in Children and Adolescents With Behavioral Problems.
Evaluation study. Purpose: This study will examine brain activity in children age 10-18 with disruptive behavior problems, including conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD), compared with children without behavioral problems. Ages 8-18. Location in Bethesda, MD.
- Learn more about Attention Deficit Hyperactivity Disorder (ADHD, ADD)
Attention Deficit Hyperactivity Disorder, ADHD, is one of the most common mental disorders that develop in children. Children with ADHD have impaired functioning in multiple settings, including home, school, and in relationships with peers. If untreated, the disorder can have long-term adverse effects into adolescence and adulthood.
Clinical Research at NIMH
- For opportunities to participate in NIMH research on the NIH campus, visit the patient recruitment Website. Travel and lodging assistance available.