NIMH designed the practical clinical trials to examine changes in both symptoms and functioning to determine whether a treatment improves quality of life, care-giving burden, or use of health services.
These "effectiveness studies" are part of a rigorous effort to discover what therapies work best. The practical clinical trials are:
- CATIE
Clinical Antipsychotic Trials of Intervention Effectiveness - STAR*D
Sequenced Treatment Alternatives to Relieve Depression Study - STEP-BD
Systematic Treatment Enhancement Program for Bipolar Disorder - TADS
Treatment for Adolescents with Depression Study - TORDIA
Treatment of SSRI-resistant Depression in Adolescents study
Participate in NIMH Research
Find opportunities to participate in NIMH research on the NIH campus. Travel and lodging assistance available.
Science News about Clinical Research and Trials
General Information About Clinical Trials
- Clinical Trials and You
- Glossary of Clinical Trial TermsExternal Link: Please review our disclaimer.
- MedlinePlus Clinical Trials Information: English and en Español
- NIH Clinical Research Volunteer Program
- Mental health publications from NIMH
