The NIMH-funded Treatment of SSRI-resistant Depression in Adolescents (TORDIA) study is a multi-site, clinical research study examining treatment options for teens whose depression has not improved after one adequate trial of a selective serotonin reuptake inhibitor (SSRI), a type of antidepressant. This page provides information about the study.
News about the TORDIA study
- Science Update (April 4, 2011): Depressed Teens with History of Abuse Less Likely to Respond to Combination Treatment
- Science Update (December 2, 2010): Teens Who Recover from Hard-to-treat Depression Still at Risk for Relapse
- Science Update (May 26, 2010): Early Treatment Decisions Crucial for Teens with Treatment-resistant Depression
- Science Update (December 9, 2009): Substance Use Associated with Low Response to Depression Treatment Among Teens
- Science Update (February 17, 2009): Suicidal Thinking May Be Predicted Among Certain Teens with Depression
- Science Update (February 11, 2009): Getting Closer to Personalized Treatment for Teens with Treatment-resistant Depression
- Press Release (February 26, 2008): Teens with Treatment-resistant Depression More Likely to Get Better with Switch to Combination Therapy
Related Information
Participate in NIMH Research
Find opportunities to participate in NIMH research on the NIH campus. Travel and lodging assistance available.
Science News about Clinical Research and Trials
General Information About Clinical Trials
- Clinical Trials and You
- Glossary of Clinical Trial TermsExternal Link: Please review our disclaimer.
- MedlinePlus Clinical Trials Information: English and en Español
- NIH Clinical Research Volunteer Program
- Mental health publications from NIMH




