Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Determining Metabolic Effects of Valproate and Antipsychotic Therapy.
Interventional study. This study will determine the metabolic processes responsible for high levels of blood glucose, metabolism disorders, and weight gain in people with schizophrenia who have been treated with antipsychotic medications in combination with valproate. Ages 18-60. Location in St. Louis, MO.
- Safety and Effectiveness of D-Serine in Schizophrenia.
Interventional study. This study will determine whether increasing D-serine within the body will improve negative symptoms and cognitive impairments in people with schizophrenia. Ages 18-60.
- Online Family Support and Education for Schizophrenia.
Interventional study. This study will evaluate the benefits of providing families of schizophrenia patients the opportunity to interact with each other using the Internet. Ages 18-60.
- Daily Intranasal Oxytocin for Childhood-Onset Schizophrenia.
Interventional study. Background: - Oxytocin is a chemical that the brain normally produces. Ages 10-99. Location in Bethesda, MD.
- Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography.
Evaluation study. Background: - Some illnesses, such as schizophrenia, have effects on brain cells called dopamine receptors, which are required for normal brain function. Ages 18-90. Location in Bethesda, MD.