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Adults: Anxiety Disorders

Join a Research Study: Anxiety Disorders

Brain Changes in Fear and Anxiety

The purpose of these research studies is to better understand how the brain and body work in individuals with anxiety disorders.

Research Participation Includes: One outpatient testing session performing computer tasks during a brain scan (functional Magnetic Resonance Imaging (fMRI). During the session, you will be exposed to unpleasant stimuli.  Researchers will assess brain and body responses to task performance reviewing brain imaging (fMRI) and physiological changes (e.g. heart rate) that occur when participants feel anxious.

Who Can Participate: Adults between the ages of 18-50 with generalized anxiety disorder, social anxiety disorder or a panic disorder. Eligible participants must be in good physical health, not currently on any psychotropic medications or other medications that may interfere with the study, and be free of a history of any additional psychiatric disorders.

This study is conducted at the Eligible NIH Clinical Center in Bethesda, Maryland . The one testing session lasts up to 2.5 hours. There is no cost to participate and compensation is provided.

First Steps to Join a Study: Learn study details, be pre-screened for eligibility, and consent to participate.  Refer to study 02-M-0321.

To find out if you qualify, email NIMH or call 1-888-644-2694 (1-888-NIH-ANXI) [TTY: 1-866-411-1010].

Join a Research Study: Anxiety Disorders

Generalized Anxiety Disorder and Social Anxiety Disorder: Their impact on the processing of social emotional information and instrumental learning

If you consider yourself to experience more anxiety or are shyer than those around you or have been diagnosed with generalized anxiety disorder or social anxiety disorder, you may be able to participate in this study examining how the brain responds to and analyzes emotional events.

Our goal is to understand what is special about the brain response to emotional events in people with anxiety disorders. We assess brain responses with both computer tasks and brain imaging (functional Magnetic Resonance Imaging; fMRI). Healthy volunteers who have no history of psychiatric or major medical illness will also be enrolled in this study.

To find out if you qualify, email NIMH or call 1-888-644-2694 (1-888-NIH-ANXI) [TTY: 1-866-411-1010].

Join a Research Study: Anxiety Disorders

How Cognitive Behavioral Therapy (CBT) May Change Stress Responses

This study seeks to understand how people who struggle with anxiety respond to different stressful situations, and how Cognitive Behavioral Therapy (CBT) may change these responses.

Research Participation Includes: Physical and neurological exams, EKG, blood and urine tests and stress-inducing tasks. Optional Cognitive Behavioral Therapy (CBT) is conducted over 8 outpatient group visits of 1.5 hours each.

Who Can Participate: The study is enrolling adults, aged 18-60, with generalized anxiety disorder, social anxiety disorder or a panic disorder.  Eligibility includes fluency in English, in good health, free of certain medications and without recent drug or alcohol abuse (6 months).

Enrollees will participate in 2-4 outpatient procedural visits of 1.5 hours each and 8 CBT sessions. There is no cost to participate and compensation is provided. Research is conducted at the NIH Clinical Center, Bethesda, MD.

First Steps to Join a Study: Call or email us at 1-888-644-2694 (1-888-NIH-ANXI), TTY: 1-866-411-1010, or anxiety@mail.nih.gov. Learn study details, be pre-screened for eligibility, and consent to participate. Refer to study 03-M-0093.

 
 

To find out if you qualify, email NIMH or call 1-888-644-2694 (1-888-NIH-ANXI) [TTY: 1-866-411-1010].

Join a Research Study: Anxiety Disorders, Bipolar Disorder, Depression

NIMH Family Study of Health and Behavior

The major goal of this study is to examine how mood disorders, anxiety disorders and migraine run in families. We study both genetic and environmental factors that may contribute to these conditions.

We recruit people ages 21 and over with depression, manic-depression, social phobia, panic, generalized anxiety, migraine and people without any of these problems. Participants are interviewed about medical and mental symptoms and problems, their health behavior, social factors and a variety of other measures related to their health and behavior. Family members ages 8 and over will also be asked to participate. Some families will be invited to participate in further studies of biological and genetic factors. 
 

To find out if you qualify, email NIMH or call 1-877-250-1560 [TTY: 1-866-411-1010].

Join a Research Study: Anxiety Disorders

Predictability and Aversive Expectancies in Anxiety Disorders

This study seeks to understand how people who struggle with anxiety respond to different stressful situations. Basic research has identified biological processes that play a key role in fear and anxiety. The present study examines such processes across people with varying levels of anxiety

Research Participation Includes: Exposure to mildly unpleasant events while you complete a computer task. Researchers will assess changes in heart rate, muscle activity, sweat responses and respiration. Participation may also include assessments of your memory and attention span.

Who Can Participate in this Study: This study is enrolling adults, aged 18-60, with generalized anxiety disorder, social anxiety disorder or a panic disorder. Eligible participants must be in good physical health, may not be currently on any psychotropic medications or other medications that may interfere with the study, and free of a history of any additional psychiatric disorders.

This study is conducted at the NIH Clinical Center in Bethesda, Maryland. There are several outpatient study visits up to four hours each.

First Steps to Join a Study:  Learn study details, be pre-screened for eligibility, and consent to participate. Refer to study 03-M-0093.

To find out if you qualify, email NIMH or call 1-888-644-2694 (1-888-NIH-ANXI) [TTY: 1-866-411-1010].