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Adults: Healthy Volunteers

Join a Research Study: Healthy Volunteers

Attention and Memory Research Study

This research study seeks to understand if two commonly prescribed medications affect attention and anxiety while performing computer-based tasks. The study involves one assessment visit and two outpatient visits.

The study is enrolling healthy participants ages 18-50. You may be eligible if you no current psychiatric disorder and are free of certain medical conditions.

You may not be eligible is you are pregnant or nursing, have heart disease, neurological disease, certain mental health disorders, or any health problems that would interfere with the study or make it unsafe for you.

Research Participation Includes: Taking one dose of a medication: either Ritalin, Inderal, or placebo (an inactive pill), and performing computer tasks under stressful conditions. Participation may include a brain scan (functional Magnetic Resonance Imaging (fMRI).

The study is conducted at the NIH Clinical Center, America’s research hospital, located on the Metro red line (Medical Center stop) in Bethesda, MD. Parking is provided at no cost. There is no charge for study related procedures and compensation is provided.

First Steps to Participate in Research: Learn study details, ask about your eligibility, and consent to participate. Refer to study no. 14-M-0114. Se habla español.

To find out if you qualify, email NIMH or call 1-301-451-5087 [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Brain and Body Responses to Stress Study

The purpose of this research study is to better understand how the brain and body work when healthy volunteers feel anxious.

Research Participation Includes: 1-4 outpatient visits, computer tasks, and exposure to unpleasant stimuli. Researchers will assess changes in heart rate, muscle activity, sweat responses, and respiration.

Who Can Participate: Healthy volunteers between the ages of 18-50, who have no current psychiatric disorder and are free of certain medical conditions.

You may not be eligible if you are pregnant, have current drug or alcohol abuse, heart disease, neurological disease, or any health problems that would interfere with the study or make it unsafe for you.  

The study is conducted at the NIH Clinical Center in Bethesda, Maryland. The testing sessions may take up to 3 hours. There is no cost to participate and compensation is provided.

First Steps to Participate in Research: Learn study details, ask about your eligibility, and consent to participate.

To find out if you qualify, email NIMH or call 1-301-451-5087 [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Brain Changes in Fear and Anxiety Study

The purpose of this research study is to better understand how the brain and body work when healthy volunteers feel anxious.

Research Participation Includes: 1-3 outpatient visits, computer tasks, and exposure to unpleasant stimuli and a brain scan (functional Magnetic Resonance Imaging (fMRI).

Who Can Participate: Healthy volunteers between the ages of 18-50, who have no current psychiatric disorder and are free of certain medical conditions.

You may not be eligible is you are pregnant, have pacemaker, current alcohol or substance abuse problems, heart disease, neurological disease, or any health problems that would interfere with the study or make it unsafe for you.  

The study is conducted at the NIH Clinical Center in Bethesda, Maryland. The testing sessions will take up to 2.5 hours. There is no cost to participate and compensation is provided.

First Steps to Participate in Research: Learn study details, ask about your eligibility, and consent to participate.

To find out if you qualify, email NIMH or call 1-301-451-5087 [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Brain Imaging and A Study Drugs Effects on Brain Receptors

This research study will evaluate the effects of the experimental medication ketamine on brain receptors in healthy and depressed adults. The study is enrolling healthy participants ages 18-65.  You may be eligible if you free of psychiatric disorders and certain medical conditions.

Research includes 1 to 6 weeks of outpatient procedures: a screening visit, computer tasks, rating scales, neurological testing, two intravenous infusions, a blood draw, brain scans (MEG & fMRI); and may include optional 2-4 overnight stays for a sleep study.

First Steps to Participate include, calling NIMH, learning study details, asking about your eligibility, and consenting to participate.

To find out if you qualify, email NIMH or call 1-877-646-3644 (1-877-MIND-NIH) [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Investigation of how genes and the environment affect brain development

Researchers are enrolling healthy participants, ages 6 and up. This brain development study takes place at the NIH Clinical Center in Bethesda, Maryland. Research participation includes: Brain imaging, blood draw & skin biopsy, and learning & memory tests, and two outpatient visits.

There is no cost to participate and compensation is provided. Transportation assistance/reimbursement is provided. Parental permission is required for minors 18 and under.

To find out if you qualify, email NIMH or call 1-301-496-3334 [TTY: 1-866-411-1010].