Skip to content

Adults: Healthy Volunteers

Join a Research Study: Healthy Volunteers

Attention and Memory Research Study

This research study seeks to understand if two FDA-approved medications affect attention and anxiety while performing computer-based tasks.  The study involves one assessment visit and one outpatient visit. 

The study is enrolling healthy participants ages 18-50.  You may be eligible if you are medically healthy.

You may not be eligible is you are pregnant or nursing, have heart disease, neurological disease, certain mental health disorders, or any health problems that would interfere with the study or make it unsafe for you. 

Research Participation Includes: Taking one dose of a medication: either Ritalin, Inderal, or placebo (an inactive pill), and performing computer tasks under stressful conditions.

The study is conducted at the NIH Clinical Center, America’s research hospital, located on the Metro red line (Medical Center stop) in Bethesda, MD.  Parking is provided at no cost.  There is no charge for study related procedures and compensation is provided. 

First Steps to Participate in Research: Learn study details, be evaluated for eligibility, and consent to participate. Refer to study no. 14-M-0114.  Se habla español.

To find out if you qualify, email NIMH or call 1-800-411-1222 [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Brain and Body Responses to Stress Study

The purpose of this research study is to better understand how the brain and body work when healthy volunteers feel anxious.

Research Participation Includes: Performing computer tasks while being exposed to unpleasant stimuli.  Researchers will assess changes in heart rate, muscle activity, sweat responses, and respiration that occur during exposure to mildly unpleasant events. In addition, we will investigate cognitive changes (e.g. memory, attention) based on your task performance.

Who Can Participate: Healthy volunteers between the ages of 18-50, who have no current psychiatric illness, current drug or alcohol abuse, or major medical illness may be enrolled in this study. Volunteers cannot be pregnant and must also be free of certain medications that may interfere with the study.

The study is conducted at the NIH Clinical Center in Bethesda, Maryland. There are 1 to 4 outpatient visits.  There is no cost to participate and compensation is provided.

First Steps to Join a Study: Learn study details, be pre-screened for eligibility, and consent to participate. Se habla español.

To find out if you qualify, email NIMH or call 1-800-411-1222 [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Brain Changes in Fear and Anxiety Study

The purpose of this research study is to better understand how the brain and body work when healthy volunteers feel anxious.

Research Participation Includes: One outpatient testing session performing computer tasks during a brain scan (functional Magnetic Resonance Imaging (fMRI). During the session, you will be exposed to unpleasant stimuli.  Researchers will assess brain and body responses to task performance reviewing brain imaging (fMRI) and physiological changes (e.g. heart rate) that occur when participants feel anxious.

Who Can Participate: Healthy volunteers between the ages of 18-50, who have no current psychiatric disorder or major medical illness (such as high blood pressure) may be enrolled in this study. Volunteers with a history of past bipolar depression or psychosis may not apply.

The study is conducted at the NUH Clinical Center in Bethesda, Maryland. The one testing sessions lasts up to 2.5 hours. There is no cost to participate and compensation is provided.

First Steps to Participate in Research: Learn study details, be pre-screened for eligibility, and consent to participate. Refer to study 02-M-0321. Se habla español.

To find out if you qualify, email NIMH or call 1-800-411-1222 [TTY: 1-866-411-1010].

Join a Research Study: Healthy Volunteers

Investigation of how genes and the environment affect brain development

Researchers are enrolling healthy participants, ages 6 and up. This brain development study takes place at the NIH Clinical Center in Bethesda, Maryland. Research participation includes: Brain imaging, blood draw & skin biopsy, and learning & memory tests, and two outpatient visits.

There is no cost to participate and compensation is provided. Transportation assistance/reimbursement is provided. Parental permission is required for minors 18 and under.

To find out if you qualify, email NIMH or call 1-301-496-3334 [TTY: 1-866-411-1010].