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Perimenopause: An Observational Study

Join a Research Study: Hormone Therapy-Related Mood Symptoms, Perimenopause-Related Mood Disorders

To find out if you qualify, email NIMH or call 1-301-496-9576 [TTY: 1-866-411-1010].

This is an observational study for perimenopausal depression in women between the ages of 40 and 60. The purpose of this study is to investigate mood and behavioral changes in the time period surrounding and including menopause. Perimenopausal women with depression symptoms and a control group of healthy perimenopausal volunteers will be compared to one another to identify correlates of the occurrence of depression. Additionally, a group of younger pre-perimenopausal women with normal menstrual cycle functioning will be followed through menopause to observe a possible increase of depressive symptoms around the time of menopause. This is an observational study; volunteers who participate will not receive any new or experimental therapies.