Human Brain Collection Core (HBCC)
The purpose of the HBCC is to collect human brain tissue, and hair and blood samples from deceased individuals to learn more about the nervous system and mental disorders. Brain tissue is collected postmortem from individuals diagnosed with schizophrenia, anxiety disorders, suicide, bipolar disorder, depression, Tourette’s Syndrome, drug addictions (e.g., PCP, cocaine, alcohol, heroin), and a variety of neurological disorders, as well as individuals without a history of any neuropsychiatric and neurological disease. Tissue is obtained after death, with the permission of next of kin, or from existing institutions with appropriate transfer of samples via a Material Transfer Agreement (MTA) or other applicable agreement, under the protocols approved by the Institutional Review Board (IRB).
The HBCC distributes well-characterized specimens to investigators approved by a Steering Committee. The HBCC also prepares and analyzes RNA and DNA specimens, collects gene expression and genotyping data, and disseminates the data and other scientific findings to the scientific community. Information gained from the collection of these specimens will lead to better treatments and potential cures for mental and other nervous system disorders.