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Human Brain Collection Core

Selected Publications

  1. Kunii Y, Hyde TM, Ye T, Li C, Kolachana BK, Dickinson D, Weinberger DR, Kleinman JE, Lipska BK. Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder, and genetic associations with t-DARPP-32 expression. Mol Psychiatry, 2012. In press.
  2. Kaalund SS, Newburn EN, Ye T, Ran Tao R, Chao Li C, Deep-Soboslay A, Herman M, Hyde TM, Weinberger DR, Kleinman JE Lipska BK. Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain. Mol. Psychiatry, 2013.
  3. Ye T, Lipska BK, Tao R, Hyde TM, Wang L, Li C, Choi KH, Straub RE, Kleinman JE, Weinberger DR. Analysis of CNVs in Brain DNA from Patients with Schizophrenia and Other Psychiatric Disorders. Biol Psychiatry, 72(8):651-4, 2012.
  4. Numata S, Ye T, Hyde TM, Guitart-Navarro X, Tao R, Wininger M, Colantuoni C, Wienberger DR, Kleinman JE, Lipska BK. DNA methylation signatures in development and aging of the human prefrontal cortex. AJHG, 90:260-272, 2012.
  5. Lipska BK, Colantuoni C, Ye T, Hyde TM, Tao R, Leek JT, Colantuoni EA, Elkahloun AG, Herman MM, Daniel R. Weinberger1, Kleinman JE. Temporal Dynamics and Genetic Control of the Human Neocortical Transcriptome across the Lifespan. Nature, 478:519-524, 2011.
  6. Newburn EN, Morita Y, Hyde TM, Weinberger DR, Kleinman JE, Lipska BK. Interactions of Human Truncated DISC1 Proteins: Implications for Schizophrenia. Transl Psychiatry, 1:e30. doi: 10.1038/tp.2011.31.
  7. Hyde TM, Lipska BK, Ali T, Mathew SV, Law AJ, Metitiri O, Straub RE, Ye T, Herman MM, Bigelow LB, Weinberger DR, Kleinman JE. Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. J Neurosci, 2011, 31(30):11088-95.
  8. Lipska BK, Nakata K, Hyde TM, Ye T, Newburn EN, Morita Y, Vakkalanka R, Barenboim M, Sei Y, Weinberger DR, Kleinman JE. DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc.Natl Acad Sci U S A. 2009, 106(37):15873-8.
  9. Tseng KY, Chambers RA, Lipska BK. The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia. Behav Brain Res. 2009, 204(2):295-305.
  10. Sartorius LH, Weinberger DR, Hyde TM, Harrison PJ, Kleinman JE, Lipska BK. Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP. Neuropsychoparm. 33:2626-2634, 2008.
  11. Kunii Y, Hyde TM, Ye T, Li C, Kolachana BK, Dickinson D, Weinberger DR, Kleinman JE, Lipska BK. Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder, and genetic associations with t-DARPP-32 expression. Mol Psychiatry, 2012. In press.
  12. Ye T, Lipska BK, Tao R, Hyde TM, Wang L, Li C, Choi KH, Straub RE, Kleinman JE, Weinberger DR. Analysis of CNVs in Brain DNA from Patients with Schizophrenia and Other Psychiatric Disorders. Biol Psychiatry, 2012. In press.
  13. Numata S, Ye T, Hyde TM, Guitart-Navarro X, Tao R, Wininger M, Colantuoni C, Wienberger DR, Kleinman JE, Lipska BK. DNA methylation signatures in development and aging of the human prefrontal cortex. AJHG, 90:260-272, 2012.
  14. Lipska BK, Colantuoni C, Ye T, Hyde TM, Tao R, Leek JT, Colantuoni EA, Elkahloun AG, Herman MM, Daniel R. Weinberger1, Kleinman JE. Temporal Dynamics and Genetic Control of the Human Neocortical Transcriptome across the Lifespan. Nature, 478:519-524, 2011.
  15. Newburn EN, Morita Y, Hyde TM, Weinberger DR, Kleinman JE, Lipska BK. Interactions of Human Truncated DISC1 Proteins: Implications for Schizophrenia. Transl Psychiatry, 1:e30. doi: 10.1038/tp.2011.31.
  16. Hyde TM, Lipska BK, Ali T, Mathew SV, Law AJ, Metitiri O, Straub RE, Ye T, Herman MM, Bigelow LB, Weinberger DR, Kleinman JE. Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. J Neurosci, 2011, 31(30):11088-95.
  17. Lipska BK, Nakata K, Hyde TM, Ye T, Newburn EN, Morita Y, Vakkalanka R, Barenboim M, Sei Y, Weinberger DR, Kleinman JE. DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc.Natl Acad Sci U S A. 2009, 106(37):15873-8.
  18. Tseng KY, Chambers RA, Lipska BK. The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia. Behav Brain Res. 2009, 204(2):295-305.
  19. Sartorius LH, Weinberger DR, Hyde TM, Harrison PJ, Kleinman JE, Lipska BK. Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP. Neuropsychoparm. 33:2626-2634, 2008.