Skip to content

Multimedia About Imaging

More

Genes Impact Suspect Cortex Areas More as Youth Mature

Frame from the video.

Thickening of cortex areas implicated in mental illness shows increasing genetic influence as the brain develops in childhood and adolescence, NIMH researchers have found. These areas also happen to be the latest to evolve and the last to mature. The peak of genetic influence in these areas coincides with the typical age-of-onset of most mental disorders in late adolescence/early adulthood. The new findings may provide insight into the workings of gene-by-environment-by age interactions in the disorders, says Jay Giedd, M.D., of the NIMH Child Psychiatry Branch.

See: Genes Impact Suspect Cortex Areas More as Youth Mature

Credits:
Jay Giedd, M.D., Eric Schmitt, Ph.D., NIMH - MRI movies
Cristophe Lenglet, Ph.D., U. Minnesota -- DSI brain image
Van Wedeen, M.D., Harvard/MGH - DSI Animation
Brain & Behavior Research Foundation - video clip 
UCLA Laboratory of Neuro Imaging -- DSI animation from "Navigating the Connectome"

WatchRead Transcript

Channel Makover Switches Off Neurons in a Flash

Frame from the video.

Scientists have bioengineered an enhancement to a cutting edge technology that provides instant control over brain circuit activity with a flash of light. The research adds the same level of control over switching neurons off that, until now, had been limited to switching them on. What had been working through a weak pump now works through a highly responsive channel -- like going from a squirt to a gushing hose. Project officer Michelle Freund, Ph.D., of the NIMH Office of Technology Development and Coordination, explains the significance of the new findings.

See: Channel Makeover Bioengineered to Switch Off Neurons

Credits:
Karl Deisseroth, M.D. Ph.D, Stanford University
Andre Berndt, Ph.D., Stanford University
Soo Yeun Lee, Ph.D., Stanford University
Charu Ramakrishnan, Stanford University - channels image
Michelle Freund, Ph.D., NIMH

Method of the Year 2010: Optogenetics-NatureVideo  - animation
Optogenetics, Karl Deisseroth, Marina Coral, Nature Methods, 12/20/2010 - graphic

Richard Coppola, Sc.D., NIMH - MEG movie
Cristophe Lenglet, Ph.D., U. Minnesota - brain image

WatchRead Transcript

Brain’s Wiring Revealed in HD

Frame from the video.

New brain wiring images reveal a pervasive 3D grid structure with no diagonals, say scientists funded by the National Institutes of Health.

WatchRead Transcript

Development of the Young Brain

Frame from the video.

For more than twenty years, National Institute of Mental Health neuroscientist Dr. Jay Giedd has studied the development of the adolescent brain. Decades of imaging work have led to remarkable insight and a more than a few surprises.

WatchRead Transcript