- BRAIN Initiative as Moonshot
- “This was a very rigorous and tough competition”
NIH director Francis Collins, M.D., noted that slightly less than 10 percent of the applications were ultimately funded in the first wave of grants awarded by the NIH under the BRAIN Initiative. He spoke at a press conference announcing the awards, September 30, 2014.
- Not the “Usual Suspects”
NIMH director Thomas Insel, M.D., explained that NIH succeeded in recruiting researchers from outside neuroscience in the first wave of grants awarded by the NIH under the BRAIN Initiative. He spoke at a press conference announcing the awards, September 30, 2014.
- “A new era of exploration...”
Rockefeller University neuroscientist Cori Bargmann, Ph.D., discussed the promise of the BRAIN Initiative at a press conference announcing the first wave of awards, September 30, 2014.
- Follow That Cell
- Unearthing Secrets of New Neurons
Heather Frank, then a senior majoring in neuroscience at Colgate University, explains studies on neurogenesis that she worked on during an internship in the NIMH Unit on Neuroplasticity.
- Genes Impact Suspect Cortex Areas More as Youth Mature
Thickening of cortex areas implicated in mental illness shows increasing genetic influence as the brain develops in childhood and adolescence, NIMH researchers have found. These areas also happen to be the latest to evolve and the last to mature. The peak of genetic influence in these areas coincides with the typical age-of-onset of most mental disorders in late adolescence/early adulthood. The new findings may provide insight into the workings of gene-by-environment-by age interactions in the disorders, says Jay Giedd, M.D., of the NIMH Child Psychiatry Branch.
Jay Giedd, M.D., Eric Schmitt, Ph.D., NIMH - MRI movies
Cristophe Lenglet, Ph.D., U. Minnesota -- DSI brain image
Van Wedeen, M.D., Harvard/MGH - DSI Animation
Brain & Behavior Research Foundation - video clip
UCLA Laboratory of Neuro Imaging -- DSI animation from "Navigating the Connectome"
- Channel Makover Switches Off Neurons in a Flash
Scientists have bioengineered an enhancement to a cutting edge technology that provides instant control over brain circuit activity with a flash of light. The research adds the same level of control over switching neurons off that, until now, had been limited to switching them on. What had been working through a weak pump now works through a highly responsive channel -- like going from a squirt to a gushing hose. Project officer Michelle Freund, Ph.D., of the NIMH Office of Technology Development and Coordination, explains the significance of the new findings.
Karl Deisseroth, M.D. Ph.D, Stanford University
Andre Berndt, Ph.D., Stanford University
Soo Yeun Lee, Ph.D., Stanford University
Charu Ramakrishnan, Stanford University - channels image
Michelle Freund, Ph.D., NIMH
Method of the Year 2010: Optogenetics-NatureVideo - animation
Optogenetics, Karl Deisseroth, Marina Coral, Nature Methods, 12/20/2010 - graphic
Richard Coppola, Sc.D., NIMH - MEG movie
Cristophe Lenglet, Ph.D., U. Minnesota - brain image
- NIMH Outreach Partnership Program
The Outreach Partnership Program of the National Institute of Mental Health (NIMH) works to increase the public's access to science-based information through partnerships with national and state nonprofit organizations. With an emphasis on reaching underserved populations and promoting participation in research, the partnerships also help the NIMH understand concerns of those intended to benefit from the research the Institute supports.
- Patches of Disorganization in the Neocortex of Children with Autism
This video has no audio. The architecture of the autistic brain is speckled with patches of abnormal neurons, according to research partially funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health. Published in the New England Journal of Medicine on March 27, 2014, this study suggests that brain irregularities in children with autism can be traced back to prenatal development.
Source: Rich Stoner, Ph.D., University of California, San Diego