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Team-based Treatment for First Episode Psychosis Found to be High Value

Press Release

Recovery After an Initial Schizophrenia Episode

Coordinated Specialty Care for First Episode Psychosis is Cost Effective

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Genome-Wide Study Yields Markers of Lithium Response

Science Update

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Genome-Wide Study Yields Markers of Lithium Response

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Schizophrenia’s strongest known genetic risk deconstructed

Press Release

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Versions of a gene linked to schizophrenia may trigger runaway pruning of the teenage brain’s still-maturing communications infrastructure.The gene switched on more in people with the suspect versions, who faced a higher risk of developing the disorder.

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Experimental Combination Surprises with Anti-HIV Effectiveness

Science Update

HIV-infected T-cells

A compound developed by NIH-supported scientists to protect the nervous system from HIV surprised researchers by augmenting the effectiveness of an investigational antiretroviral drug beyond anything expected.

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Circuit Tweak Boosts Social Memory in Mice

Science Update

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Researchers have boosted the staying power of a social memory at least 80-fold by stimulating a circuit they discovered in mouse brain.

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Biomarkers Outperform Symptoms in Parsing Psychosis Subgroups

Press Release

Biotypes MRI

Three biomarker-based categories, called “biotypes,” outperformed traditional diagnoses, such as schizophrenia and bipolar disorder with psychosis, in sorting psychosis cases into distinct subgroups on the basis of brain biology

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Biomarker for Brain Excitability May Help Track Medication Effect

Science Update

illustration of neurons firing in brain

NIMH scientists have recently discovered a link between order in the activity of neurons in the brain and excitability—how likely it is that individual neurons will “fire”— which may provide a means for monitoring treatment of conditions like epilepsy that would be less invasive and thus more versatile than current methods

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NIH-supported NeuroBioBank Joins Autism BrainNet in Brain Donation Initiative

Press Release

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Two of the world’s largest brain tissue banks unify efforts to collect and distribute a critical number of brain donations for important autism research.

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Combating Early Death in People with Serious Mental Illness

Science Update

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Recent articles in JAMA Psychiatry report and comment on the premature mortality seen among adults with schizophrenia; NIMH research is underway to reduce health risk factors in people with serious mental illness.

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Federal Agencies Partner to Promote Coordinated Services for Patients with First Episode Psychosis

Science Update

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On October 16, the Centers for Medicare and Medicaid Services announced support for a new treatment for first episode psychosis called coordinated specialty care (CSC). This decision means more clinics may be able to offer CSC and it may become more readily available.

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