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GTEx Findings Reveal New Insights into how DNA Differences Influence Gene Activity, Disease Susceptibility

Press Release

Genotype-Tissue Expression Project chart shows locations for liver, heart and brain tissue within the human body

Data resource begins to reveal how genetic variability influences key tissues in health and disease.

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The NIMH Research Domain Criteria

Science Update

NIMH Research Domain Criteria

NIMH’s Research Domain Criteria (RDoC) is a groundbreaking initiative designed to help bring precision medicine to mental illnesses.

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Souped-up Remote Control Switches Behaviors On-and-off in Mice

Press Release

illustration of the effect of DREADD (Designer Receptors Activated Exclusively by Designer Drugs) bidirectional remote control of a neuron in a mouse brain circuit

Neuroscientists have perfected a chemical-genetic remote control for brain circuitry and behavior.

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Brain Circuitry for Positive vs Negative Memories Discovered in Mice

Press Release

Neuronal projections encoding negative (red) and positive (green) associations

Neuroscientists have discovered brain circuitry for encoding positive and negative learned associations in mice.

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A New Look at Racial/Ethnic Differences in Mental Health Service Use Among Adults

Science Update

Cover of the new report: Racial/Ethnic Differences in Mental Health Service Use Among Adults

New report on mental health service use among racial/ethnic groups

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Dr. Insel Reflects on Autism Awareness Month

Science Update

Dr. Thomas Insel

Dr. Insel describes recent accomplishments related to autism spectrum disorder over the past year—from the reauthorization of the Interagency Autism Coordinating Committee to promising therapeutic results from clinical trials.

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New NIMH Strategic Plan Aims to Focus, Accelerate Mental Health Research

Press Release

NIMH Strategic Plan for Research

New NIMH Strategic Plan balances the need for long-term investments in basic research with urgent mental health needs.

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HIV Can Spread Early, Evolve in Patients’ Brains

Press Release

HIV infecting T-Cell

HIV can replicate independently and early in the illness process, genetically evolving differently than in the periphery.

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NIH Announces Follow that Cell Challenge Finalists

Press Release

SCAP Challenge graphic thumbnail

NIH has selected 5 prize winners and 11 finalists in Phase 1 of its Follow that Cell Challenge, which aims to develop new ways to predict the behavior and function of a single cell in complex tissue over time.

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Lisanby Chosen to Lead NIMH Division of Translational Research

Science Update

Dr. Sarah H. Lisanby, M.D.

Dr. Sarah Hollingsworth Lisanby, one of the leading researchers in the area of neuromodulatory interventions for treating major depression, will join NIMH as the director of the Division of Translational Research.

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