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Designer Agent Blocks Pain in Mice Without Morphine’s Side Effects

Science Update

Scientists have synthesized a molecule with a unique profile of highly specific pain-relieving properties and demonstrated its efficacy in mice.

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How “Quickly Forgotten” Early Life Experiences Mature the Brain

Science Update

Brain memory circuitry’s keen sensitivity to experience during an early critical period enables long-term memory ability to develop through practice.

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Schizophrenia, Autism Risk Gene Trajectories Point to Shared Causes

Science Update

Schizophrenia, autism risk gene trajectories point to shared causes

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NIMH Grantees Named Recipients of Prestigious Kavli Prize

Science Update

Three NIMH grantees have been named recipients of the 2016 Kavli Prize in Neuroscience.

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Tapping Crowd-Sourced Data Unearths a Trove of Depression Genes

Press Release

Scientists have discovered 15 genome sites – the first ever – linked to depression in people of European ancestry. But – in a twist – the researchers didn’t have to sequence anyone’s genes! Instead, they analyzed data already shared by people who had purchased their own genetic profiles via an online service and elected to participate in its research option.

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Coping With Familial Mental Illness in Stressful Times

Science Update

“An NIH/NIMH lifer” reveals how his Asian American family successfully coped with severe mental illness compounded by discrimination.

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Connectome Map More Than Doubles Human Cortex’s Known Regions

Press Release

Researchers have mapped 180 distinct areas on our brain’s cortex — more than twice the number previously known.

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Electroconvulsive Therapy Lifts Depression, Sustains Remission in Older Adults

Science Update

An individualized program of follow-up treatment with electroconvulsive therapy (ECT) combined with an antidepressant was effective in preventing relapse in patients 60 years and older who had had a successful initial course of treatment for severe depression.

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Webinar: Analyzing and Using RDoC Data in Your Research

Institute Update

The NIMH Research Domain Criteria (RDoC) Unit hosts a webinar featuring a conversation with three NIMH-funded researchers who have approached the issue of how to analyze and integrate data that illustrate RDoC principles.

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Game Corrects Children’s Misreading of Emotional Faces to Tame Irritability

Science Update

A computer game that changes a tendency to misread ambiguous faces as angry is showing promise as a potential treatment for irritability in children

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