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Computer-Based Treatment Eases Anxiety Symptoms in Children
Science Update • March 13, 2012
girl_uses_laptop.jpg

Results from a small clinical trial suggest that it might be possible, using computer-based training, to help children with anxiety shift their attention away from threat.

Linked Brain Centers Mature in Sync
Science Update • March 13, 2012
MRI image of brain

Brain imaging is providing a new picture of how functionally connected parts of the brain develop in sync.

NIH-funded Study Defines Treatment Window for HIV-positive Children Infected at Birth
Press Release • March 07, 2012
mother holds baby boy

HIV-positive children older than 1 year who were treated after showing moderate HIV-related symptoms did not experience greater cognitive or behavior problems compared to peers treated when signs of their infection were still mild, according to a study funded by the National Institutes of Health.

Gene Regulator in Brain’s Executive Hub Tracked Across Lifespan – NIH study
Press Release • February 02, 2012
PFC methylation

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select club of genes in which regulatory activity peaks during an environmentally-sensitive critical period in development.

Ethnic Disparities Persist in Depression Diagnosis and Treatment Among Older Americans
Science Update • January 26, 2012
older African American male looking out to sea

Older racial and ethnic minorities living in the community are less likely to be diagnosed with depression than their white counterparts, but are also less likely to get treated, according to a recent NIMH-funded analysis published online ahead of print December 15, 2011, in the American Journal of Public Health.

Atypical Antipsychotic More Effective than Older Drugs in Treating Childhood Mania, but Side Effects Can Be Serious
Science Update • January 11, 2012
young children feeling frustrated

The antipsychotic medication risperidone is more effective for initial treatment of mania in children diagnosed with bipolar disorder compared to other mood stabilizing medications, but it carries the potential for serious metabolic side effects, according to an NIMH-funded study published online ahead of print January 2, 2012, in the Archives of General Psychiatry.

Turning on Dormant Gene May Hold Key for Correcting a Neurodevelopmental Defect
Science Update • January 05, 2012
Angelman syndrome

Scientists working in cell culture and in mice have been able to correct the loss of gene activity underlying a rare but severe developmental disorder by turning on a gene that is normally silenced in brain cells.

NDAR Federation Creates Largest Source of Autism Research Data to Date
Press Release • December 12, 2011
NDAR thumbnail

A data partnership between the National Database for Autism Research (NDAR), and the Autism Genetic Resource Exchange (AGRE) positions NDAR as possibly the largest repository to date of genetic, phenotypic, clinical, and medical imaging data related to research on autism spectrum disorders (ASD).

Suspect Gene Variants Boost PTSD Risk after Mass Shooting
Science Update • December 01, 2011
SERT and PTSD symptoms

College students exposed to a mass shooting were 20-30 percent more likely to later develop post traumatic stress disorder (PTSD) symptoms if they harbored a risk version of a gene, NIMH-funded researchers have discovered.

HIV Variants in Spinal Fluid May Hold Clues in Development of HIV-related Dementia
Science Update • November 30, 2011
illustration of brain and spinal cord

NIMH-funded researchers found two variants of HIV in the cerebrospinal fluid (CSF) of infected study participants that were genetically distinct from the viral variants found in the participants’ blood. The study, published October 6, 2011, in the journal PLoS Pathogens, suggests these CSF variants may help to inform research on the development and treatment of cognitive problems related to HIV infection.

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