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Learning Disability Reversed in Mice
November 25, 2008 • Science Update
Just as traffic signals enable safe traversing of the roadways, so too does the brain’s machinery for learning and memory rely on its own stop-and-go signals. An NIMH grantee has traced a human learning disability to an imbalance in signals that increase and decrease neural activity – and demonstrated a way to correct it. The study in mice, published in the October 31, 2008 issue of the journal Cell, advances scientific understanding of how memory works.
NIMH, U.S. Army Sign MOA to Conduct Groundbreaking Suicide Research
November 12, 2008 • Science Update
NIMH and the U.S. Army have entered into a memorandum of agreement (MOA) to conduct research that will help the Army reduce the rate of suicides.
Genomic Dragnet Finds Clues to Likely Suspects in Alzheimer’s
November 6, 2008 • Science Update
In the first study of its kind, researchers have pinpointed four genes likely associated with risk for the most common, late-onset form of Alzheimer’s disease, including a very strong candidate on chromosome 14. NIMH grantee Rudolph Tanzi, Ph.D., of Massachusetts General Hospital and Harvard University, and colleagues report on their findings in the November issue of the American Journal of Human Genetics.
Cells May Provide Target for New Anxiety Medications
November 6, 2008 • Science Update
A specific population of brain cells could provide a target for developing new medications aimed at helping people learn to mute the fears underlying anxiety disorders, according to NIMH-supported scientists.
Anxious and Healthy Adolescents Respond Differently to an Anxiety-provoking Situation
November 5, 2008 • Science Update
Brain scans show heightened activity among anxious adolescents exposed to an anxiety-provoking situation when compared with normal controls.
Genes That Turn On Together Hold Secrets of Brain’s Molecular Instructions
November 5, 2008 • Science Update
For the first time, scientists have mapped groups of genes that turn on together in the human brain, revealing a kind of Rosetta Stone of its molecular organization. These never-before-seen patterns of co-expressed genes hold promise for implicating genetic mechanisms conferring risk for illness through “guilt by association,” say the researchers.
New Grant Aims to Reduce Rate of College Suicide by Helping Students Better Adjust
October 31, 2008 • Science Update
A new grant funded by NIMH will test an intervention designed to prevent or reduce suicide among college students.
Brain’s Response to Scary Faces Imaged Faster Than You Can Say “Boo!”
October 31, 2008 • Science Update
Scientists have captured the split-second workings of the brain’s fear circuitry in people viewing frightful faces.
Study Identifies Three Effective Treatments for Childhood Anxiety Disorders
October 30, 2008 • Press Release
Treatment that combines a certain type of psychotherapy with an antidepressant medication is most likely to help children with anxiety disorders, but each of the treatments alone is also effective.
Brain’s Wiring Stunted, Lopsided in Childhood Onset Schizophrenia
October 30, 2008 • Science Update
Growth of the brain’s long distance connections, called white matter, is stunted and lopsided in children who develop psychosis before puberty, NIMH researchers have discovered.
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