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NIMH Workshop on Child Maltreatment and Trauma: Integrating Biological, Cognitive, and Social Trajectories of Development » Agenda

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Meeting Agenda
Bethesda, Maryland

Time Event
August 4, 2010
8:00-8:30 Check-in and light refreshments
8:30-9:00 Welcome, Introductions, and Meeting Charge

Molly Oliveri, PhD, Director, Division of Developmental Translational Research, NIMH
Christopher Sarampote, PhD, Chief, Trauma Program

Session 1 — Current Challenges in Child Maltreatment Research
Facilitator: Julia Zehr, PhD
9:00-10:15 Honing in on indiscriminate friendliness

Megan Gunnar, PhD

Early adverse experiences: Parsing the effects of maltreatment, family violence, and other potentially traumatic events

Margaret Briggs-Gowan, PhD

What can we learn about early life abuse from animal models?

Regina Sullivan, PhD

The effects of early psychosocial deprivation on brain-behavioral development

Charles Nelson, PhD

The neurobiological development of maltreated children with and without PTSD

Michael DeBellis, MD

10:15-10:30 Break
10:30-11:45 Discussion
Discussant
Eve Spratt, MD
Questions for Discussion: What are the current challenges in conducting child maltreatment research and what is known about long-term outcomes for these children? How is maltreatment operationalized in both humans and animal models? Discussion topics may include efforts to characterize, classify and understand maltreatment in children (e.g., abuse, neglect, interpersonal violence exposure) and the utility, validity and limitations of current animal models for understanding the effects of maltreatment and dimensions or components of maltreatment.
11:45-1:00 Lunch Break
Session 2 — Genetics of Maltreatment and Mental Health Outcomes
Facilitator: Holly Garriock, PhD
1:00-1:30 Childhood maltreatment, HPA-stress axis genes, and their interaction mediate adult psychopathology

Kerry Ressler, MD, PhD

Gene x childhood maltreatment interactions: Prediction of adult HPA axis function

Audrey Tyrka, MD, PhD

1:30-2:15 Discussion
Discussant
Dante Ciccetti, PhD
Questions for Discussion: What is known about the influence of genetics and gene x environment interactions for children exposed to maltreatment? What questions are addressable at this point and what new areas are the most promising?
2:15-2:30 BREAK
Session 3 — Neurocircuitry, Cognition, and Behavioral Outcomes of Maltreatment
Facilitator: Alice Luo-Clayton, PhD
2:30-3:30 Time and context in learning and forgetting

Marie Monfils, PhD

Infant maltreatment in Rhesus Monkeys: Developmental effects on brain and behavior

Mar Sanchez, PhD

Brain structure and function in youth with PTSD symptoms

Victor Carrion, MD

Long-term neurobiological correlates of childhood abuse in an inner-city African American population

Tanja Jovanovic, PhD

2:15-2:30 Break
3:40-5:00 Discussion
Discussants
Martin Teicher, MD
Nim Tottenham, PhD
Questions for Discussion: What is the effect of child maltreatment on the neurodevelopment of brain circuits, particularly top-down/bottom-up connectivity? How do these dysregulated circuits relate to behavioral outcomes and susceptibility for later psychopathology? Does the type of maltreatment (e.g., physical abuse vs. neglect), and the age of the child influence its impact on brain function? How can we leverage the knowledge gained about the neurobiology of other mental health disorders and apply it to child maltreatment research?
August 5, 2010
8:00-8:30 Light refreshments
8:30- 9:00 Day 1 Recap

Nathan Fox, PhD

Session 4 — Integrating Science, Intervention/Prevention
Facilitator: Susan Borja, PhD
9:30-10:30 Are current treatment and prevention interventions for child maltreatment culturally and linguistically appropriate for children from diverse backgrounds? What we think we know and what we still need to know

Michael de Arellano, PhD

Child maltreatment research: Emerging scientific findings, systems issues, and the unspoken elephant in the room

Joan Kauffman, MD

Integrating developmental, social and neurobiological research to develop best practices for child maltreatment prevention and intervention

Bekh Bradley-Davino, PhD

10:30-10:45 Break
10:45-12:00 Discussion
Discussants:
Xavier Castellanos, MD
Mark Chaffin, PhD
Patrick Tolan, PhD
Questions for Discussion: What biologic data should be collected in maltreatment studies and what type of information would be most informative (e.g., genetic; regulatory systems; imaging)? What is realistic and feasible? Is the field to a point where interventions could/should have hypotheses related to the biologic data that are collected, or is the field still gathering information/examining associations?
12:00-12:30 Next Steps
12:30 Adjourn