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Antipsychotic Medications May Ease Some Alzheimer’s Symptoms, Not Others
June 23, 2008 • Science Update
Antipsychotic medications may lessen symptoms like hostility and aggression in patients with Alzheimer’s disease, but do not appear to lessen other symptoms or improve quality of life, according to a recent analysis of data from the NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness Alzheimer’s Disease (CATIE-AD) study. The analysis was published online ahead of print June 2, 2008, in the American Journal of Psychiatry.
New Grant Aims to Overcome Obesity in People with Serious Mental Illness
June 20, 2008 • Science Update
A new grant funded by NIMH will test the effectiveness of a promising intervention designed to help people with serious mental illness (SMI) who are overweight or obese lose weight and keep it off.
HIV-positive Survivors of Sexual Abuse Who Receive Coping Intervention Less Likely to Engage in Unprotected Sex
May 23, 2008 • Science Update
HIV-positive people who have experienced childhood sexual abuse are less likely to engage in risky sexual behavior if they receive a group intervention designed to help them cope with their traumatic history, according to an NIMH-funded study.
Medication-only Therapy and Combination Therapy Both Cost Effective for Treating Teens with Depression
May 12, 2008 • Science Update
Treating depressed teenagers with either the antidepressant fluoxetine (Prozac) or a combination of fluoxetine and psychotherapy can be cost effective, according to a recent economic analysis.
Study launched to test possible preventive treatment for schizophrenia in high risk youth
May 1, 2008 • Science Update
NIMH recently awarded a grant to study whether an intensive, computerized training program can help prevent youth at high risk for developing schizophrenia from having a first psychotic episode and improve adaptive functioning.
Maintenance Treatment Crucial for Teens’ Recovery from Depression
April 8, 2008 • Science Update
Long-term maintenance treatment is likely to sustain improvement and prevent recurrence among adolescents with major depression, according to an NIMH-funded study.
Teens with Treatment-resistant Depression More Likely to Get Better with Switch to Combination Therapy
February 26, 2008 • Press Release
Teens with difficult-to-treat depression who do not respond to a first antidepressant medication are more likely to get well if they switch to another antidepressant medication and add psychotherapy rather than just switching to another antidepressant.
Group Therapy Program Offers Meaningful Gains for People with Borderline Personality Disorder
February 26, 2008 • Science Update
A 20-week group therapy program focusing on cognitive behavioral and skills training, when used in conjunction with usual care, helped reduce symptoms of borderline personality disorder and improve overall functioning, reported NIMH-funded researchers. Their findings were published online February 15, 2008 in the American Journal of Psychiatry.
Co-occurring Anxiety Complicates Treatment Response for Those with Major Depression
February 25, 2008 • Science Update
People with major depression accompanied by high levels of anxiety are significantly less likely to benefit from antidepressant medication than those without anxiety, according to a study based on data from the NIMH-funded Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study.
Genetic Variation May Influence Response to Depression Treatment
February 20, 2008 • Science Update
Variations in a gene known as TREK1 may explain some forms of treatment-resistant major depression, according to a new study analyzing genetic data.
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