NIMH Pages about Basic Research

Publications about Basic Research

Brain Development During Childhood and Adolescence (Fact Sheet)
A brain set in an outline of a woman’s profile. A fact sheet that describes the past, present and future of research on brain development.
Neuroimaging and Mental Illness: A Window Into the Brain
Neuroimaging FAQ Researchers use brain scans to study brain development in healthy people and people with illnesses. This publication answers frequently asked questions about what brain scans can and cannot do related to diagnosing mental illnesses.
A Participant's Guide to Mental Health Clinical Research
Participants Guide This brochure, prepared by the National Institute of Mental Health (NIMH), provides answers to common questions about volunteering for mental health clinical research.
Looking at My Genes: What Can They Tell Me?
A fact sheet containing frequently asked questions about genome scans and genetic testing.

Science News about Basic Research

Awake Mental Replay of Past Experiences Critical for Learning
Press Release • May 03, 2012
Awake Mental Replay Awake mental replay of past experiences is essential for making informed choices, suggests a study in rats. Without it, the animals’ memory-based decision-making faltered, say scientists funded by the National Institutes of Health.
Linked Brain Centers Mature in Sync
Science Update • March 13, 2012
MRI image of brain Brain imaging is providing a new picture of how functionally connected parts of the brain develop in sync.
Turning on Dormant Gene May Hold Key for Correcting a Neurodevelopmental Defect
Science Update • January 05, 2012
Angelman syndrome Scientists working in cell culture and in mice have been able to correct the loss of gene activity underlying a rare but severe developmental disorder by turning on a gene that is normally silenced in brain cells.
Biology, Not Just Society, May Increase Risk of Binge Eating During Puberty
Science Update • August 22, 2011
Lab rat sniffing cake frosting Biological changes associated with puberty may influence the development of binge eating and related eating disorders, according to a recent study on female rats conducted by NIMH-funded researchers.
New Neurons in Adult Brain Buffer Stress
Science Update • August 16, 2011
Photo of a mouse. New neurons growing in the adult brain help buffer the effects of stress, according to a new study in mice.

Posts about Basic Research

Time Matters – Why We Care So Much About Data Sharing

By Thomas Insel on May 21, 2012

Dr. Insel discusses the dynamics of data sharing in research.

Research Domain Criteria -- RDoC

By Thomas Insel on March 06, 2012

The RDoC project is an experimental approach to classification of mental disorders that will serve as a framework for ongoing research.

An Emerging Era of Big Data

By Thomas Insel on February 15, 2012

Dr. Insel discusses the emergence of “big data” and how open sharing of data could impact mental health research.

The Long Paths to Breakthroughs

By Thomas Insel on February 07, 2012

Dr. Insel talks about how basic research can lead to potential treatments.

Balancing Immediate Needs with Future Innovation

By Thomas Insel on January 26, 2012

Dr. Insel responds to discussion from the National Advisory Mental Health Council concerning the need to balance research funding for basic science and mental health services.


Meeting Summaries about Basic Research

Alliance for Research Progress — February 10, 2012 Meeting
February 10, 2012
Rockville, Maryland

Summary for the February 2012 meeting of the Alliance for Research Progress.
Alliance for Research Progress — July 29, 2011 Meeting
July 29, 2011
Bethesda, Maryland

Summary for the July 2011 meeting of the Alliance for Research Progress.
Navigating Your Way through a Successful Research Career: An NIMH Workshop for Early Stage Investigators
July 05, 2011 – July 06, 2011
Rockville, Maryland

On July 5-6, 2011, the Office for Research on Disparities and Global Mental Health (ORDGMH), in the Office of the Director of NIMH, sponsored a workshop for early stage investigators currently supported by Diversity and Re-entry Supplements, to provide the investigators with the tools necessary to continue along the path of competitive research support and the transition to independence. The workshop aimed to instill the importance of producing innovative research within the overall mission of the NIMH in these promising early career researchers. Content of the workshop emphasized issues relating to grantsmanship and strategies for successfully navigating obstacles and developing potential solutions on the journey to a successful research career.
Alliance for Research Progress — February 18, 2011 Meeting
February 18, 2011
Bethesda, Maryland

Summary for the February 2011 meeting of the Alliance for Research Progress.
The Maturation of Functional Brain Networks: Insight into the Origins and Course of Mental Disorders
January 27, 2011 – January 28, 2011
Washington, D.C.

Neural networks are a fundamental property of normal brain function, and dysregulated brain activity has been implicated in a wide array of mental disorders. In January 2011, NIMH convened a multi-disciplinary workshop of experts to discuss the opportunities and challenges of studying the maturation of neural networks in healthy and clinical populations. The workshop focused on non-invasive research tools, structure-function relationships, typical and atypical development, personalized biomarkers, and developmental connectivity maps.

Director’s Updates about Basic Research

NIMH Grantees Elected to Membership in National Academy of Sciences

May 17, 2012

On May 1, 2012, six NIMH grantees were among the 84 new members elected to the National Academy of Sciences, a private, non-profit organization of scientists and engineers dedicated to advancing science and promoting its uses for the greater good.

NIMH Grantees Elected to Membership in National Academy of Sciences

November 23, 2011

On May 3, 2011, nine NIMH grantees were among the 72 new members elected to the National Academy of Sciences, a private, non-profit organization of scientists and engineers dedicated to advancing science and promoting its uses for the greater good. The Academy also acts as an official advisor to the federal government on issues related to science and technology.

NIMH Grantees Elected to Membership in National Academy of Sciences

May 10, 2010

On April 27, 2010, three NIMH grantees were among the 72 new members elected to the National Academy of Sciences, a private, non-governmental organization of scientists and engineers dedicated to advancing science and promoting its uses for the greater good. The Academy also acts as an official advisor to the federal government on issues related to science and technology.

Linda Brady of NIMH Receives New Roadmap Compass Award

November 18, 2008

NIH Director Elias Zerhouni, MD, presented the first individual Roadmap Compass Award on October 24, 2008 to Linda Brady, Ph.D., director of the Division of Neuroscience and Basic Behavioral Science at NIMH, for her leadership and coordination of the Molecular Libraries Working Group.

National Advisory Mental Health Council Workgroup Issues Nine Recommendations to Strengthen Research Training

November 10, 2008

A workgroup of the National Advisory Mental Health Council (NAMHC) makes nine specific recommendations to strengthen the institute’s program in research training in a new report entitled “Investing in the Future” released on November 1, 2008.