Network Solutions
By Thomas Insel on February 05, 2013
Dr. Insel talks about how NIMH’s RAISE study is exploring an integrated, multi-component approach to health care for schizophrenia.
Topic Page: Clinical Research and Trials
NIMH Pages About Clinical Research and Trials
Overview of Clinical Research and Trials…
Publications About Clinical Research and Trials
- Neuroimaging and Mental Illness: A Window Into the Brain
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Researchers use brain scans to study brain development in healthy people and people with illnesses. This publication answers frequently asked questions about what brain scans can and cannot do related to diagnosing mental illnesses. - A Participant's Guide to Mental Health Clinical Research
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This brochure, prepared by the National Institute of Mental Health (NIMH), provides answers to common questions about volunteering for mental health clinical research. En Español
Science News About Clinical Research and Trials
- Community-based Treatments Offset Depression Disparities
- Science Update
Improving care for depression in low-income communities -- places where such help is frequently unavailable or hard to find -- provides greater benefits to those in need when community groups such as churches and even barber shops help lead the planning process, according to a new study.
- NIH Funds Industry Collaborations to Identify New Uses for Existing Compounds
- Press Release
NIH Funds Industry Collaborations to Identify New Uses for Existing Compounds
- Ketamine Cousin Rapidly Lifts Depression Without Side Effects
- Science Update
NMDA or glutamate receptor modulators as antidepressants have come of age. Human clinical studies demonstrated that ketamine can ward off depressive symptoms within 2 hours of administration and last for several days. Yet serious side effects are attached to this drug, including excessive sleepiness, hallucinations, and substance abuse behavior.
- NIH Study Shows People with Serious Mental Illnesses Can Lose Weight
- Press Release
Losing weight is challenging for everyone. It can be particularly difficult for someone with a serious mental illness. An NIMH-funded clinical study proves that a modified diet and exercise program can work for people with serious mental illnesses. Participants lost 7 pounds more than controls—and continued to lose weight.
- NIH-funded Study Finds Community-based Efforts Increase HIV Testing, Prompt Behavior Change
- Press Release
An international study supported by NIMH reported today that community efforts, in comparison to standard clinical testing and counseling, yielded greater testing and lower HIV incidence in high-risk individuals.
Posts About Clinical Research and Trials
From Practice to Research
By Thomas Insel on November 15, 2012
Dr. Insel introduces an innovative approach that one group is taking to speed up the dissemination of research results into clinical practice.
A Promising Behavioral Treatment for Tourette Syndrome
By Thomas Insel on August 06, 2012
Dr. Insel describes a new behavioral treatment for a neurologically based disorder that has traditionally been difficult to treat.
Experimental Medicine
By Thomas Insel on June 12, 2012
Dr. Insel discusses the crisis of medication development for mental disorders.
Citizen Science
By Thomas Insel on April 26, 2012
Presentations at a recent meeting in San Diego showed how new technologies are being used to change the culture of science, empowering patients, and fueling innovative research approaches.
Meeting Summaries About Clinical Research and Trials
- Alliance for Research Progress — February 8, 2013 Meeting
- February 08, 2013
Rockville, Maryland
Summary for the February 2013 meeting of the Alliance for Research Progress. - Alliance for Research Progress — July 13, 2012 Meeting
- July 13, 2012
Washington, DC
Summary for the July 2012 meeting of the Alliance for Research Progress. - Using Stem Cells for Biological and Therapeutics Discovery in Mental Illness
- April 24, 2012 – April 25, 2012
Bethesda, Maryland
On April 24-25, 2012, scientists from academia, government and the private sector met to discuss advances and challenges in using patient-derived reprogrammed cells, such as induced pluripotent stem cells (iPSCs) and induced neuronal cells (iNCs), to identify molecular, cellular, and developmental alterations relevant to mental illnesses and possible utility in diagnostics and drug development. - Alliance for Research Progress — February 10, 2012 Meeting
- February 10, 2012
Rockville, Maryland
Summary for the February 2012 meeting of the Alliance for Research Progress. - Alliance for Research Progress — July 29, 2011 Meeting
- July 29, 2011
Bethesda, Maryland
Summary for the July 2011 meeting of the Alliance for Research Progress.
Director’s Updates About Clinical Research and Trials
- NIMH Clinical Director Receives Prestigious Leadership Award
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November 15, 2012
NIMH clinical director Dr. Maryland Pao has been named the 2012 recipient of the Simon Wile Leadership in Consultation Award by the American Academy of Child & Adolescent Psychiatry (AACAP).
- New and Existing Clinical Datasets Available to Qualified Researchers
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June 15, 2012
Are you a researcher interested in studying datasets from NIMH clinical trials? If so, several datasets are available to those who are qualified.
- NIMH Perspective on Diagnosing and Treating Bipolar Disorder in Children
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September 03, 2007
A recently published research paper (September 2007, Archives of General Psychiatry) reported a 40-fold increase in the rate of diagnosing bipolar disorder in youth over the past decade.
- NIMH Perspective on Antipsychotic Reimbursement: Using Results from the CATIE Cost Effectiveness Study
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December 01, 2006
The recent publication (December 1, 2006, American Journal of Psychiatry) of the cost-effectiveness results from the National Institute of Mental Health (NIMH)-funded Clinical Antipsychotic Trials in Intervention Effectiveness (CATIE) has raised questions among advocates, families, and clinicians about reimbursement policies for antipsychotic medications.
- NIMH Perspective on Treating Alzheimer’s Patients with Antipsychotic Medications
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October 12, 2006
The recent publication of phase 1 results from the NIMH-funded Clinical Antipsychotic Trials in Intervention Effectiveness for Alzheimer's disease (CATIE-AD) in the New England Journal of Medicine provides new information about the use of several "atypical" antipsychotic medications for the treatment of psychotic symptoms in patients with Alzheimer's disease.