Topic Page: Depression

NIMH Pages About Depression

Overview of Depression…


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Publications About Depression

Depression and Parkinson's Disease
Cover image for the Depression and Parkinson's Disease publication.This brochure describes the signs and symptoms of depression and how it is linked to other illnesses, including Parkinson's disease. En Español
Depression and Stroke
Cover image for the Depression and Stroke publication.This brochure describes the signs and symptoms of depression and how it is linked to other illnesses, including stroke. En Español
Depression and Osteoporosis
Cover image for the Depression and Osteoporosis publication.This brochure describes the signs and symptoms of depression and how it is linked to other illnesses, including osteoporosis. En Español
Depression and HIV/AIDS
Cover image for the Depression and HIV/AIDS publication.This brochure describes the signs and symptoms of depression and how it is linked to other illnesses, including HIV/AIDS. En Español
Depression and Chronic Pain
Cover image for the Depression and Chronic Pain publication.This brochure describes the signs and symptoms of depression and how it is linked to other illnesses, including chronic pain. En Español

Science News About Depression

Scan Predicts Whether Therapy or Meds Will Best Lift Depression
Press Release •
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Pre-treatment scans of brain activity predicted whether depressed patients would best achieve remission with an antidepressant medication or psychotherapy, in a study that may help mental health treatment decision-making move beyond trial-and-error. The study sought to identify a biomarker that could predict which type of treatment a patient would benefit from based on the state of his or her brain.

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Bullying Exerts Psychiatric Effects Into Adulthood
Science Update •
Bullying Exerts Psychiatric Effects Into Adulthood

Once considered a childhood rite of passage, bullying lingers well into adulthood. Bullies and victims alike are at risk for psychiatric problems such as anxiety, depression, substance abuse, and suicide when they become adults, reported a study partially funded by the National Institute of Mental Health (NIMH) that was published in the April issue of JAMA Psychiatry.

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Ketamine Cousin Rapidly Lifts Depression Without Side Effects
Science Update •
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NMDA or glutamate receptor modulators as antidepressants have come of age. Human clinical studies demonstrated that ketamine can ward off depressive symptoms within 2 hours of administration and last for several days. Yet serious side effects are attached to this drug, including excessive sleepiness, hallucinations, and substance abuse behavior.

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NIH Study Shows People with Serious Mental Illnesses Can Lose Weight
Press Release •
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Losing weight is challenging for everyone. It can be particularly difficult for someone with a serious mental illness. An NIMH-funded clinical study proves that a modified diet and exercise program can work for people with serious mental illnesses. Participants lost 7 pounds more than controls—and continued to lose weight.

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Five Major Mental Disorders Share Genetic Roots
Science Update •
Dr. Bruce Cuthbert, Ph.D.

Five major mental disorders share some of the same genetic risk factors, the largest genome-wide study of its kind has found.

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Posts About Depression

Summer Science

By Thomas Insel on August 24, 2012

Numerous provocative advances in neuroscience were reported during the summer of 2012.

Antidepressants: A complicated picture

By Thomas Insel on December 06, 2011

Dr. Insel discusses the complicated nature of research on the efficacy antidepressants.

How Does Memory Work? The Plot Thickens

By Thomas Insel on February 10, 2011

Rapid progress in understanding how memory works – from the molecular to the behavioral level – holds promise for improved treatment of memory components of mental disorders.

NIMH’s Top 10 Research Events and Advances of 2010

By Thomas Insel on December 23, 2010

10 breakthroughs and events of 2010 which are changing the way we approach mental disorders.

Spotlight on Postpartum Depression

By Thomas Insel on October 28, 2010

Dr. Insel summarizes NIMH’s research efforts to better understand and treat postpartum depression.


Meeting Summaries About Depression

Closing the Gaps: Reducing Disparities in Mental Health Treatment through Engagement
September 12, 2011 – September 13, 2011
Bethesda, Maryland

In September 2011, the Office for Research on Disparities and Global Mental Health (ORDGMH) in the Office of the Director and the Division of Services and Intervention Research (DSIR) at NIMH convened a workshop, “Closing the Gaps: Reducing Disparities in Mental Health Treatment through Engagement.” This workshop brought together thought leaders from a range of fields—epidemiology, psychology, psychiatry, social work, and community-based services and intervention research—and representatives of key federal agencies to discuss the role of engagement in reducing mental health treatment disparities.
Fresh Perspectives in Perinatal Depression Research: Psychosocial Interventions and Mental Health Services
October 05, 2010 – October 06, 2010
Rockville, Maryland

On October 5-6, 2010, the NIMH Division of Services and Intervention Research (DSIR) convened a workshop to provide the growing number of early-stage perinatal depression psychosocial intervention and services investigators with the opportunity to discuss research strategies consistent with public health needs and NIMH priorities.
Perinatal Mood Disorders: Components of Care
May 07, 2009 – May 08, 2009
Bethesda, Maryland

A two-day meeting convened in May 2009 educated participants on essential components of care for women with perinatal mood disorders
Research Roundtable: Heterogeneity in Child and Adolescent Depression
February 18, 2008 – February 19, 2008
Washington, DC

The purpose of this workshop was to discuss empirical evidence for sources of heterogeneity in child and adolescent depression, evaluate the significance of known heterogeneity, and identify promising research directions in this area.
Benefits, Limitations, and Emerging Research Needs in Treating Youth with Depression
February 06, 2006 – February 07, 2006
Washington, DC

On February 6 and 7, 2006, experts in child and adolescent depression met in Washington, DC to review the state of the science of the treatment of youth depression and discuss approaches to further research.