NIMH Pages about Genetics

Publications about Genetics

Looking at My Genes: What Can They Tell Me?
A fact sheet containing frequently asked questions about genome scans and genetic testing.

Science News about Genetics

Spontaneous Gene Glitches Linked to Autism Risk with Older Dads
Press Release • April 04, 2012
Autism genetics A trio of new studies have found that sequence changes in parts of genes that code for proteins play a significant role in autism spectrum disorders (ASDs).
Friendly-to-a-Fault, Yet Tense: Personality Traits Traced in Brain
Press Release • March 19, 2012
Williams syndrome MRI NIH scientists have used three different types of brain imaging to pinpoint a circuit hub buried deep in the front center of the brain in people with Williams syndrome, a rare genetic disorder characterized by overly gregarious yet anxious behavior.
Gene Regulator in Brain’s Executive Hub Tracked Across Lifespan – NIH study
Press Release • February 02, 2012
PFC methylation For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select club of genes in which regulatory activity peaks during an environmentally-sensitive critical period in development.
Turning on Dormant Gene May Hold Key for Correcting a Neurodevelopmental Defect
Science Update • January 05, 2012
Angelman syndrome Scientists working in cell culture and in mice have been able to correct the loss of gene activity underlying a rare but severe developmental disorder by turning on a gene that is normally silenced in brain cells.
Suspect Gene Variants Boost PTSD Risk after Mass Shooting
Science Update • December 01, 2011
SERT and PTSD symptoms College students exposed to a mass shooting were 20-30 percent more likely to later develop post traumatic stress disorder (PTSD) symptoms if they harbored a risk version of a gene, NIMH-funded researchers have discovered.

Posts about Genetics

The New Genetics of Autism – Why Environment Matters

By Thomas Insel on April 04, 2012

Dr. Insel discusses how new research may help tie together seemingly disparate findings in genetic vs environmental risk factors in autism spectrum disorders.

NIMH’s Top 10 Research Advances of 2011

By Thomas Insel on December 23, 2011

Dr. Insel shares NIMH’s Top 10 Research Advances for 2011.

Neuroscience Advances Showcased in Washington

By Thomas Insel on November 18, 2011

Dr. Insel reflects on an exciting neuroscience conference where an increasing interest in neuropsychiatric disorders was evident.

A New Picture of Brain Development

By Thomas Insel on October 28, 2011

Two papers published this week in Nature provide the first maps of the molecular development of the human brain. Mapping brain development by changes in gene expression gives us a new level of precision and raises new possibilities for understanding the mechanisms of neurodevelopmental disorders.

Psychiatric Genetics: More Pieces of the Puzzle

By Thomas Insel on October 04, 2011

Results of the two largest studies of their kind, to date, have identified new common gene variants associated with schizophrenia and bipolar disorder. The results implicate specific pathways and hold promise for development of new treatments.