Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- A Magnetic Resonance Spectroscopic Examination of Children and Adolescents Taking Riluzole for Obsessive-Compulsive Disorder.
Evaluation study. Background: - Obsessive-compulsive disorder (OCD) is a common childhood disorder that often does not respond to standard treatments. Ages 7-17. Location in Bethesda, MD.
- Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder.
Interventional study. This study will examine the way cognitive behavioral therapy changes the structure of the brain in patients with obsessive-compulsive disorder and will thereby determine what makes cognitive behavioral therapy an effective treatment. Ages 6-18. Location in Los Angeles, CA.
- Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder.
Interventional study. This study will evaluate the safety and effectiveness of deep brain stimulation in treating people with severe and otherwise treatment-resistant obsessive-compulsive disorder. Ages 18-75. Locations in Gainesville, FL; Boston, MA; New York, NY; Cleveland, OH; Providence, RI.
- Comparing the Effectiveness of Two Family-Based Therapies in Treating Young Children With Obsessive-Compulsive Disorder.
Interventional study. This study will compare the effectiveness of family-based cognitive behavioral therapy to family-based relaxation therapy in treating young children with obsessive-compulsive disorder. Ages 5-8. Locations in Durham, NC; Philadelphia, PA; Providence, RI.
- Evaluating the Effects of Stress in Pregnancy.
Evaluation study. This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy. Ages 18-45. Location in Atlanta, GA.
- Pharmacogenomics of Antidepressant Response in Children and Adolescents.
Evaluation study. This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications. Ages 7-17. Location in Durham, NC.
- Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders.
Evaluation study. This study will look at similarities and differences in family processes and child temperament among children with and without symptoms of anxiety disorders. Ages 8-12. Location in Providence, RI.
- Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder.
Interventional study. This study will determine the effectiveness of adding motivational interviewing to cognitive behavioral therapy, consisting of exposure and ritual prevention, in improving treatment outcomes in people with obsessive-compulsive disorder. Ages 18-70. Location in New York, NY.
- Stepped Care for Treating Obsessive-Compulsive Disorder.
Interventional study. This study will determine the effectiveness and cost-effectiveness of a stepped-care treatment program for people with obsessive-compulsive disorder. Ages 18-69. Location in Hartford, CT.
- Treatment of Obsessive Compulsive Disorder in Children.
Interventional study. This study will determine whether cognitive behavioral therapy delivered by either psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor treatment in children with obsessive compulsive disorder. Ages 7-17. Locations in Durham, NC; Philadelphia, PA; Providence, RI.
Search ClinicalTrials.gov for other NIH studies on Obsessive-Compulsive Disorder(OCD).
Related Information
- Learn more about Obsessive-Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder, OCD, is an anxiety disorder and is characterized by recurrent, unwanted thoughts (obsessions) and/or repetitive behaviors (compulsions). Repetitive behaviors such as handwashing, counting, checking, or cleaning are often performed with the hope of preventing obsessive thoughts or making them go away. Performing these so-called “rituals,” however, provides only temporary relief, and not performing them markedly increases anxiety.
Clinical Research at NIMH
- For opportunities to participate in NIMH research on the NIH campus, visit the patient recruitment Website. Travel and lodging assistance available.
