Skip to content

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC:
Get the latest research information from NIH:

RDoC Changes to the Matrix Workgroup (CMAT)



The National Advisory Mental Health Council (NAMHC) Workgroup on Changes to the RDoC Matrix (CMAT) advises the council on revisions and modifications to the RDoC framework. This workgroup was approved by the NAMHC at the September 2016 meeting. The workgroup members will not be solely responsible for the substantive evaluation of proposed changes, but rather act as a coordinating committee whose members suggest and recruit subject-matter experts as needed. After receiving input from these outside experts, the workgroup compiles a report for submission to the Advisory Council for its approval. A primary function of this workgroup is to provide a consistent approach to the strength of evidence needed to recommend any particular change to the RDoC framework.

Workgroup Charge

Currently, the RDoC matrix consists of six domains of human behavior and functioning, associated constructs and sub-constructs, and elements in the cells of the matrix across the various units of analysis used to index them. The purpose of the CMAT workgroup is to evaluate the evidence for a modification of the matrix and recommend precisely how to include the information for that component. When evaluating the evidence for the addition of a new construct, the following three criteria (utilized in the original RDoC workshops) must be satisfied:

  • Is there evidence for the validity of the construct as a functional unit of behavior?
  • Is there evidence of a neural circuit or system that plays a primary role in implementing the construct’s function?
  • Is the construct relevant to understanding some aspect of psychopathology?

The workgroup may optimize these basic criteria for components by the addition of other conditions.