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News and Multimedia from 2014 Featuring DNBBS

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Largest Autism Gene Dragnet Fingers 33 Prime Suspects

Science Update

Many patients with psychosis develop health risks associated with premature death early in the course of their mental illness, researchers have found.

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NIH Announces First Wave of Funding for BRAIN Initiative Research

Science Update

Calling it “the beginning of an ambitious journey”, the National Institutes of Health announced its first wave of grants in support of the BRAIN Initiative.

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Video.
BRAIN Initiative as Moonshot

NIH director Francis Collins, M.D., discusses some of the 58 projects funded in the first wave of grants awarded by the NIH under the BRAIN Initiative. He spoke at a press conference announcing the awards, September 30, 2014.

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Magnetic Stimulation Boosts Human Memory, Network Connectivity

Science Update

Scientists have improved memory for associations between faces and words by electromagnetically stimulating neural connections in a brain network.

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Suspect Gene Corrupts Neural Connections

Press Release

Researchers have shown in patients’ cells how a rare mutation in a suspect gene disrupts the expression of dozens of other genes underlying neural connections.

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Follow that Cell

Press Release

The National Institutes of Health is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time.

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Schizophrenia’s Genetic “Skyline” Rising

Press Release

The largest genomic dragnet of any psychiatric disorder to date has unmasked 108 chromosomal sites harboring inherited variations in the genetic code linked to schizophrenia, 83 of which had not been previously reported.

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Common Gene Variants Account for Most Genetic Risk for Autism

Press Release

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

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Shining a Light on Memory

Press Release

Using a flash of light, scientists have inactivated and then reactivated a memory in genetically engineered rats. The findings – the first cause-and-effect evidence that strengthened connections between neurons are the stuff of memory – add to mounting evidence that the brain represents a memory by forming assemblies of neurons with strengthened connections.

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Jump-starting Natural Resilience Reverses Stress Susceptibility

Press Release

Scientists have traced vulnerability to depression-like behaviors to out-of-balance neuronal electrical activity and made mice resilient by reversing it.

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NIH-funded Brain Atlas Offers Clues to Psychiatric Disorders

Press Release

A brain blueprint maps where genes are tuned on and off during mid-pregnancy—when most brain disorders such as autism and schizophrenia occur.

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Brain Region Singled Out for Social Memory, Possible Therapeutic Target for Select Brain Disorders

Science Update

The hippocampus houses learning and memory—specifically the storage of knowledge of who, what, where, and when. Using a special transgenic mouse, researchers have now pinpointed a hippocampal region called CA2 that is important for social memory, the ability of animal to recognize another of the same species. Understanding this region could be useful in understanding and treating disorders characterized by altered social behaviors such as schizophrenia, bipolar disorder, and autism.

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