Recent News and Multimedia Featuring DNBBS
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- NIH Completes Atlas of Human DNA Differences that Influence Gene Expression
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• Science Update
NIH researchers have completed an atlas documenting how DNA influence human gene expression.
- Depression’s “Transcriptional Signatures” Differ in Men vs. Women
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• Science Update
Brain gene expression associated with depression differed markedly between men and women. Such divergent “transcriptional signatures” may signal divergent underlying illness processes requiring sex-specific treatments.
- Scientists Give Star Treatment to Lesser-Known Cells Crucial for Brain Development
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• Press Release
Star-shaped support brain cells, astrocytes, growing in 3-D “organoids” in a dish develop similarly as those in human brain tissue.
- Patient-Derived Support Cells Stunt Mouse Brain Development
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• Science Update
Support cells generated from patients with childhood onset schizophrenia stunted neural circuit development when grafted into developing mouse brains.
- NIH Names Winners of “Follow that Cell” Phase 2 Competition
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• Press Release
Two biological engineering researchers are winners in Phase 2 of NIH’s Follow that Cell Challenge. The winners will share $400,000 in prizes awarded for development of new tools and methods for predicting the behavior and function of a single cell in complex tissue over time – and how that reflects the health of the tissue.
- Brain Circuit Tweak Wins Her Affection (if she’s a vole)
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• Science Update
For the first time, neuroscientists have boosted a female rodent’s partnering with a male by stimulating connectivity of a brain reward circuit. Understanding the circuitry of such affiliative behaviors may lead to improved treatments for social impairment in severe mental disorders, such as autism spectrum disorder.
- Brain “Relay” Also Key to Holding Thoughts in Mind
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• Press Release
Long overlooked as a mere “relay,” an egg-like structure in the middle of the brain also turns out to play a pivotal role in tuning-up thinking circuity. A trio of studies in mice are revealing that the thalamus sustains the ability to distinguish categories and hold thoughts in mind. It might even become a target for interventions for psychiatric disorders marked by working memory problems, such as schizophrenia.
- Human Forebrain Circuits Under Construction – in a Dish
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• Press Release
Neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development.
- Human Forebrain Circuits Wiring-up - in a Dish
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Neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development.
- Sleep May Trim Neural Connections to Restore Learning Ability
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• Science Update
Sleep may be the price we pay for the ability to learn. It streamlines neural connections for optimal efficiency.
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