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Brain Circuit Tweak Wins Her Affection (if she’s a vole)

Science Update

For the first time, neuroscientists have boosted a female rodent’s partnering with a male by stimulating connectivity of a brain reward circuit. Understanding the circuitry of such affiliative behaviors may lead to improved treatments for social impairment in severe mental disorders, such as autism spectrum disorder.

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Brain “Relay” Also Key to Holding Thoughts in Mind

Press Release

Long overlooked as a mere “relay,” an egg-like structure in the middle of the brain also turns out to play a pivotal role in tuning-up thinking circuity. A trio of studies in mice are revealing that the thalamus sustains the ability to distinguish categories and hold thoughts in mind. It might even become a target for interventions for psychiatric disorders marked by working memory problems, such as schizophrenia.

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Human Forebrain Circuits Under Construction – in a Dish

Press Release

Neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development.

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Human Forebrain Circuits Wiring-up - in a Dish

Neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development.

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Sleep May Trim Neural Connections to Restore Learning Ability

Science Update

Sleep may be the price we pay for the ability to learn. It streamlines neural connections for optimal efficiency.

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Revealed: LSD Docked in its Human Brain Target

Science Update

Scientists have discovered the molecular structure of LSD in its human brain receptor.

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NIMH Training Grant Recipient Wins Research Prize

Science Update

NIMH training grant recipient Neir Eshel was named the 2016 Grand Prize winner of the Science & SciLifeLab Prize for Young Scientists for research related to the cellular basis of learning.

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Powered-Up Probe ID’s Schizophrenia Genes That Stunt Brain Development

Science Update

Scientists have pinpointed several schizophrenia-related gene variants that alter expression of other genes in illness-implicated circuitry of the human brain.

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Circuitry for Fearful Feelings, Behavior Untangled in Anxiety Disorders

Science Update

Untangling the brain circuitry of fearful feelings from that underlying defensive behaviors is key to improving treatments for anxiety disorders, argue two leading experts.

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Designer Agent Blocks Pain in Mice Without Morphine’s Side Effects

Science Update

Scientists have synthesized a molecule with a unique profile of highly specific pain-relieving properties and demonstrated its efficacy in mice.

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