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Learn about the progress NIMH has made toward Goal 3 of the NIMH Strategic Plan for Research: Strive for Prevention and Cures.

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  NIMH Addresses Critical Need for Rapid-Acting Interventions for Severe Suicide Risk

  NIMH is working to meet the urgent need for rapid-acting suicide prevention interventions by supporting research investigating the feasibility and safety of treatment protocols that have the potential to quickly reduce severe suicide risk in youth and adults.

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  Adaptive Screener May Help Identify Youth at Risk of Suicide

  In a study supported by NIMH, researchers have developed a computerized adaptive screener that can help identify youth at risk for attempting suicide.

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  Using Mobile Technology to Improve Care for Teens with Depression

  In a project funded by the NIMH Small Business Technology Transfer program, researchers are investigating whether mobile technology can be used to create a passive monitoring system that can predict teens’ depressive symptoms and improve the quality of their care.

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  Testing and Refining Biomarkers to Support Intervention Research for Children with Autism

  NIMH, along with other NIH Institutes, is supporting the ABC-CT project, a multisite study that aims to test and refine biomarkers that can be used as objective measures of social impairment for children with autism in clinical trials, leading to more predictive and personalized treatment.

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  Brief Suicide Prevention Interventions in Acute Care Settings May Reduce Subsequent Suicide Attempts

  A research project supported by NIMH analyzed multiple studies to determine the effectiveness of brief suicide prevention interventions in acute care settings.

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  Differences in Suicide Risk Among Subgroups of Sexual and Gender Minority College Students

  In an NIMH-supported study, researchers found that college students identifying as a sexual or gender minority had higher rates of suicidal risk factors than cisgender and heterosexual peers, and that there were significant differences in risk among sexual minority subgroups.

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  Supporting the Development of Early Autism Screening Tools

  NIMH, along with other NIH Institutes, is supporting the goal of identifying autism in the first year of life by funding projects that seek to seek to translate findings related to early-emerging signs of autism into practical ASD screening tools that can be implemented in the general population and community settings.

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  Fast-Fail Trial Shows New Approach to Identifying Brain Targets for Clinical Treatments

  An innovative NIMH-funded trial shows that a receptor involved in the brain’s reward system may be a viable target for treating anhedonia (or lack of pleasure), a key symptom of several mood and anxiety disorders.

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  Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults

  The use of right unilateral ultrabrief pulse (RUL-UB) electroconvulsive therapy (ECT) in combination with the antidepressant venlafaxine to treat depression in elderly patients is well tolerated and results in minimal neurocognitive side effects, according to a new NIH-funded study published in the American Journal of Geriatric Psychiatry.

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  Neural Signature Identifies People Likely to Respond to Antidepressant Medication

  NIH-funded research uses machine learning algorithm to predict individual response to a commonly-prescribed antidepressant.

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