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Ketamine Lifts Depression via a Byproduct of its Metabolism

Press Release

A chemical byproduct, or metabolite, created as the body breaks down likely holds the secret to its rapid antidepressant action .

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Secrets to Our Smarts Hidden in the Folds of Our Cortex

Science Update

The more folding in the thinking parts of our brain, the smarter we are – to a degree.

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Circuit Tweak Boosts Social Memory in Mice

Science Update

Researchers have boosted the staying power of a social memory at least 80-fold by stimulating a circuit they discovered in mouse brain.

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NIMH Twitter Chat on Clinical Research Participation

Live Chat

NIMH Twitter Chat on Men and Depression

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Rapid Agent Restores Pleasure-seeking Ahead of Other Antidepressant Action

Press Release

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior independent of – and ahead of – its other antidepressant effects.

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NIMH Twitter Chat on Depression and the Development of Novel Medications

Science Update

NIMH Twitter Chat on Depression and the Development of Novel Medications

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Unearthing Secrets of New Neurons

Video.

Unearthing Secrets of New Neurons

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NIMH Twitter Chat on Premenstrual Dysphoric Disorder

Science Update

NIMH Twitter Chat on Premenstrual Dysphoric Disorder

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Common Gene Variants Account for Most Genetic Risk for Autism

Press Release

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

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Genes Impact Suspect Cortex Areas More as Youth Mature

Science Update

Later evolving and maturing brain areas, which also are those most implicated in mental illness, showed gradually increasing heritability, peaking by late adolescence – the age-of-onset for most mental disorders. New findings hold promise for understanding how age plays an important role in gene-environment interactions that underlie the disorders.

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