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PMS: Studying the Possible Causes

Join a Research Study: Enrolling locally from the Washington, D.C. metro region

To find out if you qualify, email NIMH or call 1-301-496-9576 [TTY: 1-866-411-1010].

If you are a woman between 18 and 50 who experiences premenstrual syndrome (PMS), you may be eligible to help researchers investigate what causes it. This study explores possible causes of PMS by using a medication to stop the menstrual cycle temporarily. After the menstrual cycle is stopped, researchers will add back, in sequence, estrogen, and progesterone. The purpose of this study is to examine the influence of estrogen and progesterone on mood and behavior in women with PMS.