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Principal Investigator

Photo of Argyris Stringaris, MD, PhD, Chief of Mood Brain and Development Unit in the Emotion and Development Branch of NIMH IRP.

Argyris Stringaris, M.D., Ph.D., FRCPsych

Mood Brain & Development Unit (MBDU)


Argyris Stringaris, MD, PhD, FRCPsych researches and treats depression and related conditions in young people. He trained in Child & Adolescent Psychiatry at the Maudsley Hospital in London and received his PhD from the Institute of Psychiatry, King’s College London. He served as an Attending Physician (Consultant Psychiatrist) at the National and Specialist Mood Disorder Clinic at the Maudsley and was a Senior Lecturer at the Institute of Psychiatry. He held an advanced Wellcome Trust fellowship and his research was funded by the National Institute of Health Research and the UK Biomedical Centre. His work on mood disorders has been awarded the 2014 Klingenstein Foundation Prize by the American Academy of Child and Adolescent Psychiatry, and the 2010 Research Prize from the European Psychiatric Association (EPA). His most recent book (co-authored with Eric Taylor) was published by Oxford University Press and awarded a High Commendation by the British Medical Association (2016). In 2018, Dr Stringaris was awarded the National Institute of Mental Health Outstanding Mentor Award. Also, in 2018 Dr Stringaris was elected a Fellow of the Royal College of Psychiatrists as mark of distinction and recognition for his contributions to psychiatry.

Research Interests

Dr. Stringaris is interested in how mood is generated and maintained and seeks to use this knowledge in order to improve the treatment of young people with depression and related conditions. He uses neuroimaging, epidemiology and treatment studies (cognitive behavioral therapy and medication) to probe brain mechanisms involved in mood and emotion processing. He has a special interest in reward processing and how it relates to patient’s feelings and decision making. A central part of his work is to improve the way we measure mood using multimethod-multisource approaches.

Selected Publications

Is Reward Prediction Error encoding reliable during development?. Keren H, Chen G, Benson B, Ernst M, Leibenluft E, Fox N, Pine DS, Stringaris A. NeuroImage. (2018) (in press) PMID: 29777827.

Reward processing in depression: a conceptual and meta-analytic review across electrophysiological and fMRI studies. Keren H, O’Callaghan G, Vidal-Ribas P, Buzzell GA, Brotman M, Leibenluft E, Pan PM, Meffert L, Kaiser A, Wolke S, Pine D, Stringaris A. Am J Psychiatry . (2018) (in press) PMID: 29921146.

Ventral striatal connectivity as a predictor of adolescent depressive disorder in a longitudinal community-based sample. Pan P, Sato J, Salum G, Rohde, LA, Gadelha A, Zugman A, Mari J, Jackowski A, Picon F, Miguel EC, Pine DS, Leibenluft E, Bressan R, Stringaris A. Am J Psychiatry. (2017) 174, 1112-1119 PMID: 28946760.

The brain’s response to reward anticipation and depression in adolescence: dimensionality, specificity and longitudinal predictions in a community-based sample. Stringaris A, Vidal-Ribas Belil P*, Artiges E*, Lemaitre H, Gollier-Briant F, Wolke S, Vulser H et al. . Am J Psychiatry. (2015) 172(12):1215-23 PMID: 26085042.

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