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Child Psychiatry Branch

Publications

Selected Publications

Addington, A.M., Gauthier, J., Piton, A., Hamdan, F.F., Raymond, A., Gogtay, N., Miller, R., Tossell, J., Bakalar, J., Germain, G., Gochman, P., Long, R., Rapoport, J.L., and Rouleau, G.A., A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders. Mol Psychiatry, 2011. 16(3): p. 238-9.

Ahn K, An SS, Shugart YY, Rapoport JL. Common polygenic variation and risk for childhood-onset schizophrenia. Mol Psychiatry. 2014 Dec 16.

Ahn K, Gotay N, Andersen TM, Anvari AA, Gochman P, Lee Y, Sanders S, Guha S, Darvasi A, Glessner JT, Hakonarson H, Lencz T, State MW, Shugart YY, Rapoport JL. High rate of disease-related copy number variations in childhood onset schizophrenia. Mol Psychiatry. 2014 May;19(5):568-72.

Anvari AA, Friedman LA, Greenstein D, Gochman P, Gogtay N, Rapoport JL. Hippocampal volume change relates to clinical outcome in childhood-onset schizophrenia. Psychol Med. 2015 May 4:1-8

Chakravarty MM, Rapoport JL, Giedd JN, Raznahan A, Shaw P, Collins DL, Lerch JP, Gogtay N. Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: a longitudinal study. Hum Brain Mapp. 2015 Apr;36(4):1458-69.

Friedman LA, Rapoport JL. Brain development in ADHD. Curr Opin Neurobiol. 2015 Feb;30:106-11.

Giedd JN, Raznahan A, Alexander-Bloch A, Schmitt E, Gogtay N, Rapoport JL. Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development. Neuropsychopharmacology. 2015 Jan;40(1):43-9.

Gogtay N, Hua X, Stidd R, Boyle CP, Lee S, Weisinger B, Chavez A, Giedd JN, Clasen L, Toga AW,Rapoport JL, Thompson PM. Delayed white matter growth trajectory in young nonpsychotic siblings of patients with childhood-onset schizophrenia. Arch Gen Psychiatry. 2012 Sep;69(9):875-84.

Gogtay N, Weisinger B, Bakalar JL, Stidd R, Fernandez de la Vega O, Miller R, Clasen L, Greenstein D, Rapoport JL. Psychotic symptoms and gray matter deficits in clinical pediatric populations. Schizophr Res. 2012 Sep;140(1-3):149-54

Lin A, Clasen L, Lee NR, Wallace GL, Lalonde F, Blumenthal J, Giedd JN, Raznahan A. Mapping the stability of human brain asymmetry across five sex-chromosome aneuploidies. J Neurosci. 2015 Jan 7;35(1):140-5.

Mattai, A., Hosanagar, A., Weisinger, B., Greenstein, D., Stidd, R., Clasen, L., Lalonde, F., Rapoport, J., and Gogtay, N., Hippocampal volume development in healthy siblings of childhood-onset schizophrenia patients. Am J Psychiatry, 2011. 168(4): p. 427-35.

Rapoport JL. Pediatric psychopharmacology: too much or too little? World Psychiatry. 2013 Jun;12(2):118-23.

Rapoport JL. Prevention of schizophrenia: an impossible dream? Am J Psychiatry. 2013 Mar 1;170(3):245-7.

Rapoport JL, Giedd, JN., and Gogtay, N., Neurodevelopmental model of schizophrenia - update 2012. Mol Psychiatry, 2012 Dec;17(12):1228-38.

Rapoport JL, Gogtay N. Childhood onset schizophrenia: support for a progressive neurodevelopmental disorder. Int J Dev Neurosci. 2011 May;29(3):251-8.

Raznahan A. Sizing up the search for autism spectrum disorder (ASD) risk markers during prenatal and early postnatal life. J Am Acad Child Adolesc Psychiatry. 2014 Oct;53(10):1045-7.

Raznahan A, Greenstein D, Lee NR, Clasen LS, Giedd JN. Prenatal growth in humans and postnatal brain maturation into late adolescence. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11366-71.

Raznahan A, Greenstein, D., Lee, Y., Long, R., Clasen, L., Gochman, P., Addington, A., Giedd, J.N., Rapoport, J.L., and Gogtay, N., Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls. NeuroImage, 2011. 57(4): p. 1517-23.

Raznahan A, Lee NR, Greenstein D, Wallace GL, Blumenthal JD, Clasen LS, Giedd JN. Globally Divergent but Locally Convergent X- and Y-Chromosome Influences on Cortical Development. Cereb Cortex. 2014 Aug 21.

Raznahan A, Lee Y, Long R, Greenstein D, Clasen L, Addington A, Rapoport JL, Giedd JN. Common functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents. Mol Psychiatry. 2011 Sep;16(9):917-26.

Raznahan A, Lee Y, Stidd R, Long R, Greenstein D, Clasen L, Addington A, Gogtay N, Rapoport JL, Giedd JN. Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence. Proc Natl Acad Sci U S A 2010; 107(39): 16988-16993.

Raznahan A, Lerch J, Lee N, Greenstein D, Wallace G, Stockman M, Clasen P, Shaw P, Giedd JN. Patterns of coordinated anatomical change in human cortical development: A longitudinal neuroimaging study of maturational coupling, Neuron 2011 Dec 8;72(5):873-84.

Raznahan A, Lue Y, Probst F, Greenstein D, Giedd J, Wang C, Lerch J, Swerdloff R. Triangulating the sexually dimorphic brain through high-resolution neuroimaging of murine sex chromosome aneuploidies. Brain Struct Funct. 2014 Aug 22.

Raznahan A, Probst F, Palmert MR, Giedd JN, Lerch JP. High resolution whole brain imaging of anatomical variation in XO, XX, and XY mice. Neuroimage. 2013 Dec;83:962-8.

Raznahan A, Shaw PW, Lerch JP, Clasen LS, Greenstein D, Berman R, Pipitone J, Chakravarty MM, Giedd JN. Longitudinal four-dimensional mapping of subcortical anatomy in human development. Proc Natl Acad Sci U S A. 2014;111(4):1592-1597.

Raznahan A, Wallace GL, Antezana L, Greenstein D, Lenroot R, Thurm A, Gozzi M, Spence S, Martin A, Swedo SE, Giedd JN. Compared to what? Early brain overgrowth in autism and the perils of population norms. Biol Psychiatry. 2013 Oct 15;74(8):563-75.

Shaw P, Sharp W, Sudre G, Wharton A, Greenstein D, Raznahan A, Evans A, Chakravarty MM, Lerch JP, Rapoport J. Subcortical and cortical morphological anomalies as an endophenotype in obsessive-compulsive disorder. Mol Psychiatry. 2014 Feb 11.

Addington, A.M., Gauthier, J., Piton, A., Hamdan, F.F., Raymond, A., Gogtay, N., Miller, R., Tossell, J., Bakalar, J., Germain, G., Gochman, P., Long, R., Rapoport, J.L., and Rouleau, G.A., A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders. Mol Psychiatry, 2011. 16(3): p. 238-9.

Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Rapoport JL, Straub RE. GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss. Mol Psychiatry. 2005 Jun;10(6):581-8.

Addington AM, Gornick M, Shaw P, Seal J, Gogtay N, Greenstein D, Clasen L, Coffey M, Gochman P, Long R, Rapoport JL. Neuregulin 1 (8p12) and childhood-onset schizophrenia: susceptibility haplotypes for diagnosis and brain developmental trajectories. Mol Psychiatry. 2007 Feb;12(2):195-205.

Addington AM, Rapoport JL. Impact of advances in genetics in understanding developmental psychopathology. J Child Psychol Psychiatry. 2011 Nov 8.: 10.1111/j.1469-7610.2011.02478.x.

Ahn K, Gotay N, Andersen TM, Anvari AA, Gochman P, Lee Y, Sanders S, Guha S, Darvasi A, Glessner JT, Hakonarson H, Lencz T, State MW, Shugart YY, Rapoport JL. High rate of disease-related copy number variations in childhood onset schizophrenia. Mol Psychiatry. 2014 May;19(5):568-72.

Alexander-Bloch A, Raznahan A, Bullmore E, Giedd J. The convergence of maturational change and structural covariance in human cortical networks. J Neurosci. 2013 Feb 13;33(7):2889-99.

Alexander-Bloch AF, Reiss PT, Rapoport J, McAdams H, Giedd JN, Bullmore ET, Gogtay N. Abnormal Cortical Growth in Schizophrenia Targets Normative Modules of Synchronized Development. Biol Psychiatry. 2014 Feb 22.

Alexander-Bloch AF, Vértes PE, Stidd R, Lalonde F, Clasen L, Rapoport J, Giedd J, Bullmore ET, Gogtay N. The anatomical distance of functional connections predicts brain network topology in healthand schizophrenia. Cereb Cortex. 2013 Jan;23(1):127-38.

Bakalar JL, Greenstein DK, Clasen L, Tossell JW, Miller R, Evans AC, Mattai AA, Rapoport JL, Gogtay N. General absence of abnormal cortical asymmetry in childhood-onset schizophrenia: a longitudinal study. Schizophr Res. 2009 Nov;115(1):12-6. Epub 2009 Sep 5.

Blumenthal JD, Baker EH, Lee NR, Wade B, Clasen LS, Lenroot RK, Giedd JN. Brain morphological abnormalities in 49, XXXXY syndrome: A pediatric magnetic resonance imaging study. NeuroImage: Clinical, Volume 2, 2013, Pages 197–203.

Blumenthal JD, Zijdenbos A, Molloy E, Giedd JN. Motion artifact in magnetic resonance imaging: implications for automated analysis. Neuroimage. 2002 May;16(1):89-92.

Bobb AJ, Addington AM, Sidransky E, Gornick MC, Lerch JP, Greenstein DK, Clasen LS, Sharp WS, Inoff-Germain G, Wavrant-De Vrieze F, Arcos-Burgos M, Straub RE, Hardy JA, Castellanos FX, Rapoport JL. Support for association between ADHD and two candidate genes: NET1 and DRD1. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5;134(1):67-72.

Bobb AJ, Castellanos FX, Addington AM, Rapoport JL. Molecular genetic studies of ADHD: 1991 to 2004. Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132(1):109-25.

Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS, Blumenthal JD, James RS, Ebens CL, Walter JM, Zijdenbos A, Evans AC, Giedd JN, Rapoport JL. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. JAMA. 2002 Oct 9;288(14):1740-8.

Castellanos FX, Sharp WS, Gottesman RF, Greenstein DK, Giedd JN, Rapoport JL. Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder. Am J Psychiatry. 2003 Sep;160(9):1693-6.

David, C.N., Greenstein, D., Clasen, L., Gochman, P., Miller, R., Tossell, J.W., Mattai, A.A., Gogtay, N., and Rapoport, J.L., Childhood onset schizophrenia: high rate of visual hallucinations. J Am Acad Child Adolesc Psychiatry, 2011. 50(7): p. 681-686 e3.

Driver DI, Gogtay N, Rapoport JL. Childhood onset schizophrenia and early onset schizophrenia spectrum disorders. Child Adolesc Psychiatr Clin N Am. 2013 Oct;22(4):539-55.

Giedd JN. Structural magnetic resonance imaging of the adolescent brain. Ann N Y Acad Sci. 2004 Jun;1021:77-85.

Giedd JN. The anatomy of mentalization: a view from developmental neuroimaging. Bull Menninger Clin. 2003 Spring;67(2):132-42.

Giedd JN, Clasen LS, Lenroot R, Greenstein D, Wallace GL, Ordaz S, Molloy EA, Blumenthal JD, Tossell JW, Stayer C, Samango-Sprouse CA, Shen D, Davatzikos C, Merke D, Chrousos GP. Puberty-related influences on brain development. Mol Cell Endocrinol. 2006 Jul 25;254-255:154-62.

Giedd JN, Clasen LS, Wallace GL, Lenroot RK, Lerch JP, Wells EM, Blumenthal JD, Nelson JE, Tossell JW, Stayer C, Evans AC, Samango-Sprouse CA. XXY (Klinefelter syndrome): a pediatric quantitative brain magnetic resonance imaging case-control study. Pediatrics. 2007 Jan;119(1):e232-40.

Giedd JN, Lalonde FM, Celano MJ, White SL, Wallace GL, Lee NR, Lenroot RK. Anatomical brain magnetic resonance imaging of typically developing children and adolescents. J Am Acad Child Adolesc Psychiatry. 2009 May;48(5):465-70. Review.

Giedd JN, Lenroot RK, Shaw P, Lalonde F, Celano M, White S, Tossell J, Addington A, Gogtay N. Trajectories of anatomic brain development as a phenotype. Novartis Found Symp. 2008;289:101-12; discussion 112-8, 193-5. Review.

Giedd JN, Schmitt JE, Neale MC. Structural brain magnetic resonance imaging of pediatric twins. Hum Brain Mapp, 2007; 28(6):474-481.

Gochman PA, Greenstein D, Sporn A, Gogtay N, Keller B, Shaw P, Rapoport JL. IQ stabilization in childhood-onset schizophrenia. Schizophr Res. 2005 Sep 15;77(2-3):271-7.

Gochman PA, Greenstein D, Sporn A, Gogtay N, Nicolson R, Keller A, Lenane M, Brookner F, Rapoport JL. Childhood onset schizophrenia: familial neurocognitive measures. Schizophr Res. 2004 Nov 1;71(1):43-7.

Gogtay, N., Cortical brain development in schizophrenia: insights from neuroimaging studies in childhood-onset schizophrenia. Schizophr Bull, 2008. 34(1): p. 30-6.

Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaituzis AC, Nugent TF 3rd, Herman DH, Clasen LS, Toga AW, Rapoport JL, Thompson PM. Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci U S A. 2004 May 25;101(21):8174-9.

Gogtay N, Giedd J, Rapoport JL. Brain development in healthy, hyperactive, and psychotic children. Arch Neurol. 2002 Aug;59(8):1244-8. Review.

Gogtay N, Hua X, Stidd R, Boyle CP, Lee S, Weisinger B, Chavez A, Giedd JN, Clasen L, Toga AW, Rapoport JL, Thompson PM. Delayed white matter growth trajectory in young nonpsychotic siblings of patients with childhood-onset schizophrenia. Arch Gen Psychiatry. 2012 Sep;69(9):875-84.

Gogtay N, Lu A, Leow AD, Klunder AD, Lee AD, Chavez A, Greenstein D, Giedd JN, Toga AW, Rapoport JL, Thompson PM. Three-dimensional brain growth abnormalities in childhood-onset schizophrenia visualized by using tensor-based morphometry. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15979-84. Epub 2008 Oct 13.

Gogtay N, Nugent TF 3rd, Herman DH, Ordonez A, Greenstein D, Hayashi KM, Clasen L, Toga AW, Giedd JN, Rapoport JL, Thompson PM. Dynamic mapping of normal human hippocampal development. Hippocampus. 2006;16(8):664-72.

Gogtay, N. and Rapoport, J., Clozapine use in children and adolescents. Expert Opin Pharmacother, 2008. 9(3): p. 459-65.

Gogtay, N. and Rapoport, J.L., Childhood-onset schizophrenia: insights from neuroimaging studies. J Am Acad Child Adolesc Psychiatry, 2008. 47(10): p. 1120-4.

Gogtay N, Sporn A, Alfaro CL, Mulqueen A, Rapoport JL. Clozapine-induced akathisia in children with schizophrenia. J Child Adolesc Psychopharmacol. 2002 Winter;12(4):347-9.

Gogtay N, Sporn A, Clasen LS, Greenstein D, Giedd JN, Lenane M, Gochman PA, Zijdenbos A, Rapoport JL. Structural brain MRI abnormalities in healthy siblings of patients with childhood-onset schizophrenia. Am J Psychiatry. 2003 Mar;160(3):569-71.

Gogtay N, Sporn A, Clasen LS, Nugent TF 3rd, Greenstein D, Nicolson R, Giedd JN, Lenane M, Gochman P, Evans A, Rapoport JL. Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychoses. Arch Gen Psychiatry. 2004 Jan;61(1):17-22.

Gogtay, N., Vyas, N.S., Testa, R., Wood, S.J., and Pantelis, C., Age of onset of schizophrenia: perspectives from structural neuroimaging studies. Schizophr Bull, 2011. 37(3): p. 504-13.

Gornick MC, Addington AM, Shaw P, Bobb AJ, Sharp W, Greenstein D, Arepalli S, Castellanos FX, Rapoport JL. Association of the dopamine receptor D4 (DRD4) gene 7-repeat allele with children with attention-deficit/hyperactivity disorder (ADHD): An update. Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 14;144B(3):379-382.

Gornick MC, Addington AM, Sporn A, Gogtay N, Greenstein D, Lenane M, Gochman P, Ordonez A, Balkissoon R, Vakkalanka R, Weinberger DR, Rapoport JL, Straub RE. Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS). J Autism Dev Disord. 2005 Dec;35(6):831-8.

Greenstein D, Kataria R, Gochman P, Dasgupta A, Malley JD, Rapoport J, Gogtay N. Looking for Childhood-Onset Schizophrenia: Diagnostic Algorithms for Classifying Children and Adolescents with Psychosis. J Child Adolesc Psychopharmacol. 2014 Jul 14.

Greenstein D, Lerch J, Shaw P, Clasen L, Giedd J, Gochman P, Rapoport J, Gogtay N. Childhood onset schizophrenia: cortical brain abnormalities as young adults. J Child Psychol Psychiatry. 2006 Oct;47(10):1003-12.

Greenstein, D.K., Wolfe, S., Gochman, P., Rapoport, J.L., and Gogtay, N., Remission status and cortical thickness in childhood-onset schizophrenia. J Am Acad Child Adolesc Psychiatry, 2008. 47(10): p. 1133-40.

Hanley AP, Blumenthal JD, Lee NR, Baker EH, Clasen LS, Giedd JN. Brain and behavior in 48, XXYY syndrome. NeuroImage: Clinical 8, 133-139.

Inoff-Germain G, Rodriguez RS, Torres-Alcantara S, Diaz-Jimenez MJ, Swedo SE, Rapoport JL. An immunological marker (D8/17) associated with rheumatic fever as a predictor of childhood psychiatric disorders in a community sample. J Child Psychol Psychiatry. 2003 Jul;44(5):782-90.

Keller A, Castellanos FX, Vaituzis AC, Jeffries NO, Giedd JN, Rapoport JL. Progressive loss of cerebellar volume in childhood-onset schizophrenia. Am J Psychiatry. 2003 Jan;160(1):128-33.

Keller A, Jeffries NO, Blumenthal J, Clasen LS, Liu H, Giedd JN, Rapoport JL. Corpus callosum development in childhood-onset schizophrenia. Schizophr Res. 2003 Jul 1;62(1-2):105-14.

Lee, N.R., Lopez, K., Adeyemi, E., and Giedd, J.N. (2011). Sex chromosome aneuploidies: A window for examining the effects of the X and Y chromosomes on speech, language, and social development. International Review of Research in Developmental Disabilities, 40, 139-180.

Lee N.R., Raznahan A, Wallace GL, Alexander-Bloch A, Clasen LS, Lerch JP, Giedd JN. Anatomical coupling among distributed cortical regions in youth varies as a function of individual differences in vocabulary abilities. Hum Brain Mapp. 2014 May;35(5):1885-95

Lee N.R., Wallace GL, Adeyemi EI, Lopez KC, Blumenthal JD, Clasen LS, Giedd JN. Dosage effects of X and Y chromosomes on language and social functioning in children withsupernumerary sex chromosome aneuploidies: implications for idiopathic language impairment and autism spectrum disorders. J Child Psychol Psychiatry. 2012 Oct;53(10):1072-81.

Lee, N.R., Wallace, G.L. Clasen, L.S. Lenroot, R.K., Blumenthal, J. D., White, S.L., Celano, M.J., Giedd, J.D. (2011). Executive Function in Young Males with Klinefelter (XXY) Syndrome with and without Comorbid Attention-Deficit/Hyperactivity Disorder. Journal of the International Neuropsychological Society, 17, 522-530.

Lee N.R., Wallace GL, Raznahan A, Clasen LS, Giedd JN. Trail making test performance in youth varies as a function of anatomical coupling between the prefrontal cortex and distributed cortical regions. Front Psychol. 2014 Jul 1;5:496.

Lenroot RK, Blumenthal JD, Wallace GL, Clasen LS, Lee NR, Giedd JN. A case-control study of brain structure and behavioral characteristics in 47,XXX syndrome. Genes Brain Behav. 2014 Nov;13(8):841-9.

Lenroot RK, Giedd JN. Brain development in children and adolescents: insights from anatomical magnetic resonance imaging. Neurosci Biobehav Rev. 2006;30(6):718-29.

Lenroot RK, Gogtay N, Greenstein DK, Wells EM, Wallace GL, Clasen LS, Blumenthal JD, Lerch J, Zijdenbos AP, Evans AC, Thompson PM, Giedd JN. Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage. 2007 Jul 15;36(4):1065-73.

Lenroot, R., Lee, N.R., and Giedd, J. (2009). Effects of sex chromosome aneuploidies on brain development: Evidence from neuroimaging studies. Developmental Disabilities Research Reviews, 15, 318-327.

Lerch JP, Worsley K, Shaw WP, Greenstein DK, Lenroot RK, Giedd J, Evans AC. Mapping anatomical correlations across cerebral cortex (MACACC) using cortical thickness from MRI. Neuroimage. 2006 Jul 1;31(3):993-1003.

Mackie S, Shaw P, Lenroot R, Pierson R, Greenstein DK, Nugent TF, 3rd, Sharp WS, Giedd JN, Rapoport JL. Cerebellar development and clinical outcome in attention deficit hyperactivity disorder. Am J Psychiatry, 2007; 164(4):647-655.

Mattai, A., Hosanagar, A., Weisinger, B., Greenstein, D., Stidd, R., Clasen, L., Lalonde, F., Rapoport, J., and Gogtay, N., Hippocampal volume development in healthy siblings of childhood-onset schizophrenia patients. Am J Psychiatry, 2011. 168(4): p. 427-35.

Mattai, A., Miller, R., Weisinger, B., Greenstein, D., Bakalar, J., Tossell, J., David, C.N., Wasserman, E.M., Rapaport, J., and Gogtay, N., Tolerability of transcranial direct current stimulation in childhood onset schizophrenia. Brain Stimulation, 2011.

Mattai AA, Tossell J, Greenstein DK, Addington A, Clasen LS, Gornick MC, Seal J, Inoff-Germain G, Gochman PA, Lenane M, Rapoport JL, Gogtay N. Sleep disturbances in childhood-onset schizophrenia. Schizophr Res. 2006 Sep;86(1-3):123-9.

Mattai, A.A., Weisinger, B., Greenstein, D., Stidd, R., Clasen, L., Miller, R., Tossell, J.W., Rapoport, J.L., and Gogtay, N., Normalization of cortical gray matter deficits in nonpsychotic siblings of patients with childhood-onset schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry, 2011. 50(7): p. 697-704.

Miller, R., Caponi, J., Sevy, S. and Robinson, D. (2005). The insight-adherence-abstinence triad: An integrated treatment focus for cannabis using first episode schizophrenia patients. Bulletin of the Menninger Clinic, 69, 3, 220-236.

Miller, R., Mason, S.E. (Eds.). (2011) Diagnosis Schizophrenia: A comprehensive resource for patients, families and healthcare professionals. 2nd ed. New York: Columbia University Press.

Miller, R. and Mason, S.E. (2005). Shame and guilt in first episode schizophrenia. Journal of Contemporary Psychotherapy, 35, (2), 211-221.

Miller, R. and Mason, S.E. (2004). Cognitive enhancement therapy: A treatment strategy for first- episode patients. Bulletin of the Menninger Clinic, 68(3), 213-230.

Miller, R. and Mason, S.E. (Eds.). (2002) Diagnosis Schizophrenia: A comprehensive resource book for patients, families and healthcare professionals. New York : Columbia University Press.

Miller, R. and McCormack, J. (2006) Faith and religious delusions in first-episode schizophrenia. Social Work in Mental Health, 4, 4, 37-50.

Miller, R., Ream, G., McCormack, J., Gunduz-Bruce, H., Sevy, S., Robinson, D. (2009). A prospective study of cannabis use as a risk factor for non-adherence and treatment dropout in first- episode schizophrenia. Schizophrenia Research, 113, 138-144.

Nicolson R, Brookner FB, Lenane M, Gochman P, Ingraham LJ, Egan MF, Kendler KS, Pickar D, Weinberger DR, Rapoport JL. Parental schizophrenia spectrum disorders in childhood-onset and adult-onset schizophrenia. Am J Psychiatry. 2003 Mar;160(3):490-5.

Nugent TF 3rd, Herman DH, Ordonez A, Greenstein D, Hayashi KM, Lenane M, Clasen L, Jung D, Toga AW, Giedd JN, Rapoport JL, Thompson PM, Gogtay N. Dynamic mapping of hippocampal development in childhood onset schizophrenia. Schizophr Res. 2007 Feb;90(1-3):62-70.

Ordaz SJ, Lenroot RK, Wallace GL, Clasen LS, Blumenthal JD, Schmitt JE, Giedd JN. Are there differences in brain morphometry between twins and unrelated singletons? A pediatric MRI study. Genes Brain Behav. 2010 Apr;9(3):288-95. Epub 2009 Nov 25.

Ordonez AE, Bobb A, Greenstein D, Baker N, Sporn A, Lenane M, Malaspina D, Rapoport J, Gogtay N. Lack of evidence for elevated obstetric complications in childhood onset schizophrenia. Biol Psychiatry. 2005 Jul 1;58(1):10-5.

Rapoport JL. Pediatric psychopharmacology: too much or too little? World Psychiatry. 2013 Jun;12(2):118-23.

Rapoport JL. Prevention of schizophrenia: an impossible dream? Am J Psychiatry. 2013 Mar 1;170(3):245-7.

Rapoport JL, Addington A, Frangou S. The neurodevelopmental model of schizophrenia: what can very early onset cases tell us? Curr Psychiatry Rep. 2005 Apr;7(2):81-2.

Rapoport JL, Addington AM, Frangou S, Psych MR. The neurodevelopmental model of schizophrenia: update 2005. Mol Psychiatry. 2005 May;10(5):434-49.

Rapoport, J., Chavez, A., Greenstein, D., Addington, A., and Gogtay, N., Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited. J Am Acad Child Adolesc Psychiatry, 2009. 48(1): p. 10-8.

Rapoport JL, Giedd JN, Gogtay N. Neurodevelopmental model of schizophrenia: update 2012. Mol Psychiatry. 2012 Dec;17(12):1228-38.

Rapoport JL, Gogtay N. Brain neuroplasticity in healthy, hyperactive and psychotic children: insights from neuroimaging. Neuropsychopharmacology. 2008 Jan;33(1):181-97. Epub 2007 Sep 12. Review.

Rapoport JL, Inoff-Germain G. Responses to methylphenidate in Attention-Deficit/Hyperactivity Disorder and normal children: update 2002. J Atten Disord. 2002;6 Suppl 1:S57-60. Review.

Rapoport JL, Shaw P. Defining the contribution of genetic risk to structural and functional anomalies in ADHD. J Am Acad Child Adolesc Psychiatry. 2008 Jan;47(1):2-3.

Raznahan A, Cutter W, Lalonde F, Robertson D, Daly E, Conway GS, Skuse DH, Ross J, Lerch JP, Giedd JN, Murphy DG. Cortical anatomy in human X monosomy. Neuroimage 2010; 49(4): 2915-2923.

Raznahan A, Giedd J, Bolton P. Neurostructural Endophenotypes In Autism Spectrum Disorders. In: Ritsner MS (ed). The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes, 1st edn, vol. 2. Springer: Berlin, 2009, pp 145-170.

Raznahan, A., Greenstein, D., Lee, Y., Long, R., Clasen, L., Gochman, P., Addington, A., Giedd, J.N., Rapoport, J.L., and Gogtay, N., Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls. NeuroImage, 2011. 57(4): p. 1517-23.

Raznahan A, Lee Y, Long R, Greenstein D, Clasen L, Addington A, Rapoport JL, Giedd JN. Common functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents. Mol Psychiatry. 2011. Sep;16(9):917-26.

Raznahan A, Lee Y, Long R, Greenstein D, Clasen L, Addington A, Rapoport JL, Giedd JN. Common functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents. Mol Psychiatry. 2010 Jul 13.

Raznahan A, Lee Y, Stidd R, Long R, Greenstein D, Clasen L, Addington A, Gogtay N, Rapoport JL, Giedd JN. Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence. Proc Natl Acad Sci U S A 2010; 107(39): 16988-16993.

Raznahan A, Lee Y, Vaituzis C, Tran L, Mackie S, Tiemeier H, Clasen L, Lalonde F, Greenstein D, Pierson R, Giedd JN. Allelic variation within the putative autism spectrum disorder risk gene homeobox A1 andcerebellar maturation in typically developing children and adolescents. Autism Res. 2012 Apr;5(2):93-100.

Raznahan A, Lerch JP, Lee N, Greenstein D, Wallace GL, Stockman M, Clasen L, Shaw PW, Giedd JN. Patterns of coordinated anatomical change in human cortical development: a longitudinalneuroimaging study of maturational coupling. Neuron. 2011 Dec 8;72(5):873-84.

Raznahan A, Probst F, Palmert MR, Giedd JN, Lerch JP. High resolution whole brain imaging of anatomical variation in XO, XX, and XY mice. Neuroimage. 2013 Dec;83:962-8.

Raznahan A, Shaw P, Lalonde F, Stockman M, Wallace GL, Greenstein D, Clasen L, Gogtay N, Giedd JN. How does your cortex grow? J Neurosci 2011; 31(19): 7174-7177.

Raznahan A, Shaw PW, Lerch JP, Clasen LS, Greenstein D, Berman R, Pipitone J, Chakravarty MM, Giedd JN. Longitudinal four-dimensional mapping of subcortical anatomy in human development. Proc Natl Acad Sci U S A. 2014;111(4):1592-1597.

Raznahan A, Wallace GL, Antezana L, Greenstein D, Lenroot R, Thurm A, Gozzi M, Spence S, Martin A, Swedo SE, Giedd JN. Compared to what? Early brain overgrowth in autism and the perils of population norms. Biol Psychiatry. 2013 Oct 15;74(8):563-75.

Schmitt JE, Wallace GL, Rosenthal MA, Molloy EA, Ordaz S, Lenroot R, Clasen LS, Blumenthal JD, Kendler KS, Neale MC, Giedd JN. A multivariate analysis of neuroanatomic relationships in a genetically informative pediatric sample. Neuroimage. 2007 Mar;35(1):70-82.

Seal JL, Gornick MC, Gogtay N, Shaw P, Greenstein DK, Coffey M, Gochman PA, Stromberg T, Chen Z, Merriman B, Nelson SF, Brooks J, Arepalli S, Wavrant-De Vrieze F, Hardy J, Rapoport JL, Addington AM. Segmental uniparental isodisomy on 5q32-qter in a patient with childhood-onset schizophrenia. J Med Genet. 2006 Nov;43(11):887-92.

Sharp WS, Gottesman RF, Greenstein DK, Ebens CL, Rapoport JL, Castellanos FX. Monozygotic twins discordant for attention-deficit/hyperactivity disorder: ascertainment and clinical characteristics. J Am Acad Child Adolesc Psychiatry. 2003 Jan;42(1):93-7.

Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D, Clasen L, Evans A, Giedd J, and Rapoport JL. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. PNAS, 2007, 104:49, 19649-19654.

Shaw P, Gogtay N, Rapoport J. Childhood psychiatric disorders as anomalies in neurodevelopmental trajectories. Hum Brain Mapp. 2010 Jun;31(6):917-25.

Shaw P, Greenstein D, Lerch J, Clasen L, Lenroot R, Gogtay N, Evans A, Rapoport J, Giedd J. Intellectual ability and cortical development in children and adolescents. Nature. 2006 Mar 30;440(7084):676-9.

Shaw P, Kabani NJ, Lerch JP, Eckstrand K, Lenroot R, Gogtay N, Greenstein D, Clasen L, Evans A, Rapoport JL, Giedd JN, Wise SP. Neurodevelopmental trajectories of the human cerebral cortex. J Neurosci. 2008 Apr 2;28(14):3586-94.

Shaw P, Lalonde F, Lepage C, Rabin C, Eckstrand K, Sharp W, Greenstein D, Evans A, Giedd JN, Rapoport J. Development of cortical asymmetry in typically developing children and its disruption in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2009 Aug;66(8):888-96.

Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, Giedd J, Castellanos FX, Rapoport J. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2006 May;63(5):540-9.

Shaw P, Lerch JP, Pruessner JC, Taylor KN, Rose AB, Greenstein D, Clasen L, Evans A, Rapoport JL, Giedd JN. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol, 2007; 6(6):494-500.

Shaw P, Rapoport JL. Decision making about children with psychotic symptoms: using the best evidence in choosing a treatment. J Am Acad Child Adolesc Psychiatry. 2006 Nov;45(11):1381-6.

Shaw P, Sharp W, Sudre G, Wharton A, Greenstein D, Raznahan A, Evans A, Chakravarty MM, Lerch JP, Rapoport J. Subcortical and cortical morphological anomalies as an endophenotype in obsessive-compulsive disorder. Mol Psychiatry. 2014 Feb 11.

Shaw P, Sporn A, Gogtay N, Overman GP, Greenstein D, Gochman P, Tossell JW, Lenane M, Rapoport JL. Childhood-onset schizophrenia: A double-blind, randomized clozapine-olanzapine comparison. Arch Gen Psychiatry. 2006 Jul;63(7):721-30.

Shaw P, Wallace GL, Addington A, Evans A, Rapoport J, Giedd JN. Effects of the Val158Met catechol-O-methyltransferase polymorphism on cortical structure in children and adolescents. Mol Psychiatry. 2009 Apr;14(4):348-9.

Sporn AL, Addington AM, Gogtay N, Ordonez AE, Gornick M, Clasen L, Greenstein D, Tossell JW, Gochman P, Lenane M, Sharp WS, Straub RE, Rapoport JL. Pervasive developmental disorder and childhood-onset schizophrenia: comorbid disorder or a phenotypic variant of a very early onset illness? Biol Psychiatry. 2004 May 15;55(10):989-94.

Sporn AL, Addington AM, Reiss AL, Dean M, Gogtay N, Potocnik U, Greenstein D, Hallmayer J, Gochman P, Lenane M, Baker N, Tossell J, Rapoport JL. 22q11 deletion syndrome in childhood onset schizophrenia: an update. Mol Psychiatry. 2004 Mar;9(3):225-6.

Sporn AL, Bobb AJ, Gogtay N, Stevens H, Greenstein DK, Clasen LS, Tossell JW, Nugent T, Gochman PA, Sharp WS, Mattai A, Lenane MC, Yanovski JA, Rapoport JL.. Hormonal correlates of clozapine-induced weight gain in psychotic children: an exploratory study. J Am Acad Child Adolesc Psychiatry. 2005 Sep;44(9):925-33.

Sporn AL, Greenstein DK, Gogtay N, Jeffries NO, Lenane M, Gochman P, Clasen LS, Blumenthal J, Giedd JN, Rapoport JL. Progressive brain volume loss during adolescence in childhood-onset schizophrenia. Am J Psychiatry. 2003 Dec;160(12):2181-9.

Sporn AL, Greenstein DK, Gogtay N, Sailer F, Hommer DW, Rawlings R, Nicolson R, Egan MF, Lenane M, Gochman P, Weinberger DR, Rapoport JL. Childhood-onset schizophrenia: smooth pursuit eye-tracking dysfunction in family members. Schizophr Res. 2005 Mar 1;73(2-3):243-52.

Sporn A, Gogtay N, Ortiz-Aguayo R, Alfaro C, Tossell J, Lenane M, Gochman P, Rapoport JL. Clozapine-induced neutropenia in children: management with lithium carbonate. J Child Adolesc Psychopharmacol. 2003 Fall;13(3):401-4.

Stayer C, Sporn A, Gogtay N, Tossell JW, Lenane M, Gochman P, Greenstein D, Sharp W, Rapoport JL. Multidimensionally impaired: the good news. J Child Adolesc Psychopharmacol. 2005 Jun;15(3):510-9.

Stayer C, Sporn A, Gogtay N, Tossell J, Lenane M, Gochman P, Rapoport JL. Looking for childhood schizophrenia: case series of false positives. J Am Acad Child Adolesc Psychiatry. 2004 Aug;43(8):1026-9.

Tossell JW, Greenstein DK, Davidson AL, Job SB, Gochman P, Lenane M, Nugent Iii TF, Gogtay N, Sporn AL, Rapoport JL. Stimulant drug treatment in childhood-onset schizophrenia with comorbid ADHD: an open-label case series. J Child Adolesc Psychopharmacol. 2004 Fall;14(3):448-54.

Vidal CN, Rapoport JL, Hayashi KM, Geaga JA, Sui Y, McLemore LE, Alaghband Y, Giedd JN, Gochman P, Blumenthal J, Gogtay N, Nicolson R, Toga AW, Thompson PM. Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia. Arch Gen Psychiatry. 2006 Jan;63(1):25-34.

Wade BSC, Joshi SH, Reuter M, Blumenthal JD, Toga AW, Thompson PM, Giedd JN. Effects of sex chromosome dosage on corpus callosum morphology in supernumerary sex chromosome aneuploidies. Biology of Sex Differences 5(1), 16.

Wade BS, Stockman M, McLaughlin MJ, Raznahan A, Lalonde F, Giedd JN. Improved corpus callosum area measurements by analysis of adjoining parasagittal slices. Psychiatry Res. 2013 Mar 30;211(3):221-5.

Wallace, G.L./ Lee, N.R.*, Prom-Wormley, E.C./Medland, S.E., Lenroot, R.K., Clasen, L.C., Schmitt, J.E., Neale, M.C., Giedd, J. N. (2010). A bivariate twin study of regional brain volume and verbal and nonverbal intellectual skills during childhood and adolescence. Behavior Genetics, 40, 125-134. (*Co-first authors)

Wallace GL, Schmitt E J, Lenroot R, Viding E, Ordaz S, Rosenthal MA, Molloy EA, Clasen LS, Kendler KS, Neale MC, Giedd JN. A pediatric twin study of brain morphometry. J Child Psychol Psychiatry. 2006 Oct;47(10):987-93.

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