Dr. Carlos A. Zarate, Jr., MD
Chief, Experimental Therapeutics and Pathophysiology Branch
Dr. Carlos A. Zarate, Jr., MD, Chief of the Experimental Therapeutics and Pathophysiology Branch, earned his medical degree from the Catholic University of Cordoba in Argentina. He completed a clinical psychopharmacology fellowship at McLean Hospital in 1993, after which he remained on staff until 1998. In 1998, Dr. Zarate joined the faculty at the University of Massachusetts Medical School. In 2001, Dr. Zarate joined the Mood and Anxiety Disorders program at the NIMH and, in 2009, formed the Experimental Therapeutics and Pathophysiology Branch (ETPB). A multidisciplinary translational research team conducts the research in the ETPB. The Branch also provides training to develop the next generation of clinical translational researchers.
Dr. Zarate's current research focus is on developing novel medications for treatment-resistant depression and bipolar disorder. His areas of expertise include biological and pharmacological aspects of mood disorders in adults. The ETPB conducts proof-of-concept studies utilizing novel compounds and biomarkers (magnetoencephalography and polysomnography, positron emission tomography, functional MRI and magnetic resonance spectroscopy) to identify potentially relevant drug targets and biosignatures of treatment response. Dr. Zarate has published more than 200 papers on these topics.
Awards & Honors
Dr. Zarate’s achievements and awards include the Ethel-DuPont Warren Award and Livingston Awards, Consolidated Department of Psychiatry, Harvard Medical School; Outstanding Psychiatrist Research Award, Massachusetts Psychiatric Association; Program for Minority Research Training in Psychiatry, American Psychiatric Association; NIH-NIMH Travel Award, 1994; American College of Neuropsychopharmacology Travel Awards 1994 and 1995; the National Alliance for Research on Schizophrenia and Depression Young Investigator Award, 1996-1998; The Diversity and Advocacy Award, Hispanic Research Initiative Committee, NIMH, 2002; the Mentor of the Year, Intramural Research Program NIMH, 2004; the Supervisor of the Year NIMH, 2005; the National Alliance for Research on Schizophrenia and Depression Independent Investigator Award, 2005; the NIH Director’s Award-Scientific/Medical, 2009, and the Brain & Behavior Research Foundation Award for Bipolar Mood Disorder Research (NARSAD), 2011; The National Institute of Health Director’s Award—Scientific/Medical Achievement, 2013; and, the Mogens Schou Research Award: Bipolar Disorder, 2013.
Carlos A. Zarate, M.D.
Clinical Trials, Neuropsychopharmacology, Psychiatry
Rodrigo Machado-Vieira, M.D., Ph.D.
Biomarkers, Clinical Trials, Psychiatry
Allison Nugent, Ph.D.
Physics, Imaging, Development of functional and structural MRI techniques
Lawrence Park, M.D.
Clinical Trials, Neuromodulation, Psychiatry
Nancy Brutsche, M.S.N.
Clinical Nurse Specialist
Madeline Gupta, R.N., M.A.
Immaculata Ukoh, M.S.N., C.R.N.P.
Rezvan Ameli, Ph.D.
Yamila Carmona, MA
Clinical Psychology Research
Wallace Duncan, Ph.D.
Neuroscience, Sleep, Circadian Biology
Brenda Gray, Th.M.
Clinical Care Coordinator
Libby Jolkovsky, M.S.
Psychology, Community Relations & Recruitment
Eva Kakoza, B.S.
David Luckenbaugh, M.A.
Alex Noury, M.A.
Protocol Coordinator, Regulatory
Joanna Szczepanik, M.A.
Clinical Psychology, Cognitive Science, Neuroscience
Tyler Ard, Ph.D.
Elizabeth Ballard, Ph.D.
Jessica Ihne, Ph.D.
Níall Lally, M.Sc.
Valeria Martinez, M.S.
Clinical Health Psychology & Behavioral Medicine
Mark Niciu, M.D., Ph.D.
Minkyung Park, M.D.
Erica Richards, M.D., Ph.D.
Intramural Research Training Awardees (IRTAs)