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Section on Neurobiology of Fear and Anxiety

Curriculum Vitae of Salvatore (Sam) Torrisi

Education

PhD Neuroscience Interdepartmental Program
Summer, 2013
University of California, Los Angeles
695 Young Drive South
Los Angeles, CA 90095
Primary advisor: Dr. Lori Altshuler of the UCLA Mood Disorders Research Program.
Dissertation committee: L Altshuler, S Bookheimer, E London, M Monti, J van Horn

MA Applied Linguistics
Spring, 2007
University of California, Los Angeles
3300 Rolfe Hall
Los Angeles, CA 90095
Advisors: John Schumann, Charles Goodwin

MFA Music Composition/New Media
December, 2003
California Institute of the Arts
24700 McBean Pkwy
Valencia, CA 91355
Advisors: James Tenney, David Rosenboom, Sara Roberts, Mark Trayle

BA Interdisciplinary Arts and Performance (Media Studies)
May, 2001
Arizona State University West
4701 W. Thunderbird Rd
Phoenix, AZ 85069
Advisors: Richard Lerman, Daniel Lentz.
Graduated Summa Cum Laude

Research Experience

Section on the Neurobiology of Fear and Anxiety
PIs: Christian Grillon, Monique Ernst
National Institute of Mental Health
15K North Drive
Bethesda, MD 20892
2016 – current
Research Fellow
3 and 7 Tesla functional neuroimaging and connectivity analyses of the anxiety network.

Section on the Neurobiology of Fear and Anxiety
PIs: Christian Grillon, Monique Ernst
National Institute of Mental Health
15K North Drive
Bethesda, MD 20892
2013 – 2016
Postdoctoral Fellow
3 and 7 Tesla functional neuroimaging and connectivity analyses of the anxiety network.

Mood Disorders Research Program
PI: Lori Altshuler
300 UCLA Medical Plaza, Suite 1544
April 2009 – Summer 2013
Functional neuroimaging and connectivity analyses of the euthymic mood state of Bipolar Disorder.

Graduate Student Researcher
PI: Stephanie A. White.
White Lab, Department of Physiological Science
UCLA
Sept 2005–June 2007
Technical assistance, hardware implementation and behavioral analysis for a songbird laboratory.

Internships

Internship rotation on inpatient units of UCLA
Neuropsychiatric Hospital under the directorship of Dr. Laurie Casaus.
August 1 – Sept 1, 2011.

Externship rotation at outpatient UCLA Mood Disorders Clinic
Semel Institute, UCLA under the directorship of Dr. Michael Gitlin.
August 1 – Sept. 1, 2011.

Cortical Thickness of Methamphetamine Addicts.
PI: Edythe London
Semel Institute, UCLA
Jan 2009–April 2009
Cortical thickness correlated with measures of impulsivity from the Balloon Analogue Risk Task (BART).

Cross-Correlation of Observed Social Interactions.
PI: Marco Iacoboni.
Ahmanson Lovelace Brain Mapping Center, UCLA
Sept 2007–March 2008
Project: Intersubject cross-correlational data mining of people observing video stimuli of social
interactions. Lit review of data-driven fMRI analyses and unique behavioral coding of video stimuli.

Anthropology

Ethnography of Frontotemporal Dementia (FTD).
PI: Alan P. Fiske.
Departments of Applied Linguistics, Anthropology & Psychology, UCLA
May 2006–Nov 2007.
Interdisciplinary study of socio-moral dysfunction in FTD. Ethnographic fieldwork in patients’ homes and care facilities, observations of diagnostic consensus meetings and interviews with patient family members.

Burning Man Census.
PIs: Megan Mullet & Kateri McRae.
Department of Anthropology, UCLA
Summer, 2007.
Technology consultant. Organized and implemented software and hardware for data acquisition (optical mark recognition) from thousands of surveys distributed at a large arts festival.

Vanishing Identities in Caribbean Performance Art.
PI: Dale Byam.
Interdisciplinary Arts and Performance, Arizona State University West
February, 1999.
Digital sound recording for a documentary of underground stick fighting in Trinidad.

Publications

S Torrisi, C Nord, N Balderston, J Roiser, C Grillon, M Ernst. Resting State Connectivity of the Human Habenula at Ultra-High Field. (submitted)

S Torrisi, K O’Connell, A Davis, R Reynolds, N Balderston, JL Fudge, C Grillon, M Ernst. (2015) Resting State Connectivity of the Bed Nucleus of the Stria Terminalis at Ultra-high Field. Human Brain Mapping, 36 4076–4088

S Torrisi, O Robinson, K O’Connell, A Davis, N Balderston, M Ernst, C Grillon. (2016) The Neural Basis of Improved Cognitive Performance by Threat of Shock. Social Cognitive and Affective Neuroscience, DOI: 10.1093/scan/nsw088

N Balderston, K Vytal, K O’Connell, S Torrisi, A Letkiewicz, M Ernst, C Grillon. (2016) Anxiety patients show reduced working memory related dlPFC activation during safety and threat. Depression and Anxiety, 1-12

M Ernst, S Torrisi, N Balderston, C Grillon, E Hale. FMRI functional connectivity applied to neurodevelopment, a focus on adolescence. Annu. Rev. Clin. Psychol. 2015. 11:6.1–6.17

K Cross, S Torrisi, ER Losin, M Iacoboni. (2013) Controlling automatic imitative tendencies: Interactions between mirror neuron and cognitive control systems. NeuroImage 83 493-504

S Torrisi, MD Lieberman, SY Bookheimer, LL Altshuler. (2013) Advancing understanding of affect labeling with dynamic causal modeling. NeuroImage 82, 481-488

S Torrisi, T Moody, M Thomason, N Vizueta, MM Monti, JD Townsend, J Fischer, SY Bookheimer, LL Altshuler. (2013) Differences in resting corticolimbic functional connectivity in bipolar I euthymia. Bipolar Disorders 15(2) 156-166.

JD Townsend, S Torrisi, MD Lieberman, CA Sugar, SY Bookheimer, LL Altshuler. (2013) Frontal-Amygdala Connectivity Alterations During Emotion Downregulation in Bipolar I Disorder. Biological Psychiatry, 73(2): 127-135.

N. Vizueta, JD. Rudie, JD. Townsend, S. Torrisi, TD. Moody, SY. Bookheimer, LL. Altshuler. (2012) Regional fMRI Hypoactivation and Altered Functional Connectivity During Emotion Processing in Nonmedicated Depressed Patients with Bipolar II Disorder. Am J Psychiatry. 2012; 169(8):831-40.

LC Foland-Ross, S. Bookheimer, MD Lieberman, J. Townsend, J. Fischer, S. Torrisi, C. Penfold, SK Madsen, PM Thompson, L. Altshuler. (2011) Normal amygdala activation but deficient ventrolateral prefrontal activation in adults with bipolar disorder during euthymia. NeuroImage. 2012; 59(1):738-44. Epub 2011 Aug 10.

I. Teramitsu, A. Poopatanapong, S. Torrisi, SA White. Striatal FoxP2 Is Actively Regulated during Songbird Sensorimotor Learning. PLoS One. January 2010; 5(1) e8548

Published Chapters

Ernst, M., Hale, L, Balderston, N., Torrisi, S (2015) Introduction to functional brain connectivity: potential contributions to understanding adolescent vulnerability to substance abuse. In S.F. Ewing, K Witkiewitz, F. Filbey (Eds.) Neuroimaging and Psychosocial Addiction Treatment. Palgrave Macmillan.

Torrisi, S. (2010). Social Regulation in Frontotemporal Dementia: A Case Study. In A. Mates, L. Mikesell, & M. Smith (Eds.) Language, Interaction and Frontotemporal Dementia: Reverse Engineering the Social Mind. London: Equinox Publishing

Conference Presentations

S. Torrisi, K O’Connell, A Gorka, A Davis, N Balderston, M Ernst, C Grillon. Voxel-wise Functional Connectivity of BNST and Central Amygdala Under Induced Anxiety. Presented at Anxiety and Depression Association of America. April 1-2, 2016, Philadelphia, PA.

S. Torrisi, O. Robinson, K O’Connell, A Davis, N Balderston, M Ernst, C Grillon. Neural Correlates of Response Inhibition Improved by Threat of Shock. Presented at the 21st annual meeting of the Organization of Human Brain Mapping. June 16, 2015, Honolulu, HI.

S. Torrisi, R. Reynolds, K O’Connell, A Davis, N Balderston, C Grillon, M Ernst. Resting connectivity of the Bed Nucleus of the Stria Terminalis. Presented at the 4th biennial Resting State Brain Connectivity Conference. Sept 13, 2014, Cambridge, MA.

S. Torrisi, K. McRae, N. Vizueta, S. Bookheimer, L.L. Altshuler. Hypoactivity in left vlPFC during reappraisal in bipolar disorder euthymia. Presented at the 19th annual meeting of the Organization of Human Brain Mapping. June 16-20, 2013, Seattle, WA.

S. Torrisi, N. Vizueta, J. Townsend, E. Lau, S. Bookheimer, L.L. Altshuler. Effective Connectivity Network Differences During Incidental Emotion Regulation in Euthymic Bipolar Disorder. Presented at the 67th Society of Biological Psychiatry annual meeting. May 3-5, 2012, Philadelphia, PA.

S. Torrisi, N. Vizueta, E. Berkman, L. Foland-Ross, J.D. Townsend, T.D. Moody, J. Fischer, S.Y. Bookheimer, L.L. Altshuler. Differences in Amygdala to VLPFC Resting State Functional Connectivity in Bipolar I Euthymia. Presented at the 17th Annual Organization for Human Brain Mapping meeting. June 26-30, 2011, Québec City, Canada.

S. Torrisi, J.D. Townsend, N. Vizueta, A. Aquino, J. Fischer, S.Y. Bookheimer, L.L. Altshuler Dysfunction of Frontal and Subcortical Connectivity During a Task of Emotion Regulation in Bipolar II Disorder Depression presented at New Horizons in Human Brain Imaging: A Focus on Brain Networks and Connectivity, December 1, 2010. Oahu, HI.

S. Torrisi, N. Vizueta, E. Berkman, L. Foland-Ross, J.D. Townsend, T.D. Moody, J. Fischer, S.Y. Bookheimer, L.L. Altshuler. Fronto-limbic Functional Connectivity in Bipolar II Depression during Emotion Labeling. Presented at the 4th Annual Meeting of the Social & Affective Neuroscience Society. September 18, 2010. Chicago, IL.

Music Publications

Torrisi, S. F0 r Woody, 2013 solo for clarinet and recording
Frog Peak Experimental Music Collective, Lebanon, NH

Torrisi, S. acute trio, 2004 computer-aided clarinet duet
Frog Peak Experimental Music Collective, Lebanon, NH

Academic Presentations

“Alterations In BNST Functional Connectivity During Induced Anxiety“ given in the symposium How the Human BNST and Amygdala Orchestrate Threat Processing at SOBP, May 14, 2016, Atlanta, GA.

“fMRI-based connectivity methods” Aug 21, 2015, at CSL, Georgetown University Medical Center.

“Resting connectivity of the BNST at ultra-high field” at fMRI/MRI seminar series, May 28, 2015, NIH.

Chair, mini-symposium “Human Subcortical Connectivity at High Field MRI” at SfN, Nov 19, 2014, DC.

Dissertation defense, July 9, 2013, UCLA.

Neuroscience Afterlab Research Forum, February 28, 2013, UCLA.

Presentation on FTD project to “Mind, Medicine and Culture” group, Dec 3rd 2007, UCLA.

Teaching Experience

Workshop on Dynamic Causal Modeling, UCLA, NITP Summer School
July 15, 2013

Teachers Assistant, UCLA, Dept. of Neuroscience; NS102 (Neuroanatomy)
Fall, 2012

Private instructor and counselor: Williams Syndrome Music Camp, Grand Rapids, MI
Summers, 2005 - 2009

Private clarinet instruction
1996 – 2005

General substitute teacher (grades 1-12) & music instructor (grade 4):
Vacaville Unified School District, Vacaville, CA
Sept 2004–June 2005

Lecturer, activities director and counselor:
Donner Mine Music Camp, Truckee, CA
Summers, 2000-2002

Professional Development

BNST masks made publically available (09.04.15):
http://afni.nimh.nih.gov/afni/community/board/read.php?1,149436,149436#msg-149436

Co-Coordinator of UCLA Neuroimaging + Journal Club
Winter, 2013

Principal clarinetist, Los Angeles Doctors Symphony Orchestra
2011 – 2012 season

Admissions committee, UCLA Neuroscience Interdepartmental Program
January – March. 2011

Admissions committee, CEAIT computer music festival
CalArts, Valencia, CA
Sept. 2002 – Jan. 2003

Awards

NIH Loan Repayment Program award 2016-2019

Fellowship to Summer Institute in Cognitive Neuroscience June 20-July 1, 2016, UCSB, CA

NIH Fellows Award for Research Excellence (FARE) 2016, travel award.

UCLA Neuroimaging Training Program Fellowship (NIH T90) Sept. 2011-Aug. 2012

New Horizons in Human Brain Imaging: Brain Networks and Connectivity Dec. 1-3, 2010 (Oahu, Hawaii)

Acceptance to NITP Advanced Neuroimaging Summer School, July 12-23, 2010. UCLA

UCLA QGE special course funding, spring & winter, 2010 (for two SPM courses in Boston)

UCLA QGE special course funding, spring, 2009 (for FSL/FreeSurfer course in San Francisco)

CalArts Scholarship, fall, 2003 (matched to L. May & R.V. Hagen)

Lulu May & Richard Von Hagen Scholarship, 2001 - 2002 (to top 5% incoming students)

Press

http://content.govdelivery.com/accounts/USNIMH/bulletins/122c889
http://dana.org/BrainWork/2013/When_Labeling_an_Emotion_Quiets_It/
http://blogs.plos.org/neuroanthropology/2010/10/14/frontotemporal-dementia-neuroanthropology-and-reverse-engineering-the-mind/

Workshop Participation

AFNI Bootcamp. December 2-6, 2013. National Institutes of Health, Bethesda.

SPM Course. February 15-17, 2012. University of Zurich, Switzerland.

Brain Connectivity Workshop. June 21-23, 2011. Université de Montréal. Montréal, Canada.

SPM8 for Basic and Clinical Investigators. Oct 11-15, 2010. A. A. Martinos Center, Charlestown, MA.

NITP Advanced Neuroimaging Summer School, July 12-23, 2010, UCLA.

SPM Network Analysis. March 15-17, 2010. Athinoula A. Martinos Center, Charlestown, MA.

FSL / FreeSurfer course. June 12-16, 2009. FMRIB Centre, MGH. Marriott Hotel, San Francisco, CA.