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Section on Neurobiology of Fear and Anxiety

Selected Publications

Gorka AX, Torrisi S, Shackman SJ, Grillon C, Ernst M. in press. Intrinsic functional connectivity of the central nucleus of the amygdala and bed nucleus of the stria terminalis. Neuroimage

Torrisi S, Gorka AX, Gonzalez-Castillo J, O’Connell K, Balderston N, et al. 2018. Extended amygdala connectivity changes during sustained shock anticipation. Translational Psychiatry 8: 33

Grillon C, Robinson OJ, O’Connell K, Davis A, Alvarez G, et al. 2017. Clinical anxiety promotes excessive response inhibition. Psychological Medicine 47: 484-94

Balderston NL, Hsiung A, Ernst M, Grillon C. 2017. The effect of threat on right dlPFC activity during behavioural pattern separation. J Neurosci 37: 9160-71

Balderston, NL, Liu, J, Roberson-Nay, R, Ernst, M, & Grillon, C (2017). The relationship between dlPFC activity during unpredictable threat and CO2-induced panic symptoms. Translational Psychiatry, 7(12), 1266.

Balderston NL, Hsiung A, Liu J, Ernst M, Grillon C (2017) Reducing State Anxiety Using Working Memory Maintenance. J Vis Exp:1–11.

Balderston NL, Hale E, Hsiung A, Torrisi S, Holroyd T, Carver FW, Coppola R, Ernst M, Grillon C (2017) Threat of shock increases excitability and connectivity of the intraparietal sulcus. Elife 6:1–27.

Cornwell BR, Garrido MI, Overstreet C, Pine DS, Grillon C. 2017. The un-predictive brain under threat: a neuro-computational account of anxious hypervigilance. Biol Psychiatry 82: 447-54

Grillon C, O’Connell K, Lieberman L, Alvarez G, Geraci M, et al. 2017. Distinct responses to predictable and unpredictable threat in anxiety pathologies: Effect of panic attack. Biol Psychiatry: CNNI 2: 575-81

Torrisi S, Nord CL, Balderston NL, Roiser JP, Grillon C, Ernst M. 2017. Resting state connectivity of the human habenula at ultra-high field. NeuroImage 147: 872-79

Lago T, Davis A, Grillon C, Ernst M. 2016. Striatum on the anxiety map; small detours into adolescence. Brain Research 1654: 177-84

Torrisi, S. J., Robinson, O., O'Connell, K., Davis, A., Balderston, N., Ernst, M., & Grillon, C. (2016). The neural basis of improved cognitive performance by threat of shock. Social Cognitive and Affective Neuroscience.

Balderston, N., Vytal, K. E., O'Connell, K., Torrisi, S. J., Letkiewicz, A., Ernst, M., et al. (2016). Anxiety Patients Show Reduced Working Memory Related DLPFC Activation During Safety and Threat. Depression and Anxiety, 1–12.

Ernst, M., Torrisi, S. J., Balderston, N., Grillon, C., & Hale, E. A. (2015). fMRI Functional Connectivity Applied to Adolescent Neurodevelopment*. Annual Review of Clinical Psychology, 11(1), 361–377. http://doi.org/10.1146/annurev-clinpsy-032814-112753

Torrisi, S. J., O'Connell, K., Davis, A., Reynolds, R., Balderston, N., Fudge, J. L., et al. (2015). Resting state connectivity of the bed nucleus of the stria terminalis at ultra-high field. Human Brain Mapping, 36(10), 4076–4088. http://doi.org/10.1002/hbm.22899

Vytal, K. E., Overstreet, C., Charney, D. R., Robinson, O. J., & Grillon, C. (2014). Sustained anxiety increases amygdala–dorsomedial prefrontal coupling: a mechanism for maintaining an anxious state in healthy adults. Journal of Psychiatry & Neuroscience: JPN, 39(4), 130145. http://doi.org/10.1503/jpn.130145

Robinson, O. J., Vytal, K. E., Cornwell, B. R., & Grillon, C. (2013). The impact of anxiety upon cognition: perspectives from human threat of shock studies. Frontiers in Human Neuroscience, 7, 1–21. http://journal.frontiersin.org/article/10.3389/fnhum.2013.00203/full

Schmitz, A., & Grillon, C. (2012). Assessing fear and anxiety in humans using the threat of predictable and unpredictable aversive events (the NPU-threat test). Nature Protocols, 7(3), 527–532. http://doi.org/10.1038/nprot.2012.001

Alvarez, R. P., Chen, G., Bodurka, J., Kaplan, R., & Grillon, C. (2011). Phasic and sustained fear in humans elicits distinct patterns of brain activity. NeuroImage, 55(1), 389–400. http://doi.org/10.1016/j.neuroimage.2010.11.057

Davis, M., Walker, D. L., Miles, L., & Grillon, C. (2010). Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety. Neuropsychopharmacology, 35(1), 105–135. http://doi.org/10.1038/npp.2009.109