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Benefits, Limitations, and Emerging Research Needs in Treating Youth with Depression » Meeting Agenda

Washington, DC

Day 1  
8:30 am Welcome and Introductions: Richard Nakamura, Ph.D.
Benedetto Vitiello, M.D. (NIMH)
8:45am What We Know About the Effects of Treatment Interventions
Chair: Benedetto Vitiello, M.D. (NIMH)


Presenter: Laura Mufson, Ph.D. (Columbia University)
Discussants: John Weisz, Ph.D. (Harvard Medical School)
Anne Simons, Ph.D. (University of Oregon)


Presenter: Graham Emslie, M.D. (Southwestern Medical
Discussants: Karen Wagner, M.D., Ph.D. (University of
Texas, Galveston)
Jörg Fegert, M.D. (University of Ulm)
10:30- 10:45 am Coffee break
10:45- 12:30 pm Combined Treatments

Presenters: John March, M.D. (Duke University)
Ian Goodyer, M.D. (Cambridge University)

Discussants: David Brent, M.D. (University of Pittsburgh)
Stanley Kutcher, M.D. (Dalhousie University)
12:30- 1:30 pm Lunch (on your own)
1:30- 2:45 pm How Do Treatments Work?
Chair: Joel Sherrill, Ph.D. (NIMH)

Understanding Mechanisms of Psychotherapy

Presenters: Robin Weersing, Ph.D. (Yale University)
Stephen Shirk, Ph.D. (University of Denver)

Searching for Biomarkers of Treatment Effects: Contributions from Neuroimaging

Presenter: David Rosenberg, M.D. (Wayne State University)
2:45-3:00 pm Coffee break
3:00-5:00 pm How to Individualize and Optimize Treatment
Chair: John Walkup, M.D. (Johns Hopkins University)

Panel: Joan Asarnow, Ph.D. (University of California, Los Angeles), Guillermo Bernal, Ph.D. (University of Puerto Rico), David Brent, M.D. (University of Pittsburgh), Gregory Clarke, Ph.D. (Kaiser Foundation), John Curry, Ph.D. (Duke University), Graham Emslie, M.D. (Southwestern Medical Center), Paul Rohde, Ph.D. (Oregon Research Institute), and Neal Ryan, M.D. (University of Pittsburgh)

For discussion:

How to address comorbidity (P. Rohde)
How to address non-response (D. Brent)
How to prevent relapse/recurrence (G. Emslie)
Cultural and ethnic issues (G. Bernal)
How effective are treatments in practice settings? (J. Asarnow & G. Clarke)
How to individualize treatment: possible predictors and moderators of response or adverse effects (J. Curry and N. Ryan)
Day 2 Approaching Future Research: Promises, Challenges, and Possible Solutions
8:30 am Treatment of Depression: Are We Always Using the Right Construct?

Speaker: Paul McHugh, M.D. (Johns Hopkins University)

9:45 am Coffee break
10:00 am Novel Approaches to Treatment Research
Chair: Shelli Avenevoli, Ph.D. (NIMH)

Panel: Joan Luby, M.D. (Washington University), John March, M.D. (Duke University), Kevin Stark, Ph.D. (University of Texas, Austin), Elizabeth McCauley, Ph.D. (University of Washington), and Mark Riddle, M.D. (Johns Hopkins University)

For discussion:

Treatment of prepubertal depression (K. Stark and J. Luby)
Clinical trials in practice settings: promise and challenges (J. March)
Testing treatment algorithms (M. Riddle)
Developing innovative treatment interventions (E. McCauley)
12 noon Summary and Conclusions
12:30 pm Adjourn