Research Highlights about Clinical Research and Trials
- New Approach Allows Magnetic Brain Stimulation to Target Deep Brain Structures
TMS can only directly stimulate the outermost layer of the brain, but NIMH researchers have found that mapping a person’s brain architecture may make it possible to guide TMS to deep brain targets.
- Improved Emotion Regulation in Dialectical Behavior Therapy Reduces Suicide Risk in Youth
An analysis of clinical trial data shows that improvements in emotion regulation in youth at high risk for suicide who received dialectical behavior therapy (DBT) led to a reduction in self-harm behaviors.
- NIMH Addresses Critical Need for Rapid-Acting Interventions for Severe Suicide Risk
NIMH is working to meet the urgent need for rapid-acting suicide prevention interventions by supporting research investigating the feasibility and safety of treatment protocols that have the potential to quickly reduce severe suicide risk in youth and adults.
- Using Mobile Technology to Improve Care for Teens with Depression
In a project funded by the NIMH Small Business Technology Transfer program, researchers are investigating whether mobile technology can be used to create a passive monitoring system that can predict teens’ depressive symptoms and improve the quality of their care.
- Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults
The use of right unilateral ultrabrief pulse (RUL-UB) electroconvulsive therapy (ECT) in combination with the antidepressant venlafaxine to treat depression in elderly patients is well tolerated and results in minimal neurocognitive side effects, according to a new NIH-funded study published in the American Journal of Geriatric Psychiatry.
- Transforming Mental Health Care Through ALACRITY
In 2018, 11.4 million adults in the United States experienced a serious mental illness, such as schizophrenia-spectrum disorders, severe bipolar disorder, and severe depression.