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Transforming the understanding
and treatment of mental illnesses.

Research Highlights about Clinical Research and Trials

Photo of the arms and hands of a female therapist holding the hands of a young woman.
Improved Emotion Regulation in Dialectical Behavior Therapy Reduces Suicide Risk in Youth

An analysis of clinical trial data shows that improvements in emotion regulation in youth at high risk for suicide who received dialectical behavior therapy (DBT) led to a reduction in self-harm behaviors.

National Institute of Mental Health
NIMH Addresses Critical Need for Rapid-Acting Interventions for Severe Suicide Risk

NIMH is working to meet the urgent need for rapid-acting suicide prevention interventions by supporting research investigating the feasibility and safety of treatment protocols that have the potential to quickly reduce severe suicide risk in youth and adults.

Using Mobile Technology to Improve Care for Teens with Depression
Using Mobile Technology to Improve Care for Teens with Depression

In a project funded by the NIMH Small Business Technology Transfer program, researchers are investigating whether mobile technology can be used to create a passive monitoring system that can predict teens’ depressive symptoms and improve the quality of their care.

Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults
Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults

The use of right unilateral ultrabrief pulse (RUL-UB) electroconvulsive therapy (ECT) in combination with the antidepressant venlafaxine to treat depression in elderly patients is well tolerated and results in minimal neurocognitive side effects, according to a new NIH-funded study published in the American Journal of Geriatric Psychiatry.

Transforming Mental Health Care Through ALACRITY
Transforming Mental Health Care Through ALACRITY

In 2018, 11.4 million adults in the United States experienced a serious mental illness, such as schizophrenia-spectrum disorders, severe bipolar disorder, and severe depression.