Research Highlights about Depression
- Mindful Mood Balance Effective for Treating Residual Depressive Symptoms and Suicidal Ideation
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NIMH-supported researchers have found an online mindfulness-based cognitive behavioral therapy—called Mindful Mood Balance—is effective at reducing residual depressive symptoms and at reducing suicidal ideation in those who experience these symptoms.
- New Approach Allows Magnetic Brain Stimulation to Target Deep Brain Structures
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TMS can only directly stimulate the outermost layer of the brain, but NIMH researchers have found that mapping a person’s brain architecture may make it possible to guide TMS to deep brain targets.
- Personalizing Deep Brain Stimulation for Treatment-Resistant Depression
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A recent NIMH-supported study investigated whether deep brain stimulation could be personalized for individuals with treatment-resistant depression.
- Assessing Suicide Risk Among Childbearing Women in the U.S. Before and After Giving Birth
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NIMH-supported researchers investigated suicide risk among women in the year before and year after giving birth.
- NIMH Addresses Critical Need for Rapid-Acting Interventions for Severe Suicide Risk
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NIMH is working to meet the urgent need for rapid-acting suicide prevention interventions by supporting research investigating the feasibility and safety of treatment protocols that have the potential to quickly reduce severe suicide risk in youth and adults.
- Using Mobile Technology to Improve Care for Teens with Depression
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In a project funded by the NIMH Small Business Technology Transfer program, researchers are investigating whether mobile technology can be used to create a passive monitoring system that can predict teens’ depressive symptoms and improve the quality of their care.
- Developing Rapid, Accurate Assessment of Mental Disorders, Suicide Risk in Youth
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For many adults who have a mental disorder, symptoms were present—but often not recognized or addressed—in childhood and adolescence. Early treatment can help prevent more severe, lasting impairment or disability as a child grows up.
- Combined Electroconvulsive Therapy and Venlafaxine a Well-Tolerated Depression Treatment for Older Adults
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The use of right unilateral ultrabrief pulse (RUL-UB) electroconvulsive therapy (ECT) in combination with the antidepressant venlafaxine to treat depression in elderly patients is well tolerated and results in minimal neurocognitive side effects, according to a new NIH-funded study published in the American Journal of Geriatric Psychiatry.