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Science News About HIV/AIDS

 A high-powered black and white microscope image showing exosomes, nanosized parts of cells. (Credit: Surya Shrivastava / City of Hope
Researchers Use Exosome-Based Strategy to Block HIV in Mice

In this NIMH-funded study, researchers used exosomes to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIV’s genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

Image showing HIV infection of CD4+ T cells in the mouse brain. Human T cells (magenta), human astrocytes (red), HIV (green), nuclei (Blue). Arrows identify uptake of HIV from astrocytes into T cells. Credit: Al-Harthi et al. (2020)
Brain Cells Can Harbor and Spread HIV Virus to the Body

Researchers funded by NIMH have found that astrocytes, a type of brain cell, can harbor HIV and then spread the virus to immune cells that traffic out of the brain and into other organs.

a male doctor faces the camera, listening to a male patient facing away from the camera
Novel Method Identifies Patients at Risk for HIV Who May Benefit From Prevention Strategies

Researchers have demonstrated the effectiveness of using algorithms that analyze electronic health records (EHRs) to help physicians identify patients at risk for HIV who may benefit from preexposure prophylaxis (PrEP), which significantly reduces the risk of getting HIV.

Man pressing the screen of a digital tablet
Targeted E-Health HIV Intervention Reduces STIs and Sexual Risk Behaviors

Findings from a new study suggest an electronically delivered HIV prevention intervention may be effective in reducing sexually transmitted infections (STIs) and sexual risk behaviors in young men who have sex with men.

An image showing the internal structure of the brain
Delay in HIV Treatment Associated with Brain Atrophy

People infected with the human immunodeficiency virus, known as HIV, display reductions in brain volume compared with people who are not infected with HIV, but now an NIMH-funded study has shed light on the course of this deterioration and shows that antiretroviral treatment started in the first few years of infection may stop these brain changes.

light brown mouse
Potential Source of HIV Persistence Confirmed

Scientists have shown that a class of immune cells not thought to be a primary reservoir for HIV can harbor the virus even following antiretroviral treatment (ART).