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Negative Valence Systems: Frustrative Nonreward - NIMH Research Domain Criteria (RDoC)

Domain: Negative Valence Systems
Construct: Frustrative Nonreward
————— Units of Analysis —————
Genes Molecules Cells Circuits Physiology Behavior Self-Reports Paradigms

MAOA, COMT, DAT1, 5HTTR, 5HTRs

Glutamate, Dopamine, Serotonin, GABA, Vasopressin, steroids

 

Septum, PAG, amygdala, hypothalamus, OFC, striatum, parasympathetic system, LC

 

physical and relational aggression

Proactive/ reactive aggression questionnaire, Buss-Durkee and Buss Perry

Physical and relational aggression paradigms, resident/human intruder test, PSAP, social dominance test