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A Study of Schizophrenia and the Brain: A Six-month Inpatient Evaluation Study

Join a Research Study: Enrolling nationally from around the country

To find out if you qualify, email NIMH or call 1-301-435-8970 (1-888-674-6464) [TTY: 1-866-411-1010].

The National Institute of Mental Health in Bethesda, Maryland, invites qualifying adults who have been diagnosed with schizophrenia or schizoaffective disorder to participate in an inpatient research study at the NIH Clinical Center. In this study, researchers will be evaluating how the brain works in individuals diagnosed with schizophrenia to better understand the underlying causes of this illness.

This study is usually six months long and generally has three phases: The first phase involves a thorough evaluation of diagnosis, medications, and treatment. The second phase includes evaluations during periods on and off standard medications, with each period ranging from four to six weeks. The third phase focuses on stabilization, treatment, and discharge planning.

Evaluations include a variety of medical, cognitive, neurological, and neurocognitive assessments. Advanced neuroimaging techniques (e.g., MRI, MEG, and PET) are used along with specialized cognitive tests designed to understand specific functions of the brain.