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Transforming the understanding
and treatment of mental illnesses.

How Cognitive Behavioral Therapy (CBT) May Change Stress Responses

Join a Research Study: Enrolling locally from the Washington, D.C. metro region

To find out if you qualify, email NIMH or call 1-301-451-7996 [TTY: 711].

This study seeks to understand how people who struggle with anxiety respond to different stressful situations, and how Cognitive Behavioral Therapy (CBT) may change these responses.

Research Participation Includes: Physical and neurological exams, EKG, blood and urine tests and stress-inducing tasks. Optional Cognitive Behavioral Therapy (CBT) is conducted over 8 outpatient group visits of 1.5 hours each.

Who Can Participate: The study is enrolling adults, aged 18-50, with generalized anxiety disorder, social anxiety disorder or a panic disorder. Eligibility includes fluency in English, in good health, free of certain medications and without recent drug or alcohol abuse (6 months).

Enrollees will participate in 2-4 outpatient procedural visits of 1.5 hours each and 8 CBT sessions. There is no cost to participate and compensation is provided. Research is conducted at the NIH Clinical Center, Bethesda, MD.

First Steps to Join a Study: Learn study details, be pre-screened for eligibility, and consent to participate. Refer to study 03-M-0093.

Study Identifiers

  • NIMH Protocol Number: 03-M-0093
  • ClinicalTrials.gov Study Number: 00055224

Investigator(s): Christian Grillon, Ph.D.