Skip to content

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC: https://www.coronavirus.gov
Get the latest research information from NIH: https://www.nih.gov/coronavirus

News and Multimedia Featuring IRP

Outdoor Light Linked with Teens’ Sleep and Mental Health

Press Release

A large-scale study of U.S. teens shows associations between outdoor, artificial light at night and health outcomes.

Read More

Infant Temperament Predicts Personality More Than 20 Years Later

Press Release

Researchers investigating how temperament shapes adult life-course outcomes have found that behavioral inhibition in infancy predicts a reserved, introverted personality at age 26 and for some, a risk of internalizing psychopathology such as anxiety and depression.

Read More

NIMH Scientific Director Susan Amara Selected as AAAS President-Elect

Institute Update

Susan Amara, Ph.D., scientific director of the Intramural Research Program at the National Institute of Mental Health (NIMH), has been selected to serve as president-elect of the American Association of the Advancement of Science (AAAS).

Read More

Side Effects Mild, Brief with Single Antidepressant Dose of Intravenous Ketamine

Press Release

A single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression.

Read More

Study Reveals Sex-Based Differences in the Development of Brain Hubs Involved in Memory and Emotion

Press Release

Researchers have uncovered sex-based differences in the development of the hippocampus and amygdala—brain areas that have been implicated in the biology of several mental disorders that impact males and females differently.

Read More

Release of “13 Reasons Why” Associated with Increase in Youth Suicide Rates

Press Release

A study conducted by researchers at several universities, hospitals, and the National Institute of Mental Health (NIMH) found that the Netflix show “13 Reasons Why” was associated with a 28.9% increase in suicide rates among U.S. youth ages 10-17 in the month (April 2017) following the shows release, after accounting for ongoing trends in suicide rates.

Read More

Bench-to-Bedside: NIMH Research Leading to Brexanolone, First-Ever Drug Specifically for Postpartum Depression

Media Advisory

FDA approval of the postpartum depression treatment brexanolone represents the final phase of a bench-to-bedside journey for this drug — a journey that began in the NIMH Intramural Research Program. NIMH experts are available to provide information on postpartum depression and the importance of, and the science underlying, this new drug.

Read More

NIH Study Reveals Differences in Brain Activity in Children with Anhedonia

Press Release

Researchers have identified changes in brain connectivity and brain activity during rest and reward anticipation in children with anhedonia, a condition where people lose interest and pleasure in activities they used to enjoy.

Read More

NIH Study Shows Many Preteens Screen Positive for Suicide Risk During ER Visits

Press Release

A research team found nearly one-third of youth ages 10 to 12 years screened positive for suicide risk in emergency department settings, including those seeking help for physical concerns only.

Read More

New Pathways for Implementing Universal Suicide Risk Screening in Healthcare Settings

Press Release

A new report provides guidance on how to implement universal suicide risk screening of youth in medical settings. The report describes a way for hospitals to address the rising suicide rate in a way that is flexible and mindful of limited resources.

Read More

Dynamic Associations Among Motor Activity, Sleep, Energy, and Mood Could Suggest New Focus for Depression Treatment

Science Update

A new study looking at interactions among sleep, energy, activity level, and mood suggests that instability in activity and sleep systems could lead to mood changes. The findings suggest new targets for depression treatment.

Read More

The Pathways Through which Light Affects Learning and Mood

Science Update

In a new study, researchers have traced the brain pathways responsible for the effects of light on learning and mood. The findings revealed that these effects are brought about by two different and distinct pathways from the retina into the brain.

Read More

Understanding the Brain Mechanisms of Irritability in Youth

Science Update

Researchers have identified differences in how the brains of irritable youth react to frustration, findings that could provide new paths for developing treatments for children and adolescents with severe irritability.

Read More

NIMH Director Joshua Gordon and IRP Researcher Ellen Leibenluft Elected to the National Academy of Medicine

Institute Update

Joshua A. Gordon, M.D., Ph.D., director of the National Institute of Mental Health (NIMH), and Ellen Leibenluft, M.D., chief of the Section on Mood Dysregulation and Neuroscience and co-chief of the Emotion and Development Branch in the NIMH Intramural Research Programs, have been elected as members of the National Academy of Medicine.

Read More

“Covert” Neurofeedback Tunes-up the Social Brain in ASD

Science Update

Young people with autism unknowingly tuned up flagging neural connections by playing a picture puzzle game that was rigged by their own brain activity.

Read More

Understanding Critical Components of the Brain’s Stress Circuitry

Science Update

A new study has revealed more about the organization and function of a brain structure—the paraventricular nucleus of the thalamus—that may serve a key role in linking stress detection to the development of adaptive behaviors.

Read More

Bigger Human Brain Prioritizes Thinking Hub – at a Cost

Press Release

Scientists have discovered that bigger human brains are organized differently than smaller ones.

Read More

Age-Related Racial Disparity in Suicide Rates Among U.S. Youth

Press Release

Researchers have discovered an age-related racial disparity in suicide rates for U.S. youth between the ages of 5 and 17. The findings suggest a need for more research into contributing factors and targeted interventions for children.

Read More

NIMH to Host Twitter Chat on Teen Depression

Institute Update

On May 3, 2018, join NIMH for a Twitter chat on teen depression with experts Dr. Argyris Stringaris and Dr. Ken Towbin.

Read More

Intramural Researchers Develop Suicide Risk Screening Toolkit for Medical Settings

Science Update

NIMH researchers have developed a brief screening questionnaire for medical professionals to identify youth at risk for suicide.

Read More

Our Brains Harbor “Residual Echo” of Neanderthal Genes

Science Update

Researchers have produced the first direct evidence that parts of our brains implicated in mental disorders may be shaped by a “residual echo” from our ancient past. The more a person’s genome carries genetic vestiges of Neanderthals, the more certain parts of his or her brain and skull resemble those of humans’ evolutionary cousins that went extinct 40,000 years ago.

Read More

Guidelines published for treating PANS/PANDAS

Science Update

An expert panel has published guidelines for treatment of Pediatric Acute Onset Neuropsychiatric Syndrome (PANS) and a subset of patients diagnosed with PAN Disorder Associated with Streptococcal Infection (PANDAS).

Read More

NIMH to Host Multimodal Brain Stimulation Speaker Series

Science Update

Beginning May 31, 2017, the National Institute of Mental Health (NIMH) will launch a speaker series intended to bring together leaders in the field conducting research using non-invasive brain stimulation and functional imaging including EEG, fMRI, and transcranial magnetic stimulation (TMS).

Read More

Brain “Relay” Also Key to Holding Thoughts in Mind

Press Release

Long overlooked as a mere “relay,” an egg-like structure in the middle of the brain also turns out to play a pivotal role in tuning-up thinking circuity. A trio of studies in mice are revealing that the thalamus sustains the ability to distinguish categories and hold thoughts in mind. It might even become a target for interventions for psychiatric disorders marked by working memory problems, such as schizophrenia.

Read More

Emergency Departments Could Play Significant Role in Reducing Suicide Attempts

Science Update

Research funded by the National Institute of Mental Health (NIMH) shows hospital emergency departments can play a vital role in lowering the number of suicide attempts among adults by as much as 30 percent.

Read More

Estrogen Alters Memory Circuit Function in Women with Gene Variant

Science Update

Brain scans reveal that fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene. Since working memory function is often disturbed in mental disorders, such gene-hormone interactions are suspect mechanisms that may confer risk.

Read More

Sex Hormone–Sensitive Gene Complex Linked to Premenstrual Mood Disorder

Press Release

Researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

Read More

NIMH’s Francis McMahon, M.D., Awarded Prestigious Colvin Prize

Science Update

The National Institute of Mental Health (NIMH) announces that Francis McMahon, M.D., is a recipient of the Brain & Behavior Research Foundation’s 2016 Colvin Prize for Outstanding Achievement in Mood Disorders Research.

Read More

Circuitry for Fearful Feelings, Behavior Untangled in Anxiety Disorders

Science Update

Untangling the brain circuitry of fearful feelings from that underlying defensive behaviors is key to improving treatments for anxiety disorders, argue two leading experts.

Read More

Game Corrects Children’s Misreading of Emotional Faces to Tame Irritability

Science Update

A computer game that changes a tendency to misread ambiguous faces as angry is showing promise as a potential treatment for irritability in children

Read More

Ketamine Lifts Depression via a Byproduct of its Metabolism

Press Release

A chemical byproduct, or metabolite, created as the body breaks down likely holds the secret to its rapid antidepressant action .

Read More

Secrets to Our Smarts Hidden in the Folds of Our Cortex

Science Update

The more folding in the thinking parts of our brain, the smarter we are – to a degree.

Read More

Circuit Tweak Boosts Social Memory in Mice

Science Update

Researchers have boosted the staying power of a social memory at least 80-fold by stimulating a circuit they discovered in mouse brain.

Read More