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All News and Multimedia Featuring IRP

screenshot from video Discover NIMH: Drug Discovery and Development
Discover NIMH: Drug Discovery and Development

One of the most exciting recent breakthroughs from research funded by the National Institute of Mental Health (NIMH) is the development of a fast-acting medication for treatment-resistant depression based on ketamine. This treatment is bringing new hope to people and families affected by major depression.

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Study Reveals Sex-Based Differences in the Development of Brain Hubs Involved in Memory and Emotion

Press Release

Researchers have uncovered sex-based differences in the development of the hippocampus and amygdala—brain areas that have been implicated in the biology of several mental disorders that impact males and females differently.

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National Institute of Mental Health
Elisa Dumett, Ph.D., Winner of the 2018 NIMH Three-Minute Talks Competition

Elisa Dumett Torres, Ph.D., winner of the 2018 NIMH Three-Minute Talks Competition, presents her three minute talk on viewing hippocampal functional coupling through the lens of environmental factor of urbanicity and the genetic factor BDNF. Her study provides a template for exploring the effects of gene environment interactions for general brain function and how this might be altered in psychiatric illness.

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National Institute of Mental Health
Laura Padilla, Ph.D., Winner of the 2018 NIMH Three-Minute Talks Competition

Laura Padilla, Ph.D., winner of the 2018 NIMH Three-Minute Talks Competition, presents her three minute talk on reward related functional connectivity wth nucleus accumbens changes across puberty. Her study will attempt to disentangle the roles of age, puberty stage, and hormonal events of puberty in the development of reward processing.

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illustration of human brain in blue
Dr. Niko Kriegeskorte: How can computer models help us better understand the brain?

Dr. Niko Kriegeskorte, a computational neuroscientist from the Zuckerman Institute at Columbia University, discusses the challenges of deriving insight into the principles of brain function using fMRI and other neuroimaging methods.

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teen boy smiles at doctor
Webinar for Nurses - How to Use the ASQ to Detect Patients at Risk for Suicide

In this webinar, Dr. Lisa Horowitz reviews how to conducts suicide risk screening with the ASQ tool. This training is for nurses.

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screenshot from NIMH viddeo Suicide Risk Screening Training: How to Manage Patients at Risk for Suicide
Suicide Risk Screening Training: How to Manage Patients at Risk for Suicide

Suicide Risk Screening Training for Mental Health Clinicians: How to Manage Patients at Risk for Suicide by Lisa M. Horowitz, Ph.D., MPH, Office of the Clinical Director, Intramural Research Program, National Institute of Mental Health

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Release of “13 Reasons Why” Associated with Increase in Youth Suicide Rates

Press Release

A study conducted by researchers at several universities, hospitals, and the National Institute of Mental Health (NIMH) found that the Netflix show “13 Reasons Why” was associated with a 28.9% increase in suicide rates among U.S. youth ages 10-17 in the month (April 2017) following the shows release, after accounting for ongoing trends in suicide rates.

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illustration of human brain in blue
Autism in Adults

Over the last twenty years, research has helped us better understand autism in adults. In a podcast, NIMH Director Dr. Joshua Gordon interviews Dr. Ann Wagner, National Autism Coordinator, and Dr. Lisa Gilotty, chief of NIMH’s Research Program on Autism Spectrum Disorders, to discuss these research advances.

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Bench-to-Bedside: NIMH Research Leading to Brexanolone, First-Ever Drug Specifically for Postpartum Depression

Press Release

FDA approval of the postpartum depression treatment brexanolone represents the final phase of a bench-to-bedside journey for this drug — a journey that began in the NIMH Intramural Research Program. NIMH experts are available to provide information on postpartum depression and the importance of, and the science underlying, this new drug.

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NIH Study Reveals Differences in Brain Activity in Children with Anhedonia

Press Release

Researchers have identified changes in brain connectivity and brain activity during rest and reward anticipation in children with anhedonia, a condition where people lose interest and pleasure in activities they used to enjoy.

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NIH Study Shows Many Preteens Screen Positive for Suicide Risk During ER Visits

Press Release

A research team found nearly one-third of youth ages 10 to 12 years screened positive for suicide risk in emergency department settings, including those seeking help for physical concerns only.

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screenshot from NIMH video Putting behavior into context: how neuromodulators and flies can help
Putting behavior into context: how neuromodulators and flies can help

This is a cat video unlike any other you’ve seen. This video is about a completely ordinary cat that led to extraordinary places –and may even lead to answers about mental illnesses. We don’t know yet. But this cat’s story is definitely about discovery and purpose and meaning.

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screenshot form NIMH video Teen Depression Study
Teen Depression Study - 3

NIMH conducts research studies to understand the causes of depression, the teen brain, and evaluate new treatments. Studies enroll participants, ages 11-17.

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screenshot form NIMH video Teen Depression Study
Teen Depression Study - 1

NIMH conducts research studies to understand the causes of depression, the teen brain, and evaluate new treatments. Studies enroll participants, ages 11-17, for research assessments, brain scans, talk therapy or other standard treatments.

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screenshot from NIMH video Teen Depression Study
Teen Depression Study - 2

NIMH conducts research studies to understand the causes of depression, the teen brain, and evaluate new treatments. Studies enroll participants, ages 11-17.

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screenshot from NIMH video Social Anxiety Disorder - Join A Study
Social Anxiety Disorder - Join A Study

People with social anxiety disorder have a general intense fear of, or anxiety toward, social or performance situations.

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screenshot from NIMH video Join a Research Study
Join a Research Study

Researchers at the National Institute of Mental Health (NIMH) conduct a large number of research studies with patients and healthy volunteers.

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screenshot from NIMH video Join a Study
Join a Research Study

Researchers at the National Institute of Mental Health (NIMH) conduct a large number of research studies with patients and healthy volunteers.

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screenshot from NIMH video Generalized and Social Anxiety Disorders
Generalized and Social Anxiety Disorders - Join A Study

People with generalized anxiety disorder (GAD) display excessive anxiety or worry, most days for at least 6 months, about a number of things such as personal health, work, social interactions, and everyday routine life circumstances.

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illustration of human brain in blue
Francisco Pereira, Ph.D.: How can machine learning help brain imaging?

NIMH’s Dr. Peter Bandettini interviews Dr. Francisco Pereira about how researchers might address challenges in neuroscience using machine learning approaches.

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illustration of human brain in blue
Danny Pine, M.D.: Can clinical fMRI research transfer to the clinic?

For 25 years, functional magnetic resonance imaging or functional MRI (fMRI) has generated excitement in the research community and public, shedding insight into systems level organization of the brain in healthy and clinical population. But can fMRI provide actionable information or have a meaningful impact on clinical practice? NIMH’s Dr. Peter Bandettini talks with NIIMH IRP psychiatrist and fMRI researcher, Dr. Danny Pine, about how and when fMRI might ‘go clinical.’

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video screenshot from Discover NIMH: Intramural Research Program Training
Discover NIMH: Intramural Research Program Training

NIMH’s Intramural Research Program offers training opportunities and resources meant to develop a diverse, highly qualified workforce.

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New Pathways for Implementing Universal Suicide Risk Screening in Healthcare Settings

Press Release

A new report provides guidance on how to implement universal suicide risk screening of youth in medical settings. The report describes a way for hospitals to address the rising suicide rate in a way that is flexible and mindful of limited resources.

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Dynamic Associations Among Motor Activity, Sleep, Energy, and Mood Could Suggest New Focus for Depression Treatment

Science Update

A new study looking at interactions among sleep, energy, activity level, and mood suggests that instability in activity and sleep systems could lead to mood changes. The findings suggest new targets for depression treatment.

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screenshot from adolescent depression webinar
Behavioral Activation: Treatment of Adolescent Depression

Clinical Psychologist Dr. Kathryn DeLonga of the NIMH Mood Brain and Development Unit discusses treating depressed teens with a talk therapy called Behavioral Activation.

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video screenshot of Frances Johnson, NIMH trainee
One Trainee’s Story

Frances Johnson talks about her experiences as a recipient of a NIMH Diversity Supplement grant and her summer stint in an NIMH intramural lab under NIH’s G-SOAR Program.

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video screenshot of Frances Johnson, NIMH trainee
Frances’ Advice to Students

NIMH trainee Frances Johnson offers advice to students interested in scientific research.

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The Pathways Through which Light Affects Learning and Mood

Science Update

In a new study, researchers have traced the brain pathways responsible for the effects of light on learning and mood. The findings revealed that these effects are brought about by two different and distinct pathways from the retina into the brain.

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Video.
UCL-NIMH Joint Doctoral Program in Neuroscience

Jobert Vargas, BS, talks about his experience in the UCL-NIMH Joint Doctoral Program in Neuroscience.

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Office of Training and Fellowship video
KI-NIH Collaborative Doctoral Program in Neuroscience

Stal Shrestha, PhD talks about his experience in the KI-NIH Collaborative Doctoral Program in Neuroscience.

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Video.
PGY4 Residency Training and Clinical Fellowship Program & NIMH

Gioia Guerrieri DO, FAPA, talks about her experience in the PGY4 Residency Training and Clinical Fellowship Program & NIMH

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Office of Training and Fellowship video
Clinical Fellowship Program at NIMH

Mark Niciu, MD, PhD, talks about his experience in the Clinical Fellowship Program at NIMH.

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Understanding the Brain Mechanisms of Irritability in Youth

Science Update

Researchers have identified differences in how the brains of irritable youth react to frustration, findings that could provide new paths for developing treatments for children and adolescents with severe irritability.

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NIMH Director Joshua Gordon and IRP Researcher Ellen Leibenluft Elected to the National Academy of Medicine

Institute Update

Joshua A. Gordon, M.D., Ph.D., director of the National Institute of Mental Health (NIMH), and Ellen Leibenluft, M.D., chief of the Section on Mood Dysregulation and Neuroscience and co-chief of the Emotion and Development Branch in the NIMH Intramural Research Programs, have been elected as members of the National Academy of Medicine.

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“Covert” Neurofeedback Tunes-up the Social Brain in ASD

Science Update

Young people with autism unknowingly tuned up flagging neural connections by playing a picture puzzle game that was rigged by their own brain activity.

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neuro feedback video screenshot
“Covert” Neurofeedback Tweaks Brain in ASD

Young people with autism unknowingly tuned up flagging neural connections by playing a picture puzzle game that was rigged by their own brain activity.

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Understanding Critical Components of the Brain’s Stress Circuitry

Science Update

A new study has revealed more about the organization and function of a brain structure—the paraventricular nucleus of the thalamus—that may serve a key role in linking stress detection to the development of adaptive behaviors.

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Bigger Human Brain Prioritizes Thinking Hub – at a Cost

Press Release

Scientists have discovered that bigger human brains are organized differently than smaller ones.

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Age-Related Racial Disparity in Suicide Rates Among U.S. Youth

Press Release

Researchers have discovered an age-related racial disparity in suicide rates for U.S. youth between the ages of 5 and 17. The findings suggest a need for more research into contributing factors and targeted interventions for children.

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NIMH to Host Twitter Chat on Teen Depression

Institute Update

On May 3, 2018, join NIMH for a Twitter chat on teen depression with experts Dr. Argyris Stringaris and Dr. Ken Towbin.

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Intramural Researchers Develop Suicide Risk Screening Toolkit for Medical Settings

Science Update

NIMH researchers have developed a brief screening questionnaire for medical professionals to identify youth at risk for suicide.

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Video.
Ashley Smith, Ph.D., Winner of the 2017 NIMH Three-Minute Talks Competition

Ashley Smith, Ph.D., winner of the 2017 NIMH Three-Minute Talks Competition, presents her three minute talk on social anxiety in adolescents.

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Video.
Katherine Reding, Ph.D., Winner of the 2017 NIMH Three-Minute Talks Competition

Katherine Reding, Ph.D., winner of the 2017 NIMH Three-Minute Talks Competition, presents her three minute talk on puberty and psychopathology in teen girls.

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Video.
Lora D. Weidner, Ph.D., Winner of the 2017 NIMH Three-Minute Talks Competition

Lora D Weidner, Ph.D., winner of the 2017 NIMH Three-Minute Talks Competition, presents her three minute talk on finding which brain cells express COX-1 and COX-2 enzymes, and how to potentially reduce brain inflammation in diseases such as epilepsy and Alzheimer’s.

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Our Brains Harbor “Residual Echo” of Neanderthal Genes

Science Update

Researchers have produced the first direct evidence that parts of our brains implicated in mental disorders may be shaped by a “residual echo” from our ancient past. The more a person’s genome carries genetic vestiges of Neanderthals, the more certain parts of his or her brain and skull resemble those of humans’ evolutionary cousins that went extinct 40,000 years ago.

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Guidelines published for treating PANS/PANDAS

Science Update

An expert panel has published guidelines for treatment of Pediatric Acute Onset Neuropsychiatric Syndrome (PANS) and a subset of patients diagnosed with PAN Disorder Associated with Streptococcal Infection (PANDAS).

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NIMH to Host Multimodal Brain Stimulation Speaker Series

Science Update

Beginning May 31, 2017, the National Institute of Mental Health (NIMH) will launch a speaker series intended to bring together leaders in the field conducting research using non-invasive brain stimulation and functional imaging including EEG, fMRI, and transcranial magnetic stimulation (TMS).

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Brain “Relay” Also Key to Holding Thoughts in Mind

Press Release

Long overlooked as a mere “relay,” an egg-like structure in the middle of the brain also turns out to play a pivotal role in tuning-up thinking circuity. A trio of studies in mice are revealing that the thalamus sustains the ability to distinguish categories and hold thoughts in mind. It might even become a target for interventions for psychiatric disorders marked by working memory problems, such as schizophrenia.

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Emergency Departments Could Play Significant Role in Reducing Suicide Attempts

Science Update

Research funded by the National Institute of Mental Health (NIMH) shows hospital emergency departments can play a vital role in lowering the number of suicide attempts among adults by as much as 30 percent.

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Estrogen Alters Memory Circuit Function in Women with Gene Variant

Science Update

Brain scans reveal that fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene. Since working memory function is often disturbed in mental disorders, such gene-hormone interactions are suspect mechanisms that may confer risk.

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Sex Hormone–Sensitive Gene Complex Linked to Premenstrual Mood Disorder

Press Release

Researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

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NIMH’s Francis McMahon, M.D., Awarded Prestigious Colvin Prize

Science Update

The National Institute of Mental Health (NIMH) announces that Francis McMahon, M.D., is a recipient of the Brain & Behavior Research Foundation’s 2016 Colvin Prize for Outstanding Achievement in Mood Disorders Research.

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Circuitry for Fearful Feelings, Behavior Untangled in Anxiety Disorders

Science Update

Untangling the brain circuitry of fearful feelings from that underlying defensive behaviors is key to improving treatments for anxiety disorders, argue two leading experts.

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Game Corrects Children’s Misreading of Emotional Faces to Tame Irritability

Science Update

A computer game that changes a tendency to misread ambiguous faces as angry is showing promise as a potential treatment for irritability in children

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Video.
Irritability in Children - Disruptive Mood Dysregulation Disorder

Ellen Leibenluft, M.D., NIMH Emotion and Development Branch, explains the history of Disruptive Mood Dysregulation Disorder.

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Video.
Irritability in Children - Facial Emotion Study

Drs Ellen Leibenluft and Melissa Brotman, NIMH Emotion and Development Branch, explain a study aimed at reducing irritability in children by re-training their responses to facial emotion.

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Video.
Irritability in Children - How Parents Can Help

Dr. Ellen Leibenluft, NIMH Emotion and Development Branch, discusses how parents can help an irritable child.

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Video.
Irritability in Children - Dr. Ellen Leibenluft

Dr. Ellen Leibenluft, NIMH Emotion and Development Branch, discusses research on irritability in children.

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Video.
Webinar: Severe Irritability and DMDD in Youth -- Dr. Kenneth Towbin

NIMH child and adolescent psychiatrist Kenneth Towbin, M.D., discusses NIMH research into childhood severe irritability and disruptive mood dysregulation.

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Ketamine Lifts Depression via a Byproduct of its Metabolism

Press Release

A chemical byproduct, or metabolite, created as the body breaks down likely holds the secret to its rapid antidepressant action .

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Secrets to Our Smarts Hidden in the Folds of Our Cortex

Science Update

The more folding in the thinking parts of our brain, the smarter we are – to a degree.

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Circuit Tweak Boosts Social Memory in Mice

Science Update

Researchers have boosted the staying power of a social memory at least 80-fold by stimulating a circuit they discovered in mouse brain.

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NIMH Twitter Chat on Clinical Research Participation

Live Chat

NIMH Twitter Chat on Men and Depression

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Rapid Agent Restores Pleasure-seeking Ahead of Other Antidepressant Action

Press Release

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior independent of – and ahead of – its other antidepressant effects.

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NIMH Twitter Chat on Depression and the Development of Novel Medications

Science Update

NIMH Twitter Chat on Depression and the Development of Novel Medications

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Unearthing Secrets of New Neurons
Unearthing Secrets of New Neurons

Unearthing Secrets of New Neurons

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NIMH Twitter Chat on Premenstrual Dysphoric Disorder

Science Update

NIMH Twitter Chat on Premenstrual Dysphoric Disorder

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Common Gene Variants Account for Most Genetic Risk for Autism

Press Release

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

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Genes Impact Suspect Cortex Areas More as Youth Mature

Science Update

Later evolving and maturing brain areas, which also are those most implicated in mental illness, showed gradually increasing heritability, peaking by late adolescence – the age-of-onset for most mental disorders. New findings hold promise for understanding how age plays an important role in gene-environment interactions that underlie the disorders.

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Genes Impact Suspect Cortex Areas More as Youth Mature
Genes Impact Suspect Cortex Areas More as Youth Mature

Genes Impact Suspect Cortex Areas More as Youth Mature

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NIMH Twitter Chat on Postpartum Depression

Science Update

NIMH Twitter Chat on Postpartum Depression

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Channel Makeover Switches Off Neurons in a Flash
Channel Makover Switches Off Neurons in a Flash

Channel Makover Switches Off Neurons in a Flash

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NIMH Twitter Chat on Autism Spectrum Disorder Diagnosis

Science Update

NIMH Twitter Chat on Autism Spectrum Disorder Diagnosis

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Video.
Patches of Disorganization in the Neocortex of Children with Autism

Patches of Disorganization in the Neocortex of Children with Autism

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Video.
Middle Schoolers’ Field Day with the Brain

Middle Schoolers’ Field Day with the Brain

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Suicide in the Military: Army-NIH Funded Study Points to Risk and Protective Factors

Press Release

Although the suicide attempt and death rates in the U.S. Army have been historically below the civilian rate, these rates began climbing in the early 2000s, and by 2008, exceeded those of civilians. A joint study between the Army and NIMH, called Army STARRS, recently released findings that shed light on the problem.

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Video.
Eating Disorders Myths Busted - Myth #1: You can tell by looking at someone

Eating Disorders Myths Busted - Myth #1: You can tell by looking at someone

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Video.
Eating Disorders Myths Busted - Myth #2: Families are to Blame

Eating Disorders Myths Busted - Myth #2: Families are to Blame

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Video.
Eating Disorders Myths Busted - Myth #3: Mothers are to Blame

Eating Disorders Myths Busted - Myth #3: Mothers are to Blame

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Video.
Eating Disorders Myths Busted - Myth #4: Eating Disorders are a Choice

Eating Disorders Myths Busted - Myth #4: Eating Disorders are a Choice

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Video.
Eating Disorders Myths Busted - Myth #5: Eating Disorders are the province of white upper-middle class teenage girls

Eating Disorders Myths Busted - Myth #5: Eating Disorders are the province of white upper-middle class teenage girls

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Video.
Eating Disorders Myths Busted - Myth #6: Eating Disorders are Benign

Eating Disorders Myths Busted - Myth #6: Eating Disorders are Benign

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Video.
Eating Disorders Myths Busted - Myth #7: Society Alone to Blame

Eating Disorders Myths Busted - Myth #7: Society Alone to Blame

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Video.
Eating Disorders Myths Busted - Myth #8: Genes are Destiny

Eating Disorders Myths Busted - Myth #8: Genes are Destiny

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Video.
Eating Disorders Myths Busted - Myth #9: Eating Disorders are for Life

Eating Disorders Myths Busted - Myth #9: Eating Disorders are for Life

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NIMH Twitter Chat on Eating Disorders

Science Update

NIMH Twitter Chat on Eating Disorders

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NICHD/NIMH Podcast on Youth Violence

Science Update

NIMH/NICHD experts explain what sparks and halts youth violence.

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Video.
Bullying Exerts Psychiatric Effects Into Adulthood

Once considered a childhood rite of passage, bullying lingers well into adulthood. Bullies and victims alike are at risk for psychiatric problems such as anxiety, depression, substance abuse, and suicide when they become adults, reported a study partially funded by the National Institute of Mental Health (NIMH) that was published in the April issue of JAMA Psychiatry.

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Video.
Project Achieve Weight Loss Trial for People with Serious Mental Illness

NIMH grantee Dr. Gail Daumit talks about the Project Achieve weight loss trial.

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Video.
NIMH’s Dr. Maura Furey on scopolamine research

Dr. Maura Furey on the search for a fast acting anti-depressant.

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