Haller, S.P.*, Linke, J.O., Grassie, H.*, Jones, E., Pagliaccio, D., Harrewijn, A., White, L., Naim, R.*, Mallidi, A., Berman, E., Lewis, K., Kircanski, K., Silverman, W.K., Kalin, N., Bar-Haim, Y., Brotman, M.A. (2024). Cognitive behavioral therapy normalizes fronto-parietal activation in unmedicated patients with pediatric anxiety disorders. American Journal of Psychiatry. [Epub ahead of print]

Brotman, M.A., Haller, S.P., Pine, D.S., Fox, N.A. (in press). From Deconstruction to Reconstruction: A search for natural kinds in developmental psychopathology. Journal of Psychopathology and Clinical Science.

Henry, L.M.*, Pandya, U.*, Malone, E., Miller, C., Agyemang, S., Tandilashvili, E.*, Lewis, K.*, Haeffner, C., Lee, K., Livinski, A., Kiderman, M.*, Naim, R.*, Metcalf, O., Lopez-Guzman, S., Brotman, M.A. (in press). Adherence with ecological momentary assessment studies in children and adolescents with psychopathology: A protocol for a systematic review and meta-analysis. Neuropsychopharmacology Digital Psychiatry and Neuroscience.

Naim, R.*, Dombek, K.*, German, R.E.*, Haller, S.P.*, Kircanski, K., Brotman, M.A. (2023). An exposure-based cognitive-behavioral therapy for youth with severe irritability: Feasibility and preliminary efficacy. Journal of Clinical Child and Adolescent Psychology [Epub ahead of print]

Henry, L.M.*, Hansen, E.*, Chimoff, J., Pokstis, K., Kiderman, M., Naim, R.*, Kossowsky, J., Lopez-Guzman, S., Kircanski, K., Pine, D.S., Brotman, M.A. (2024). Selecting an Ecological Momentary Assessment Platform: Tutorial for researchers. Journal of Medical Internet Research, 26(1), e51125.

Grasser, L.,R.*, Erjo, T.*, Goodwin, M.S., Naim, R.*, German, R.E., White, J., Cullins, L., Tseng, W.-L., Stoddard, J., Brotman, M.A. (2023). Can peripheral psychophysiological markers predict response to exposure-based cognitive behavioral therapy in youth with severely impairing irritability: A study protocol. BMC Psychiatry, 23(1), 926.

Tseng, W.-L., Naim, R.*, Chue, A., Shaughnessy, S.*, Pine, D.S., Leibenluft, E., Brotman, M.A. (2023). Network analysis of ecological momentary assessment identifies frustration as a central node in irritability. Journal of Child Psychology and Psychiatry, 64(8), 1212-1221.

Aggarwal, N., Oler, J., Brotman, M.A., Kalin, N. (2024). A preliminary study of the effects of an antimuscarinic agent on anxious behaviors and white matter microarchitecture in nonhuman primates. Neuropsychopharmacology, 349(2), 405-413. https://www.nature.com/articles/s41386-023-01686-1 

Naim, R., Haller, S., Jaffe, A., Linke, J., Kircanski, K., Stoddard, J., Brotman, M.A. (2022). Context-dependent amygdala-prefrontal connectivity during the dot-probe task varies by irritability and attention bias to angry faces. Neuropsychopharmacology. Context-dependent amygdala–prefrontal connectivity during the dot-probe task varies by irritability and attention bias to angry faces https://www.nature.com/articles/s41386-022-01307-3 

Brotman, M.A. & Kircanski, K. (2022). A Cry for Help: We need nonpharmacological randomized controlled trials for pediatric irritability. Journal of the American Academy of Child and Adolescent Psychiatry https://www.sciencedirect.com/science/article/pii/S0890856722003665?via%3Dihub 

Naim, R., Shaughnessy, S., Smith, A., Karalunas, S., Kircanski, K., Brotman, M.A. (2023). Real-time assessment of positive and negative affective fluctuations and mood lability in a transdiagnostic sample of youth. Depression and Anxiety https://onlinelibrary.wiley.com/doi/pdf/10.1002/da.23293 

Wilson, M., Cornacchio, D., Brotman, M.A., Comer, J.S. (2022). Measuring irritability in early childhood: A psychometric evaluation of the Affective Reactivity Index in a clinical sample of 3- to 8-year-old children. Assessment. https://journals.sagepub.com/doi/pdf/10.1177/10731911211020078 

Haller, S., Archer, C., Jeong, A., Jaffe, A., Jones, E.L., Harrewijn, A., Naim, R., Linke, J.O., Stoddard, J., Brotman, M.A. (2022). Changes in internalizing symptoms during the COVID-19 pandemic in a transdiagnostic sample of youth: Exploring mediators and predictors Child Psychiatry & Human Development. https://link.springer.com/article/10.1007/s10578-022-01382-z 

Smith, A.R., Jones, E.L., Subar, A.R., Do, Q.B., Kircanski, K., Brotman, M.A., Pine, D.S., Silk, J.S. (2022). The role of anxiety and gender in anticipation and avoidance of naturalistic anxiety-provoking experiences during adolescence: An ecological momentary assessment study. Journal of Clinical Psychology and Psychiatry Advances. https://acamh.onlinelibrary.wiley.com/doi/full/10.1002/jcv2.12084 

Vogel-Hammen, A., Brotman, M.A., Roy, A., Perlman, S. (2023). Defining positive emotion dysregulation: Integrating temperamental and clinical perspectives. Journal of the American Academy of Child and Adolescent Psychiatry https://scholar.google.com/citations?view_op=view_citation&hl=en&user=YUAeVRIAAAAJ&sortby=pubdate&citation_for_view=YUAeVRIAAAAJ:YohjEiUPhakC https://www.sciencedirect.com/science/article/pii/S0890856722012473 

Freitag, G., Grassie, H.L., Comer, J., Enrich-May, J., Brotman, M.A. (2023). Systematic Review: Questionnaire-based measurement of emotion dysregulation in children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry

Gang, C., Pine, D., Brotman, M., Smith, A., Cox, R., Taylor, P., Haller, S. (2022). Hyperbolic trade-off: The importance of balancing trial and subject sample sizes in neuroimaging . NeuroImage 247.

Ravi, S., Havewala, M., Kircanski, K., Brotman, M., Schneider, L., Degnan, K., . . . Filippi, C. (2022). Parenting and childhood irritability: Negative emotion socialization and parental control moderate the development of irritability. Development and Psychopathology, 1-10. doi:10.1017/S0954579421001346 

Tseng, W., Abend, R., Gold, A., Brotman, M., (2021). Neural correlates of extinguished threat recall underlying the commonality between pediatric anxiety and irritability . Journal of Affective Disorders 295, 920-929.

Gang, C., Pine, D., Brotman, M., Smith, A., Cox, R., Haller, S. (2021). Trial and error: A hierarchical modeling approach to test-retest reliability . NeuroImage 245.

Naim, R., Goodwin, M., Dombek, K., Revzina, O., Agorsor, C., Lee, K., Zapp, C., … Brotman, M., (2021) Cardiovascular reactivity as a measure of irritability in a transdiagnostic sample of youth: Preliminary associations. International Journal of Methods in Psychiatric Research, 30. https://doi.org/10.1002/mpr.1890 

Naim, R., Smith, A., Chue, A., Grassie, H., Linke, J., Dombek, K., . . . Kircanski, K. (2021). Using ecological momentary assessment to enhance irritability phenotyping in a transdiagnostic sample of youth. Development and Psychopathology, 33(5), 1734-1746. doi:10.1017/S0954579421000717 

Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study

SP Haller, J Stoddard, C Botz-Zapp, M Clayton, C MacGillivray, ... (2021). Computerized Interpretation Bias Training for Disruptive Mood Dysregulation Disorder: A Fast-Fail Study . Journal of the American Academy of Child & Adolescent Psychiatry

Rationale and validation of a novel mobile application probing motor inhibition: Proof of concept of CALM-IT

EM Cardinale, R Naim, SP Haller, R German, C Botz-Zapp, J Bezek, ... (2021). Rationale and validation of a novel mobile application probing motor inhibition: Proof of concept of CALM-IT . PloS one 16 (6), e0252245

Attention bias to negative versus non-negative faces is related to negative affectivity in a transdiagnostic youth sample

A Harrewijn, R Abend, R Naim, SP Haller, CM Stavish, MA Bajaj, ... (2021). Attention bias to negative versus non-negative faces is related to negative affectivity in a transdiagnostic youth sample . Journal of Psychiatric Research 138, 514-518

Across-subjects multiple baseline trial of exposure-based cognitive-behavioral therapy for severe irritability: a study protocol

R Naim, K Kircanski, A Gold, RE German, M Davis, S Perlstein, M Clayton, ... (2021). Across-subjects multiple baseline trial of exposure-based cognitive-behavioral therapy for severe irritability: a study protocol . BMJ open 11 (3), e039169

Computational modeling of attentional impairments in Disruptive Mood Dysregulation and Attention Deficit/hyperactivity Disorder

Haller, S.P., Stoddard, J., Pagliaccio, D., Bui, H., MacGillivray, C., Brotman, M.A. (in press). Computational modeling of attentional impairments in Disruptive Mood Dysregulation and Attention Deficit/hyperactivity Disorder . Journal of the American Academy of Child and Adolescent Psychiatry.

Self-efficacy as a target for neuroscience research on moderators of treatment outcomes in pediatric anxiety

Lewis, K.M., Matsumoto, C., Cardinale, E., Jones, E.L., Gold, A.L, Stringaris, A., Leibenluft, E., Pine, D.S., Brotman, M.A. (2020). Self-efficacy as a target for neuroscience research on moderators of treatment outcomes in pediatric anxiety. Journal of Child and Adolescent Psychopharmacology, 30, 205-214. DOI: https://doi.org/10.1089/cap.2019.0130 

Exposure-based CBT for disruptive mood dysregulation disorder: An evidence-based case study

Linke, J.O., Kircanski, K., Brooks, J., Perhamus, G., Gold, A.L., Brotman, M.A. (2020). Exposure-based CBT for disruptive mood dysregulation disorder: An evidence-based case study . Behavior Therapy, 51, 207-364. DOI: 10.1016/j.beth.2019.05.007 

White matter microstructure in pediatric bipolar disorder and disruptive mood dysregulation

Linke, J., Stavish, C., Adleman, N., Sarlls, J., Leibenluft, E., Brotman, M.A. (2020). White matter microstructure in pediatric bipolar disorder and disruptive mood dysregulation . Journal of the American Academy of Child and Adolescent Psychiatry, 59, 1135-1145. DOI: 10.1016/j.jaac.2019.05.035 

The Clinician Affective Reactivity Index: Validity and reliability of a clinician-rated assessment of irritability

Haller, S.P., Kircanski, K., Stringaris, A., Clayton, M., Bui, H., Agorsor, C., Cardenas, S.I., Towbin, K.E., Pine, D.S., Leibenluft, E., Brotman, M.A. (2020). The Clinician Affective Reactivity Index: Validity and reliability of a clinician-rated assessment of irritability . Behavior Therapy, 51, 283-293. DOI: 10.1016/j.beth.2019.10.005 

White matter microstructure in youth with and at risk for bipolar disorder

Linke, J.O., Stavish, C., Adleman, N.E., Sarlls, J., Towbin, K.E., Pine, D.S., Leibenluft, E., Brotman, M.A. (2020). White matter microstructure in youth with and at risk for bipolar disorder . Bipolar Disorders, 22, 163-173. DOI: https://doi.org/10.1111/bdi.12885 

Efficacy and mechanisms underlying a gamified attention-bias modification training in anxious youth: Protocol for a randomized controlled trial

Linke, J.O., Pagliaccio, D., Lewis, K., Silverman, W., Bar-Haim, Y., Pine, D.S., Brotman, M.A. (2019). Efficacy and mechanisms underlying a gamified attention-bias modification training in anxious youth: Protocol for a randomized controlled trial . BMC Psychiatry, 19, 246. DOI: https://doi.org/10.1186/s12888-019-2224-2 

Exposure therapy for pediatric irritability: Theory and potential mechanisms

Kircanski, K., Craske, M.G., Averbeck, B.B., Pine, D.S., Leibenluft, E., Brotman, M.A. (2019). Exposure therapy for pediatric irritability: Theory and potential mechanisms. Behaviour Research and Therapy, 118, 141-149. DOI: 10.1016/j.brat.2019.04.007 

Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach

Cardinale, E.M., Kircanski, K., Brooks, J., Gold, A.L., Towbin, K.E., Pine, D.S., Leibenluft, E., Brotman, M.A. (2019). Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach . Development and Psychopathology, 31, 917-929. DOI: 10.1017/S095457941900035X 

A latent variable approach to differentiating neural mechanisms of irritability and anxiety in youth

Kircanski, K., White, L.K., Tseng, W.-L., Wiggins, J.L., Frank, H., Sequeira, S., Zhang, S., Abend, R., Towbin, K.E., Stringaris, A., Pine, D.S., Leibenluft, E., Brotman, M.A. (2018). A latent variable approach to differentiating neural mechanisms of irritability and anxiety in youth . Journal of the American Medical Association Psychiatry, 75, 631-639. PMID:29625429 DOI: 10.1001/jamapsychiatry.2018.0468

Psychosocial treatment of irritability in youth

Kircanski, K., Clayton, M.E., Leibenluft, E., Brotman, M.A. (2018). Psychosocial treatment of irritability in youth. (2018). Current Treatment Options in Psychiatry, 5, 129-140. DOI: 10.1007/s40501-018-0141-5 

Irritability in youths: A translational model

Brotman, M.A., Kircanski, K., Stringaris, A., Pine, D.S., Leibenluft, E. (2017). Irritability in youths: A translational model . American Journal of Psychiatry, 174, 520-532. PMID: 28103715 DOI:10.1176/appi.ajp.2016.16070839 

Irritability in children and adolescents

Brotman, M.A., Kircanski, K., Leibenluft, E. (2017). Irritability in children and adolescents . Annual Review of Clinical Psychology, 13, 317-341. PMID: 28482689 DOI:10.1146/annurev-clinpsy-032816-044941 

Identifying moderators of the adherence-outcome relation in cognitive therapy for depression

Sasso, K.E., Strunk, D.R., Braun, J.D., DeRubeis, R.J., Brotman, M.A. (2015). Identifying moderators of the adherence-outcome relation in cognitive therapy for depression . Journal of Consulting and Clinical Psychology, 83, 976-984. PMID: 26214542 DOI: 10.1037/ccp0000045

Amygdala activation during emotion processing of neutral faces in children with severe mood dysregulation versus ADHD or bipolar disorder

Brotman, M.A., Rich, B.A., Guyer, A.E., Lunsford, J.R., Horsey, S.E., Reising, M.M., Thomas, L.A., Fromm, S.J., Towbin, K., Pine, D.S., Leibenluft, E. (2010). Amygdala activation during emotion processing of neutral faces in children with severe mood dysregulation versus ADHD or bipolar disorder . American Journal of Psychiatry, 167, 61-69. PMID:19917597 PMCID: PMC3075433 DOI: 10.1176/appi.ajp.2009.09010043

Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children

Brotman, M.A., Schmajuk, M., Rich, B.A., Dickstein, D.P., Guyer, A.E., Costello, E.J., Egger, H.L., Angold, A., Pine, D.S., Leibenluft, E. (2006). Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children . Biological Psychiatry, 60, 991-997. PMID:17056393 DOI: 10.1016/j.biopsych.2006.08.042