Daniel Zaldivar Perez
+1 301 827 5082
Daniel Zaldivar received his PhD in Systems Neuroscience from the Max Planck Institute for Biological Cybernetics and the University of Tuebingen under Nikos Logothetis. His doctoral work focused at understanding the role of different neuromodulators on shaping the neuro-vascular coupling relationship. Daniel Zaldivar joined the Section on Cognitive Neurophysiology and Imaging to study the intrinsic dynamics and functional role of basal forebrain (BFB). Although certain features of the cholinergic neurons in the BFB have been studied in detail, including their coarse distribution of anatomical projections, their brain-wide functional roles remain poorly characterized, particularly in primates. This gap in knowledge can be ascribed to a lack of experimental techniques allowing for (1) mapping of cell-type specific anatomical projections, and (2) systematically specifying the intrinsic dynamics and spatial distribution of these projections across distributed brain networks.
Zaldivar D, Rauch A, Logothetis NK, Goense J. Two distinct profiles of fMRI and neurophysiological activity elicited by acetylcholine in visual cortex. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E12073-E12082. PMID: 30510000.
Zaldivar D, Goense J, Lowe SC, Logothetis NK, Panzeri S. Dopamine Is Signaled by Mid-frequency Oscillations and Boosts Output Layers Visual Information in Visual Cortex. Curr Biol. 2018 Jan 22;28(2):224-235.e5. PMID: 2018/01/09 06:00.
Fichtner ND, Giapitzakis IA, Avdievich N, Mekle R, Zaldivar D, Henning A, Kreis R. In vivo characterization of the downfield part of 1 H MR spectra of human brain at 9.4 T: Magnetization exchange with water and relation to conventionally determined metabolite content. Magn Reson Med. 2018 Jun;79(6):2863-2873. PMID: 29034505.
Zaldivar D, Rauch A, Whittingstall K, Logothetis NK, Goense J. Dopamine-induced dissociation of BOLD and neural activity in macaque visual cortex. Curr Biol. 2014 Dec 1;24(23):2805-11. PMID: 25456449.
von Pföstl V, Li J, Zaldivar D, Goense J, Zhang X, Serr N, Logothetis NK, Rauch A. Effects of lactate on the early visual cortex of non-human primates, investigated by pharmaco-MRI and neurochemical analysis. Neuroimage. 2012 May 15;61(1):98-105. PMID: 22426350.
Li J, von Pföstl V, Zaldivar D, Zhang X, Logothetis N, Rauch A. Measuring multiple neurochemicals and related metabolites in blood and brain of the rhesus monkey by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass spectrometry. Anal Bioanal Chem. 2012 Mar;402(8):2545-54. PMID: 21956265.
Zaldivar D, García MC, Sánchez JA. Ciliary neurotrophic factor promotes inactivation of muscle Ca2+ channels via PKC. Biochem Biophys Res Commun. 2005 Dec 23;338(3):1572-7. PMID: 16274672.