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Transforming the understanding
and treatment of mental illnesses.

NIMH’s Role in the NIH HEAL Initiative

National Institutes of Health (NIH) HEAL (Helping to End Addiction Long-term) Initiative


The National Institute of Mental Health (NIMH) is playing a major role in the National Institutes of Health (NIH) Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, an aggressive, trans-NIH effort to speed scientific solutions to stem the national opioid public health crisis. Launched in April 2018, the initiative is focused on improving prevention and treatment strategies for opioid misuse and addiction, and enhancing pain management.

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NIMH, in partnership with other NIH Institutes, has invited research to adapt the collaborative care model – a specific service delivery model for treating mental and behavioral health conditions in primary care settings – to meet the needs of individuals with opioid use disorder (OUD) and co-occurring mental health conditions. Large clinical trials conducted in community practice settings under real-world demands may be useful to develop, optimize, and test collaborative models. These trials could offer Medication-Assisted Treatment (MAT) for OUD alongside appropriate and evidence-based treatment for mental health conditions frequently encountered in primary care, such as mood and anxiety disorders.

NIMH-Supported NIH HEAL Initiative Projects

NIMH is coordinating the following research project around the country:
Optimizing Collaborative Care Model for Individuals with Opioid Use Disorders and Mental Health Conditions

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For additional information on NIMH’s role in the NIH HEAL Initiative, please contact Megan Kinnane at For general inquiries about the NIH HEAL Initiative, please contact

Additional Resources

Last Revised: July 2019